Market Cap 71.22M
Revenue (ttm) 66.80M
Net Income (ttm) 8.57M
EPS (ttm) N/A
PE Ratio 11.27
Forward PE N/A
Profit Margin 12.83%
Debt to Equity Ratio 0.00
Volume 744,500
Avg Vol 1,801,342
Day's Range N/A - N/A
Shares Out 57.90M
Stochastic %K 53%
Beta 1.55
Analysts Strong Sell
Price Target $5.00

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
francismartinez
francismartinez Aug. 14 at 7:47 PM
$SPRO below cash in the bank
0 · Reply
Brandonswest
Brandonswest Aug. 14 at 5:03 AM
$SPRO lol Innovent Bio gas a $21.5 billion MC. UP 13% in the last month. Chinese wanna be? Clownish.
1 · Reply
Luckydog63
Luckydog63 Aug. 13 at 8:31 PM
$SPRO Terribly bad idea here. Burning $100,000 every single day. JV with a Chinese biotech. Insiders diverted cash success from the very patient long holders to chase a Chinese wanna be. Sickening way this occurred. Don't become the next fool to be played.
0 · Reply
Simplejackinvestor
Simplejackinvestor Aug. 13 at 7:01 PM
$SPRO just entered a position here with 500 shares… bad idea? just did it cause of the low, but with bio I guess how low can you go….
1 · Reply
Merlintrader
Merlintrader Aug. 13 at 9:34 AM
Spero Therapeutics ($SPRO) Stock Hub: Utebzi Economics, SP001 and the New Immunology Thesis https://www.merlintrader.com/spero-therapeutics-stock-hub/
0 · Reply
donnysu
donnysu Aug. 13 at 12:01 AM
$SPRO Under the terms of the NPA, Issuer sold to the NPA Purchasers, senior secured notes in an aggregate principal amount of $105,000,000 (the "Notes”), which Notes (i) were issued net of an original issue discount in the amount of $3,150,000, which, after giving effect to the RPA Purchase Price referenced below, reduces the aggregate $105,000,000 in gross proceeds of the NPA and RPA by 1.5%, (ii) accrue interest at 10% per annum, which interest, to the extent not paid in cash from available GSK Proceeds (as defined below) in accordance with the terms of the NPA, is capitalized and added to the principal amount of the Notes on a quarterly basis and (iii) mature nine years after the Closing Date.
0 · Reply
Brandonswest
Brandonswest Aug. 12 at 9:45 PM
$SPRO well nothing new in the ec. Anybody else hear anything maybe i missed?
0 · Reply
STLHD
STLHD Aug. 12 at 9:36 PM
$SPRO I didn't catch all of the call but I received this summary: Spero Therapeutics' leadership highlighted a shift to a "cash-rich" position, using $105 million from Healthcare Royalty to eliminate the need for near-term dilutive equity financing, thereby funding operations into late 2029. Furthermore, management emphasized that transferring commercial risks of Utebzi to GSK and hiring key clinical leadership for the SP001 program pivots the company toward long-term security and targeted, non-dilutive growth.
1 · Reply
Jonboy33
Jonboy33 Aug. 12 at 9:31 PM
$SPRO Very few questions in the Q and A!
1 · Reply
StocktwitsEarnings
StocktwitsEarnings Aug. 12 at 9:07 PM
$SPRO Q2 '26 Earnings Results & Recap Reported GAAP EPS of -$0.16 down -433.33% YoY
0 · Reply
Latest News on SPRO
Spero Therapeutics Earnings Call Transcript: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 4 days ago

Spero Therapeutics Earnings Call Transcript: Q2 2026


Spero Therapeutics Quarterly report: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 4 days ago

Spero Therapeutics Quarterly report: Q2 2026


Spero Therapeutics Earnings release: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 4 days ago

Spero Therapeutics Earnings release: Q2 2026


Spero Therapeutics Slides: Company presentation

Jul 13, 2026, 8:00 AM EDT - 4 weeks ago

Spero Therapeutics Slides: Company presentation


Spero Therapeutics Transcript: AGM 2026

Jun 23, 2026, 9:00 AM EDT - 7 weeks ago

Spero Therapeutics Transcript: AGM 2026


GSK, Spero Therapeutics announce FDA approval of Utebzi

2026-06-17T15:17:18.000Z - 2 months ago

GSK, Spero Therapeutics announce FDA approval of Utebzi

GSK


Spero Therapeutics Earnings release: Q1 2026

May 13, 2026, 4:00 PM EDT - 3 months ago

Spero Therapeutics Earnings release: Q1 2026


Spero Therapeutics Quarterly report: Q1 2026

May 13, 2026, 4:00 PM EDT - 3 months ago

Spero Therapeutics Quarterly report: Q1 2026


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 3 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 3 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 13, 2026, 8:00 AM EDT - 4 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Earnings release: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 5 months ago

Spero Therapeutics Earnings release: Q4 2025


Spero Therapeutics Annual report: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 5 months ago

Spero Therapeutics Annual report: Q4 2025


Spero Therapeutics Earnings release: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Earnings release: Q3 2025


Spero Therapeutics Quarterly report: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Quarterly report: Q3 2025


Spero Therapeutics Earnings Call Transcript: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q2 2025


Spero Therapeutics Quarterly report: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q2 2025


Spero Therapeutics Earnings release: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q2 2025


Spero Therapeutics Slides: Corporate Presentation

Jun 16, 2025, 7:00 AM EDT - 1 year ago

Spero Therapeutics Slides: Corporate Presentation


Spero Therapeutics Earnings release: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q1 2025


Spero Therapeutics Quarterly report: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q1 2025


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Earnings Call Transcript: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q4 2024


Spero Therapeutics Annual report: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Annual report: Q4 2024


Spero Therapeutics Earnings release: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q4 2024


Spero Therapeutics reports Q4 EPS (38c), consensus (31c)

2025-03-27T20:20:55.000Z - 1 year ago

Spero Therapeutics reports Q4 EPS (38c), consensus (31c)


Spero Therapeutics announces interim leadership changes

2025-01-10T12:31:40.000Z - 1 year ago

Spero Therapeutics announces interim leadership changes


Spero Therapeutics Earnings release: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Earnings release: Q3 2024


Spero Therapeutics Quarterly report: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Quarterly report: Q3 2024


Spero Therapeutics Earnings Call Transcript: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q2 2024


Spero Therapeutics Quarterly report: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q2 2024


Spero Therapeutics Earnings release: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q2 2024


Spero Therapeutics Quarterly report: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q1 2024


Spero Therapeutics Earnings release: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q1 2024


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Registration statement: Registration Filing

Mar 15, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Registration statement: Registration Filing


Spero Therapeutics Earnings Call Transcript: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q4 2023


Spero Therapeutics Annual report: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Annual report: Q4 2023


Spero Therapeutics Earnings release: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q4 2023


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


Spero Therapeutics Earnings Call Transcript: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q3 2023


Spero Therapeutics Quarterly report: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Quarterly report: Q3 2023


Spero Therapeutics Earnings release: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings release: Q3 2023


Spero Therapeutics Slides: Investor Presentation

Nov 1, 2023, 7:45 AM EDT - 3 years ago

Spero Therapeutics Slides: Investor Presentation


francismartinez
francismartinez Aug. 14 at 7:47 PM
$SPRO below cash in the bank
0 · Reply
Brandonswest
Brandonswest Aug. 14 at 5:03 AM
$SPRO lol Innovent Bio gas a $21.5 billion MC. UP 13% in the last month. Chinese wanna be? Clownish.
1 · Reply
Luckydog63
Luckydog63 Aug. 13 at 8:31 PM
$SPRO Terribly bad idea here. Burning $100,000 every single day. JV with a Chinese biotech. Insiders diverted cash success from the very patient long holders to chase a Chinese wanna be. Sickening way this occurred. Don't become the next fool to be played.
0 · Reply
Simplejackinvestor
Simplejackinvestor Aug. 13 at 7:01 PM
$SPRO just entered a position here with 500 shares… bad idea? just did it cause of the low, but with bio I guess how low can you go….
1 · Reply
Merlintrader
Merlintrader Aug. 13 at 9:34 AM
Spero Therapeutics ($SPRO) Stock Hub: Utebzi Economics, SP001 and the New Immunology Thesis https://www.merlintrader.com/spero-therapeutics-stock-hub/
0 · Reply
donnysu
donnysu Aug. 13 at 12:01 AM
$SPRO Under the terms of the NPA, Issuer sold to the NPA Purchasers, senior secured notes in an aggregate principal amount of $105,000,000 (the "Notes”), which Notes (i) were issued net of an original issue discount in the amount of $3,150,000, which, after giving effect to the RPA Purchase Price referenced below, reduces the aggregate $105,000,000 in gross proceeds of the NPA and RPA by 1.5%, (ii) accrue interest at 10% per annum, which interest, to the extent not paid in cash from available GSK Proceeds (as defined below) in accordance with the terms of the NPA, is capitalized and added to the principal amount of the Notes on a quarterly basis and (iii) mature nine years after the Closing Date.
0 · Reply
Brandonswest
Brandonswest Aug. 12 at 9:45 PM
$SPRO well nothing new in the ec. Anybody else hear anything maybe i missed?
0 · Reply
STLHD
STLHD Aug. 12 at 9:36 PM
$SPRO I didn't catch all of the call but I received this summary: Spero Therapeutics' leadership highlighted a shift to a "cash-rich" position, using $105 million from Healthcare Royalty to eliminate the need for near-term dilutive equity financing, thereby funding operations into late 2029. Furthermore, management emphasized that transferring commercial risks of Utebzi to GSK and hiring key clinical leadership for the SP001 program pivots the company toward long-term security and targeted, non-dilutive growth.
1 · Reply
Jonboy33
Jonboy33 Aug. 12 at 9:31 PM
$SPRO Very few questions in the Q and A!
1 · Reply
StocktwitsEarnings
StocktwitsEarnings Aug. 12 at 9:07 PM
$SPRO Q2 '26 Earnings Results & Recap Reported GAAP EPS of -$0.16 down -433.33% YoY
0 · Reply
rusty8350
rusty8350 Aug. 12 at 4:38 PM
$SPRO Sitting at ~$71M market cap with an estimated $140–160M+ cash after the $105M non-dilutive royalty financing in July. That’s a negative enterprise value of roughly -$70M to -$90M. Cash as of 3/31 was $56M. They closed the $105M deal mid-July against a slice of future GSK milestones + royalties on Utebzi. Runway now guided into H2 2029. Why the disconnect? • Microcap + thin liquidity • Market still pricing heavy risk on Utebzi commercial uptake and the early-stage SP001 pivot • Royalty rates start low (1% up to $750M) • Part of the future GSK cash flow is already spoken for by the financing Still… cash > market cap by a wide margin with an approved partnered asset and multi-year runway is not normal. Either the market is extremely skeptical or it’s inefficient. This dumb shit realistically can return to $3+ tomorrow and it wouldn’t suprise me much
1 · Reply
Longbuy1
Longbuy1 Aug. 12 at 6:25 AM
$SPRO 35% royalties with no cost for marketing, product launch, sales team. Still just a lab of 24 people who will be getting 35% of a block buster drug.
1 · Reply
Bigos
Bigos Aug. 11 at 9:03 PM
$SPRO SPRO’s July 2026 financing was significantly more expensive than a simple $105 million loan at 10% interest: HCRx provided approximately $103.4 million in net cash, while SPRO issued $105 million of senior secured notes bearing 10% interest that are repaid from future GSK milestone and royalty payments, with unpaid interest potentially added to principal. More importantly, SPRO also permanently sold HCRx 65% of the GSK milestone and royalty payments remaining after the loan is fully repaid, retaining only 35% of that future upside, in exchange for just $1.575 million specifically allocated to that residual interest. Thus, if Utebzi becomes highly successful, HCRx could receive substantial payments long after recovering its $105 million principal and 10% interest, meaning SPRO effectively gave up most of its remaining Utebzi licensing economics as an additional cost of obtaining the financing.
1 · Reply
Bigos
Bigos Aug. 10 at 3:27 PM
$SPRO Looks like this is heading toward $1.00, after the company gave away most of its license payment rights in exchange for a 10% interest loan.
2 · Reply
Longbuy1
Longbuy1 Aug. 8 at 3:14 AM
$SPRO soon
1 · Reply
rusty8350
rusty8350 Aug. 7 at 11:56 AM
$SPRO Prediction
1 · Reply
0xtechnerd
0xtechnerd Aug. 7 at 1:35 AM
0 · Reply
Jonboy33
Jonboy33 Aug. 6 at 9:00 PM
$SPRO That after-hours Trading volume can't be right can it?
2 · Reply
Tras477
Tras477 Aug. 6 at 5:12 PM
$SPRO do something cool, do something cool, do something cool
1 · Reply
MrLucky123
MrLucky123 Aug. 5 at 10:16 PM
$SPRO after screwing our shareholders again, we've decided now that stock is $1.20 we should give our employees more options. Esther the molester. Show me where the bad lady touched you. lol
1 · Reply
DDel
DDel Aug. 5 at 8:02 PM
$SPRO would really like to see hear from her, CEO, on the live audio call with an ending Q&A with some stock analysts. she's following bp's lead, lilly, and other bps, working with Innovent Biologics in china. spro shs now need to know more: Investor Relations Contact: Shai Biran, PhD Spero Therapeutics [email protected] https://en.innoventbio.com/InvestorsAndMedia/PressReleaseDetail?key=608
1 · Reply
spotthedog
spotthedog Aug. 5 at 1:22 PM
$SPRO Earnings call will be interesting. Unless they are totally inept (!), you have got to hope they know something about how this Chinese pipeline drug and that is the one to go after. Wall St tends to like immunology drugs, but the problem here is nothing seems to be happening until Q2 2027. Could be well oversold and could shoot back up to $1.80 levels, but what catalysts are available for it to go north of $2? A good roll out of the GSK drug (admittedly they don't get any royalties for a while) or some early findings from the Chinese developing the new drug? Thoughts everyone? For what its worth, I think the drop has gone too far now.
0 · Reply