Market Cap 1.09B
Revenue (ttm) 203.07M
Net Income (ttm) -54.84M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 28.13
Profit Margin -27.01%
Debt to Equity Ratio -255.20
Volume 1,065,500
Avg Vol 1,940,970
Day's Range N/A - N/A
Shares Out 165.92M
Stochastic %K 42%
Beta 0.52
Analysts Strong Sell
Price Target $11.14

Company Profile

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. The company offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the...

Industry: Biotechnology
Sector: Healthcare
Phone: 844 445 5704
Address:
1375 West Fulton Street, Suite 1300, Chicago, United States
DixonCider
DixonCider Feb. 24 at 10:56 PM
$XERS listen to the $CORT ER phone call. They are projecting $900M in revenue and strong Cushing demands in 2026. This can only mean big things for Recorlev as well. Korlym 2.0 meeting with the FDA is not happening until April sometime in which I think they have to do additional studies or something. Minimum puts that out a full year. Cort had manufacturing tablet issues November-January/February after switching suppliers which is common in any manufacturing business trying to ramp up and get a flow in my professional experience. They still seem to be very disappointed/disconnected from what that CRL said to what they think. If the ovarian study has the same kind of disconnect and confusion has Korlym 2.0 then could be trouble…. For Xeris very promising to hear $900M in Cushing strong demand which means John better give some damn good guidance.
0 · Reply
therealpoub
therealpoub Feb. 24 at 10:37 PM
$XERS So they announced 2025 revenue to be $292M Through 3 quarters they were at $206M So that leaves us with $86M for Q4. This will be an interesting set of numbers since my math is not mathing (my estimate on product is below). Where do they come up with another $5-6M? Either they crushed it with Recorlev or someone is paying us for something else.... Thoughts as we head into earnings next week.
1 · Reply
murahrah
murahrah Feb. 24 at 9:12 PM
$XERS If these guys preannounced only to lay an egg on the Forecast, then they deserve what they get. Hard to imagine they would be that foolish, but you never know.
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 24 at 7:18 PM
$XERS Current Stock Price: $6.68 Contracts to trade: $7.5 XERS Mar 20 2026 Call Entry: $0.25 Exit: $0.32 ROI: 29% Hold ~20 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
LiddyBuck
LiddyBuck Feb. 24 at 5:37 PM
$XERS Guys - we need to talk. My OG's remember when Paul was talking about buying another company should an opportunity present itself and it didn't go over well. So as far as I know no one ever figured out why he left. Seemed as though he was ousted but we don't 100% know. Ok, he joins the board at Vistagen and has already left. That was quick so what on earth was that about? There was someone on their board saying that Xeris is gonna buy Vistagen and I went "oh $%@*" because you know that would tank our stock. Could that be what's going on? All this CORT news and we can't even hold the $7's. I'm not that familiar with Vistagen so maybe someone like Dave can chime in but does anyone know if their nasal spray would make any sense being used with our tech? Doesn't make sense to me. I initially thought he joined their board to redeem his self esteem or something but I'm nervous it did have something to do with Xeris. We need discussion like the old days so let's hear it.
5 · Reply
ppl_first
ppl_first Feb. 24 at 4:57 PM
$XERS Drag: Commercial endocrinology with modest growth and payer friction. Recovery: Script growth acceleration required. Otherwise capped upside.
1 · Reply
Alon_R
Alon_R Feb. 24 at 3:30 PM
$XERS Take note-> a groundbreaking guidance from Xeris regarding ~$400M in revenues (~85% gross margins) would signal a better, or far better, year than the superb 2025 for Xeris (a year in which it tripled its valuation while reaching a peak of $10). Such performance could easily translate into a potential peak of ~$20-30 in 2026. It would also indicate phenomenal QoQ potential growth for Xeris. It would mean that Recorlev has become the central standard of care in hypercortisolism/Cushing's syndrome. Add to that XP-8121 entering Phase 3, and I believe market forces will understand at that point that Xeris is heading toward billions of dollars in revenue with very high margins, and the valuation will adjust accordingly. I personally expect around ~$400M in revenue. However, knowing Xeris management, they tend to guide conservatively and then exceed their initial guidance. So if they declare anything at or above $370M level, it would be a very strong statement, to say the least.
0 · Reply
simonig1
simonig1 Feb. 24 at 3:14 PM
$XERS I think XERS has a GREAT Management team that has Delivered. But then some people have a short attention span and are never satisfied. Check the chart below. The stock has trippled in the last 1.5 years at the current price. Note that the management's job is to grow the Business NOT to keep tabs on the daily stock price. When mangement takes care of and grows the business, the stock price will take care of itself. We have GREAT Management!!!
1 · Reply
Nizmeister
Nizmeister Feb. 24 at 2:01 PM
$XERS Earnings less than 1 week away. I’m expecting the following: -rev beat (already announced) -EPS of atleast 0.04 (need roughly 6.6 million in profit. We brought in 600k profit q3 off 74.4 million and did almost 12 million more in revenue q4 so just need half of that increase to be profit) -xp-8121 phase 3 on track to start this year -Rev guidance up to atleast 400 million for the year.
0 · Reply
DixonCider
DixonCider Feb. 24 at 1:20 PM
$XERS Mangement needs to take the fuckin ball & run with this Q4+ 2026 guidance of $400M. They need to address and layout the Levo study and some better TL. It’s only been two full years and we still haven’t got confirmation on anything. Enrollment, First In/last dose TL, etc. They wont address the failure in Europe but they should and if anything is coming from there or will in the future.. Allison is still a lazy no good overpaid pos. Paul had a good choice picking Recorlev w. his back against the wall and no other options. Maybe overpaid when diluting us by nearly 100%, and then diluting us more and the CVR, but we didn’t go bankrupt. 🤷‍♂️ They need to say Korlym 2.0 patients that were planning to switch will come to us and we will be growing even faster. Also Gvoke sales memb should probably be fired for the lack of growth against nose pepper spray Recorlev: $50M/$60M/$71/$82M -$263M Kevysis- $11M/$11.5M/$12M/$12.5M -$47M Gvoke- $23.5M/$25M/$26M/$27.5M- $102M Total- $412M
0 · Reply
Latest News on XERS
Xeris In Recorlev-Fuelled Growth: Why I Choose To Buy

Sep 5, 2025, 10:03 AM EDT - 6 months ago

Xeris In Recorlev-Fuelled Growth: Why I Choose To Buy


Xeris Announces Details for Analyst & Investor Day

May 20, 2025, 7:30 AM EDT - 10 months ago

Xeris Announces Details for Analyst & Investor Day


Xeris Biopharma Holdings: Looking For More Growth In Q1 Earnings

May 7, 2025, 11:51 AM EDT - 10 months ago

Xeris Biopharma Holdings: Looking For More Growth In Q1 Earnings


Xeris Announces Changes to Its Board of Directors

Mar 28, 2025, 8:00 AM EDT - 11 months ago

Xeris Announces Changes to Its Board of Directors


Xeris Appoints Anh Nguyen, MD, MBA as Chief Medical Officer

Feb 24, 2025, 8:00 AM EST - 1 year ago

Xeris Appoints Anh Nguyen, MD, MBA as Chief Medical Officer


Xeris to Participate in Upcoming Investor Conferences

Feb 5, 2025, 8:00 AM EST - 1 year ago

Xeris to Participate in Upcoming Investor Conferences


Xeris Expects to Exceed Full-Year 2024 Financial Guidance

Jan 10, 2025, 7:00 AM EST - 1 year ago

Xeris Expects to Exceed Full-Year 2024 Financial Guidance


Xeris Biopharma Reports Third Quarter 2024 Financial Results

Nov 8, 2024, 7:00 AM EST - 1 year ago

Xeris Biopharma Reports Third Quarter 2024 Financial Results


Xeris Biopharma: Time For A Reassessment

Oct 9, 2024, 11:33 AM EDT - 1 year ago

Xeris Biopharma: Time For A Reassessment


Xeris Biopharma Announces CEO Succession Plan

Jul 8, 2024, 7:00 AM EDT - 1 year ago

Xeris Biopharma Announces CEO Succession Plan


DixonCider
DixonCider Feb. 24 at 10:56 PM
$XERS listen to the $CORT ER phone call. They are projecting $900M in revenue and strong Cushing demands in 2026. This can only mean big things for Recorlev as well. Korlym 2.0 meeting with the FDA is not happening until April sometime in which I think they have to do additional studies or something. Minimum puts that out a full year. Cort had manufacturing tablet issues November-January/February after switching suppliers which is common in any manufacturing business trying to ramp up and get a flow in my professional experience. They still seem to be very disappointed/disconnected from what that CRL said to what they think. If the ovarian study has the same kind of disconnect and confusion has Korlym 2.0 then could be trouble…. For Xeris very promising to hear $900M in Cushing strong demand which means John better give some damn good guidance.
0 · Reply
therealpoub
therealpoub Feb. 24 at 10:37 PM
$XERS So they announced 2025 revenue to be $292M Through 3 quarters they were at $206M So that leaves us with $86M for Q4. This will be an interesting set of numbers since my math is not mathing (my estimate on product is below). Where do they come up with another $5-6M? Either they crushed it with Recorlev or someone is paying us for something else.... Thoughts as we head into earnings next week.
1 · Reply
murahrah
murahrah Feb. 24 at 9:12 PM
$XERS If these guys preannounced only to lay an egg on the Forecast, then they deserve what they get. Hard to imagine they would be that foolish, but you never know.
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 24 at 7:18 PM
$XERS Current Stock Price: $6.68 Contracts to trade: $7.5 XERS Mar 20 2026 Call Entry: $0.25 Exit: $0.32 ROI: 29% Hold ~20 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
LiddyBuck
LiddyBuck Feb. 24 at 5:37 PM
$XERS Guys - we need to talk. My OG's remember when Paul was talking about buying another company should an opportunity present itself and it didn't go over well. So as far as I know no one ever figured out why he left. Seemed as though he was ousted but we don't 100% know. Ok, he joins the board at Vistagen and has already left. That was quick so what on earth was that about? There was someone on their board saying that Xeris is gonna buy Vistagen and I went "oh $%@*" because you know that would tank our stock. Could that be what's going on? All this CORT news and we can't even hold the $7's. I'm not that familiar with Vistagen so maybe someone like Dave can chime in but does anyone know if their nasal spray would make any sense being used with our tech? Doesn't make sense to me. I initially thought he joined their board to redeem his self esteem or something but I'm nervous it did have something to do with Xeris. We need discussion like the old days so let's hear it.
5 · Reply
ppl_first
ppl_first Feb. 24 at 4:57 PM
$XERS Drag: Commercial endocrinology with modest growth and payer friction. Recovery: Script growth acceleration required. Otherwise capped upside.
1 · Reply
Alon_R
Alon_R Feb. 24 at 3:30 PM
$XERS Take note-> a groundbreaking guidance from Xeris regarding ~$400M in revenues (~85% gross margins) would signal a better, or far better, year than the superb 2025 for Xeris (a year in which it tripled its valuation while reaching a peak of $10). Such performance could easily translate into a potential peak of ~$20-30 in 2026. It would also indicate phenomenal QoQ potential growth for Xeris. It would mean that Recorlev has become the central standard of care in hypercortisolism/Cushing's syndrome. Add to that XP-8121 entering Phase 3, and I believe market forces will understand at that point that Xeris is heading toward billions of dollars in revenue with very high margins, and the valuation will adjust accordingly. I personally expect around ~$400M in revenue. However, knowing Xeris management, they tend to guide conservatively and then exceed their initial guidance. So if they declare anything at or above $370M level, it would be a very strong statement, to say the least.
0 · Reply
simonig1
simonig1 Feb. 24 at 3:14 PM
$XERS I think XERS has a GREAT Management team that has Delivered. But then some people have a short attention span and are never satisfied. Check the chart below. The stock has trippled in the last 1.5 years at the current price. Note that the management's job is to grow the Business NOT to keep tabs on the daily stock price. When mangement takes care of and grows the business, the stock price will take care of itself. We have GREAT Management!!!
1 · Reply
Nizmeister
Nizmeister Feb. 24 at 2:01 PM
$XERS Earnings less than 1 week away. I’m expecting the following: -rev beat (already announced) -EPS of atleast 0.04 (need roughly 6.6 million in profit. We brought in 600k profit q3 off 74.4 million and did almost 12 million more in revenue q4 so just need half of that increase to be profit) -xp-8121 phase 3 on track to start this year -Rev guidance up to atleast 400 million for the year.
0 · Reply
DixonCider
DixonCider Feb. 24 at 1:20 PM
$XERS Mangement needs to take the fuckin ball & run with this Q4+ 2026 guidance of $400M. They need to address and layout the Levo study and some better TL. It’s only been two full years and we still haven’t got confirmation on anything. Enrollment, First In/last dose TL, etc. They wont address the failure in Europe but they should and if anything is coming from there or will in the future.. Allison is still a lazy no good overpaid pos. Paul had a good choice picking Recorlev w. his back against the wall and no other options. Maybe overpaid when diluting us by nearly 100%, and then diluting us more and the CVR, but we didn’t go bankrupt. 🤷‍♂️ They need to say Korlym 2.0 patients that were planning to switch will come to us and we will be growing even faster. Also Gvoke sales memb should probably be fired for the lack of growth against nose pepper spray Recorlev: $50M/$60M/$71/$82M -$263M Kevysis- $11M/$11.5M/$12M/$12.5M -$47M Gvoke- $23.5M/$25M/$26M/$27.5M- $102M Total- $412M
0 · Reply
ForTGTX
ForTGTX Feb. 23 at 9:11 PM
$XERS I don’t think that she will go up much higher after the 4th qr earning report on 3-2, but it could dive if the CEO delivers slow revenue growth or weak revenue guidance. I wouldn’t be surprised to see $5 or even $4 on the earning date. What XERS really needs is that we need a new CEO and management team who can aggressively turn things around 🥲🥲
5 · Reply
n9zro
n9zro Feb. 23 at 8:43 PM
$XERS price action is not encouraging not gonna lie but no this is not going to 3...
1 · Reply
nIMBO_55Pip
nIMBO_55Pip Feb. 23 at 8:38 PM
$XERS biotech low attention tight range if volume expands breakout bias
0 · Reply
simonig1
simonig1 Feb. 23 at 7:47 PM
$XERS OT: Just sharing another opportunity. As I have noted previously I have three biotechs in which I am invested. They are XERS, CHRS & VNDA. VNDA received its second FDA approval within two months (on two separate drugs) after the market close on Friday. The stock was halted after hours on Friday and allowed to trade after the news was released after hours. They are an extremely undervalued stock projecting $230 to $260 million in Revenue for this year on only the three drugs they are currently marketing. The two drugs approved recently will start marketing around Q3. They have about $12 million in debt and ~$260 million in cash and a very low Market Cap. Below is their pipeline and a link to a post from "X" which goes over some details. Please do your own Due Diligence if you're interested. link to "X": https://x.com/the_analyst_24/status/2025872387133374883
1 · Reply
Nano_Nick
Nano_Nick Feb. 23 at 4:22 PM
$XERS Lickin' my chops. One more week before earnings...
0 · Reply
StarF
StarF Feb. 23 at 4:00 PM
$XERS Cort green with several bad news and xers is trading way under all the good news we had in January... Makes no sense..
2 · Reply
Alon_R
Alon_R Feb. 23 at 3:43 PM
$XERS According to my perspective, Xeris will very soon move far north of $10. This expectation is based on strong guidance, which I believe is very likely. and on the company's fulfillment of that guidance, as it did in 2025, Which i believe is very likely. Always keep in mind the data, not anyone's rhetoric (not even mine). Remember -> that it is very rare to find a growing biotech company with approximately $400M in revenue, around 85% gross margins, expanding profits, and a $2–5B Real pipeline opportunity, while its market cap is below $3–4B (with $3B implying roughly $20 per share for Xeris). That's my view - do your own due diligence.
2 · Reply
JustTradingHoy
JustTradingHoy Feb. 23 at 3:30 PM
$XERS company pre announced good numbers and the stock went to $8. Today is $6.58 Bought shares. Also buying $SOFI
1 · Reply
BarbarianTrades
BarbarianTrades Feb. 23 at 1:29 PM
$XERS looks like it’s headed to fill the gap back in August down $5.70-5.80 area
2 · Reply
Alon_R
Alon_R Feb. 23 at 11:39 AM
$XERS My Take on Xeris (pre guidance). It's all about the numbers & forward-looking. Based on current data, In my view, Xeris 2026 guidance could be the strongest in company history. at least on par with its initial 2025 guidance. Management has a track record of issuing relatively conservative guidance and then outperforming it. I wouldn't be surprised to see that pattern continue. I see a path toward ~$400M in revenue(even if the initial guidance will be $30-40M lower as in 2025), with ~85% gross margins, expanding profits QoQ, and self-sustainability. XP-8121 phase 3 begins along the second half of 2026. a specialty drug with $2–3B revenue potential and likely ~92% gross margins. Ph2 results were strong all around, and I'd estimate an 80–90% commercial probability for 2029–2030. Xeris is de-risking execution by: Working closely with the FDA(even down to device specifics - as needle size). Planning ~1,000 patients for Phase 3 to ensure robust data and commercial readiness.
1 · Reply
LoneBroker
LoneBroker Feb. 23 at 1:12 AM
$XERS $6.61 🐻 • RSI 36.90 • ATR% 5.11 • vol↑ Support & Resistance — UPDATED 2026-02-20 3 Days | Support: $6.26 – $6.26 | Resistance: $7.07 – $7.07 5 Days | Support: $6.26 – $6.26 | Resistance: $7.10 – $7.10 7 Days | Support: $6.26 – $6.26 | Resistance: $7.26 – $7.26 20 Days | Support: $6.26 – $6.26 | Resistance: $7.65 – $7.65 50 Days | Support: $6.26 – $6.26 | Resistance: $8.42 – $8.42 60 Days | Support: $6.26 – $6.26 | Resistance: $8.42 – $8.42 100 Days | Support: $6.26 – $6.26 | Resistance: $10.08 – $10.08 Momentum leans bearish with RSI at 36.90. Volatility sits at 5.11% ATR, indicating contraction. Volume shows vol↑, signaling trader attention to recent flow. ----------------------------------------------- 📌 RSI = momentum (0–100). >50 = strength, <50 = weakness 📌 ATR% = daily volatility (higher = bigger swings) 📌 Legend: 🐂 bullish • 🐻 bearish • 😐 neutral • vol↑ rising volume • vol↓ easing volume ⏳ Valid until: 1:00 PM PT
0 · Reply
Struin
Struin Feb. 21 at 5:05 PM
$XERS USA vote on another president; this one is a drama Trump raises global import duties from 10 to 15 percent
1 · Reply