Market Cap 116.49M
Revenue (ttm) 47.98M
Net Income (ttm) -68.57M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -142.91%
Debt to Equity Ratio 0.00
Volume 396,900
Avg Vol 827,046
Day's Range N/A - N/A
Shares Out 56.28M
Stochastic %K 100%
Beta 1.39
Analysts Sell
Price Target $5.00

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candi...

Industry: Biotechnology
Sector: Healthcare
Phone: (857) 242-1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
indievestments
indievestments Aug. 30 at 9:03 PM
$SPRO timeline here is tough. I have no doubt GSK will acquire IF SPRO gets the go ahead from the FDA. Milestones based on net sales + first commercial sales in USA/EU will be $375 million payments GSK can't avoid. Then it is a DCF calculation based on future royalties expected over patent life of tebi. The question is when would GSK and/or SPRO want to make a deal. There would still be a lot of risk after submitting NDA and getting a CRL like last time. So it's a 60 day hold after submitting NDA then 6 month priority review ... Probably takes it out to end of May/June 2026 if NDA submitted by end of October. If data is looking good, GSK take some risk and acquire before approval? Or wait and pay much higher price? Can easily see higher price here, the question is timing ... SPRO should have plenty of runway so won't be forced to sell before milestones and royalties start flowing.
1 · Reply
Carny
Carny Aug. 29 at 6:54 PM
$SPRO just checking back in and people still trying to sell this fantasy BO.
0 · Reply
DDel
DDel Aug. 28 at 9:28 PM
$SPRO i admit it, as a patient investor i love seeing shorts finally crushed to death and paying through the nose. pay back. patients lives first, shorts dead last. sooner or later it's coming. i can wait.
0 · Reply
DDel
DDel Aug. 28 at 9:14 PM
$SPRO that's not even counting global sales for gsk in early hosp sepsis patients. many lives will be saved. gsk deserves all the more $BILLIONS it will make. others may not agree, but i like gsk's ceo. she's on the ball.
0 · Reply
DDel
DDel Aug. 28 at 9:09 PM
$SPRO While GSK has not given a sales target for Blujepa, it has said it expects the medicine, along with two other medicines in development, to generate peak yearly sales of more than 2 billion pounds ($2.7 billion).
0 · Reply
DDel
DDel Aug. 28 at 9:06 PM
$SPRO be patient. gsk will own us all soon enough. we're next - https://uk.news.yahoo.com/uks-health-regulator-approves-type-232102581.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAAJ9E23HmwY43lQEtNhFvrZA3eMHksfWq6jITNVAVtBY1TvCucvlVyLrkazoWgBR2FkxILE1Z9R9Z8AOsrtRGNELFL6XTwdTeXNqEi4_p9TkanCi63I7DJfrxujjbwJmAsQZpCIHqMiUR01bRzz5tbOgHZBcUIooU05eQm-qsbJ7x
0 · Reply
Jabed206
Jabed206 Aug. 28 at 1:09 PM
$SPRO do we think its done consolidating now...
0 · Reply
DDel
DDel Aug. 27 at 7:30 PM
$SPRO calculating royalties is a waste of time. in time gsk will acquire the rest of spro, and gsk will easily market and sell tebi at fda appr, for very big global sales, not just cUti pill, hosp early sepsis need is huge, globally. shorts are doomed.
1 · Reply
Scipio88
Scipio88 Aug. 27 at 5:43 PM
$SPRO @RunningRobert1 is it too late to get in on this? How high do you expect this one to go?
1 · Reply
RunningRobert1
RunningRobert1 Aug. 27 at 5:16 PM
$SPRO It was a good morning to decide to buy today!
0 · Reply
Latest News on SPRO
Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript

Mar 27, 2025, 8:31 PM EDT - 5 months ago

Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript


Spero Therapeutics to Present at Upcoming Investor Conference

Apr 26, 2023, 8:05 AM EDT - 2 years ago

Spero Therapeutics to Present at Upcoming Investor Conference


indievestments
indievestments Aug. 30 at 9:03 PM
$SPRO timeline here is tough. I have no doubt GSK will acquire IF SPRO gets the go ahead from the FDA. Milestones based on net sales + first commercial sales in USA/EU will be $375 million payments GSK can't avoid. Then it is a DCF calculation based on future royalties expected over patent life of tebi. The question is when would GSK and/or SPRO want to make a deal. There would still be a lot of risk after submitting NDA and getting a CRL like last time. So it's a 60 day hold after submitting NDA then 6 month priority review ... Probably takes it out to end of May/June 2026 if NDA submitted by end of October. If data is looking good, GSK take some risk and acquire before approval? Or wait and pay much higher price? Can easily see higher price here, the question is timing ... SPRO should have plenty of runway so won't be forced to sell before milestones and royalties start flowing.
1 · Reply
Carny
Carny Aug. 29 at 6:54 PM
$SPRO just checking back in and people still trying to sell this fantasy BO.
0 · Reply
DDel
DDel Aug. 28 at 9:28 PM
$SPRO i admit it, as a patient investor i love seeing shorts finally crushed to death and paying through the nose. pay back. patients lives first, shorts dead last. sooner or later it's coming. i can wait.
0 · Reply
DDel
DDel Aug. 28 at 9:14 PM
$SPRO that's not even counting global sales for gsk in early hosp sepsis patients. many lives will be saved. gsk deserves all the more $BILLIONS it will make. others may not agree, but i like gsk's ceo. she's on the ball.
0 · Reply
DDel
DDel Aug. 28 at 9:09 PM
$SPRO While GSK has not given a sales target for Blujepa, it has said it expects the medicine, along with two other medicines in development, to generate peak yearly sales of more than 2 billion pounds ($2.7 billion).
0 · Reply
DDel
DDel Aug. 28 at 9:06 PM
$SPRO be patient. gsk will own us all soon enough. we're next - https://uk.news.yahoo.com/uks-health-regulator-approves-type-232102581.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAAJ9E23HmwY43lQEtNhFvrZA3eMHksfWq6jITNVAVtBY1TvCucvlVyLrkazoWgBR2FkxILE1Z9R9Z8AOsrtRGNELFL6XTwdTeXNqEi4_p9TkanCi63I7DJfrxujjbwJmAsQZpCIHqMiUR01bRzz5tbOgHZBcUIooU05eQm-qsbJ7x
0 · Reply
Jabed206
Jabed206 Aug. 28 at 1:09 PM
$SPRO do we think its done consolidating now...
0 · Reply
DDel
DDel Aug. 27 at 7:30 PM
$SPRO calculating royalties is a waste of time. in time gsk will acquire the rest of spro, and gsk will easily market and sell tebi at fda appr, for very big global sales, not just cUti pill, hosp early sepsis need is huge, globally. shorts are doomed.
1 · Reply
Scipio88
Scipio88 Aug. 27 at 5:43 PM
$SPRO @RunningRobert1 is it too late to get in on this? How high do you expect this one to go?
1 · Reply
RunningRobert1
RunningRobert1 Aug. 27 at 5:16 PM
$SPRO It was a good morning to decide to buy today!
0 · Reply
mdboss
mdboss Aug. 27 at 3:19 PM
$SPRO Stick a hypothetical run rate of annual sales of 3-5 billion for Tebi in your analysis and see what comes out the other end for a SPRO BO. Much bigger than anybody here can ever imagine! 2 billion would be chump change for GSK yet a life changer for many of us.
0 · Reply
RunningRobert1
RunningRobert1 Aug. 27 at 3:15 PM
$SPRO Question, if the company sell 749M I know they get 1% but if the company sells 751M does it get 1% on the first 750M or higher % for the whole amount?
1 · Reply
mdboss
mdboss Aug. 27 at 1:03 PM
$SPRO Tebi will garner a very high premium and the healthcare industry is thirsting for access to this drug. GSK will capitalize on this demand and the buyout price will shock everyone. I also find the complete disregard here for the value of inhaled SPR720 to be appalling.
1 · Reply
indievestments
indievestments Aug. 26 at 4:29 PM
$SPRO so the value here is the $150 million for first commercial sales in US & EU, then $225 million for sales milestones and royalties of 1% up to $750M revs, 7-9% between $750 and $1B revs and 10-12% for over $1B revs. So the question is how fast and how big can sales become for tebi over the life of the patent. GSK license agreement excludes Asia which I assume is quite a large market given the population. $1.5 billion/yr in sales would be $7.5 million on first $750 million, about $20 million for next $250 million and $50 million on next $500 million, for $80 million/yr in royalties excluding sales in Asia. Let's call it 100 million for 15 years, $1.5 billion, plus the $375 million in milestones and whatever an Asia license agreement would be worth. Call it $2.5 billion over life of patent/agreement re royalties to SPRO.. discounted back to today would be maybe $600-$800 million? Maybe $10 BO offer here. Just back of envelope math.
2 · Reply
Inc82
Inc82 Aug. 25 at 9:22 PM
$SPRO This is a dead giant.
0 · Reply
mdboss
mdboss Aug. 25 at 4:56 PM
$SPRO SPRO is a sleeping giant.
1 · Reply
Jabed206
Jabed206 Aug. 25 at 11:06 AM
0 · Reply
Wayne2022
Wayne2022 Aug. 25 at 9:49 AM
$SPRO how long for the sales to reach $750M? it’s not a good contract in hindsight, still current mc makes no sense.
1 · Reply
Jabed206
Jabed206 Aug. 22 at 11:26 PM
$SPRO check in and check out lol
0 · Reply
Ashabibi
Ashabibi Aug. 22 at 10:14 AM
$SPRO will get 25 milion upon NDA submission and another 50 million on first commercial sale. Another 25 million if its approved in Europe and sells in 2 different countries and another 25 million on 2nd anniversary of 1st US commercial sale. 1% royalties for sales up to 750 million. In other words SPRO will get 7.5 million if Tebipenem generates 750 million revenue. Don't get your hopes up, SPRO is getting peanuts dor this.
3 · Reply
GTDaytona
GTDaytona Aug. 21 at 10:37 PM
$SPRO Up another 4% after hours. Volume jumped over 500K. Something's brewing...
0 · Reply
Olg59
Olg59 Aug. 21 at 7:03 PM
$SPRO Turned myself into a daytrader of SPRO...Looks like gap is to be filled unles a buy out.
0 · Reply