Market Cap 68.90M
Revenue (ttm) 66.80M
Net Income (ttm) 8.57M
EPS (ttm) N/A
PE Ratio 4.83
Forward PE N/A
Profit Margin 12.83%
Debt to Equity Ratio 0.00
Volume 1,346,600
Avg Vol 1,819,520
Day's Range N/A - N/A
Shares Out 57.90M
Stochastic %K 16%
Beta 1.49
Analysts Strong Sell
Price Target $5.00

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
Jonboy33
Jonboy33 Jul. 26 at 8:47 PM
$SPRO Thoughts on the week ahead folks? A continuation of the high volume from Friday?
1 · Reply
Longbuy1
Longbuy1 Jul. 25 at 11:14 AM
$SPRO once royalties start rolling in in a year they'll be cash flow positive.
0 · Reply
Jonboy33
Jonboy33 Jul. 25 at 6:31 AM
$SPRO Interesting volume and price movements here yesterday. Feel like this could do anything in the next couple of weeks, move below a $1 or get back close to $2. Hopefully the latter as I am a holder! Lots of dumping yesterday but then loads of buyers to take them quickly. With the pivot to immunology and the very fast paced deal, was it a completely stupid idea (as market suggests now) or actually a shrewd one (which the market might relect on in the next week or two?) to go after a more specialised drug next and have a good cash runway which most biotech companies don't and are forever threatening dilution.
0 · Reply
RunnerSignals
RunnerSignals Jul. 24 at 8:24 PM
Comeback Kings $SPRO rebounded 12% from its low, likely short covering, while $CRCL recovered 4% and closed above its prior close on steadier buying
0 · Reply
Longbuy1
Longbuy1 Jul. 24 at 7:22 PM
$SPRO If it's 57M shares OS and they're going to have 200M in cash and no debt, price should recover.
0 · Reply
fantastex
fantastex Jul. 24 at 7:17 PM
$SPRO so much volume here. On watchlist next week. Looking for some bottom confirmation
0 · Reply
dakhnoukh
dakhnoukh Jul. 24 at 7:09 PM
$SPRO glad i sold this nonsense a while ago. took a hit after their PDUFA debacle, didn’t need to lose any more.
0 · Reply
sadie444
sadie444 Jul. 24 at 7:06 PM
$SPRO well it looks like whoever is selling is not done yet. Another million share sale order just dropped.
1 · Reply
Ma1392
Ma1392 Jul. 24 at 7:04 PM
$SPRO when will they get the 50 million milestone ?
0 · Reply
smithwaldJR
smithwaldJR Jul. 24 at 5:48 PM
$SPRO 50 mil float?
0 · Reply
Latest News on SPRO
Spero Therapeutics Slides: Company presentation

Jul 13, 2026, 8:00 AM EDT - 14 days ago

Spero Therapeutics Slides: Company presentation


Spero Therapeutics Transcript: AGM 2026

Jun 23, 2026, 9:00 AM EDT - 4 weeks ago

Spero Therapeutics Transcript: AGM 2026


GSK, Spero Therapeutics announce FDA approval of Utebzi

2026-06-17T15:17:18.000Z - 5 weeks ago

GSK, Spero Therapeutics announce FDA approval of Utebzi

GSK


Spero Therapeutics Earnings release: Q1 2026

May 13, 2026, 4:00 PM EDT - 2 months ago

Spero Therapeutics Earnings release: Q1 2026


Spero Therapeutics Quarterly report: Q1 2026

May 13, 2026, 4:00 PM EDT - 2 months ago

Spero Therapeutics Quarterly report: Q1 2026


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 3 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 3 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 13, 2026, 8:00 AM EDT - 3 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Earnings release: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 4 months ago

Spero Therapeutics Earnings release: Q4 2025


Spero Therapeutics Annual report: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 4 months ago

Spero Therapeutics Annual report: Q4 2025


Spero Therapeutics Earnings release: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Earnings release: Q3 2025


Spero Therapeutics Quarterly report: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Quarterly report: Q3 2025


Spero Therapeutics Earnings Call Transcript: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q2 2025


Spero Therapeutics Quarterly report: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q2 2025


Spero Therapeutics Earnings release: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q2 2025


Spero Therapeutics Slides: Corporate Presentation

Jun 16, 2025, 7:00 AM EDT - 1 year ago

Spero Therapeutics Slides: Corporate Presentation


Spero Therapeutics Earnings release: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q1 2025


Spero Therapeutics Quarterly report: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q1 2025


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Earnings Call Transcript: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q4 2024


Spero Therapeutics Annual report: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Annual report: Q4 2024


Spero Therapeutics Earnings release: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q4 2024


Spero Therapeutics reports Q4 EPS (38c), consensus (31c)

2025-03-27T20:20:55.000Z - 1 year ago

Spero Therapeutics reports Q4 EPS (38c), consensus (31c)


Spero Therapeutics announces interim leadership changes

2025-01-10T12:31:40.000Z - 1 year ago

Spero Therapeutics announces interim leadership changes


Spero Therapeutics Earnings release: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Earnings release: Q3 2024


Spero Therapeutics Quarterly report: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Quarterly report: Q3 2024


Spero Therapeutics Earnings Call Transcript: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q2 2024


Spero Therapeutics Quarterly report: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q2 2024


Spero Therapeutics Earnings release: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q2 2024


Spero Therapeutics Quarterly report: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q1 2024


Spero Therapeutics Earnings release: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q1 2024


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Registration statement: Registration Filing

Mar 15, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Registration statement: Registration Filing


Spero Therapeutics Earnings Call Transcript: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q4 2023


Spero Therapeutics Annual report: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Annual report: Q4 2023


Spero Therapeutics Earnings release: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q4 2023


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


Spero Therapeutics Earnings Call Transcript: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q3 2023


Spero Therapeutics Quarterly report: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Quarterly report: Q3 2023


Spero Therapeutics Earnings release: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings release: Q3 2023


Spero Therapeutics Slides: Investor Presentation

Nov 1, 2023, 7:45 AM EDT - 2 years ago

Spero Therapeutics Slides: Investor Presentation


Spero Therapeutics Proxy statement: Proxy Filing

Sep 1, 2023, 8:00 AM EDT - 3 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Aug 22, 2023, 8:00 AM EDT - 3 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Earnings Call Transcript: Q2 2023

Aug 10, 2023, 4:30 PM EDT - 3 years ago

Spero Therapeutics Earnings Call Transcript: Q2 2023


Spero Therapeutics Quarterly report: Q2 2023

Aug 10, 2023, 4:30 PM EDT - 3 years ago

Spero Therapeutics Quarterly report: Q2 2023


Spero Therapeutics Earnings release: Q2 2023

Aug 10, 2023, 4:30 PM EDT - 3 years ago

Spero Therapeutics Earnings release: Q2 2023


Jonboy33
Jonboy33 Jul. 26 at 8:47 PM
$SPRO Thoughts on the week ahead folks? A continuation of the high volume from Friday?
1 · Reply
Longbuy1
Longbuy1 Jul. 25 at 11:14 AM
$SPRO once royalties start rolling in in a year they'll be cash flow positive.
0 · Reply
Jonboy33
Jonboy33 Jul. 25 at 6:31 AM
$SPRO Interesting volume and price movements here yesterday. Feel like this could do anything in the next couple of weeks, move below a $1 or get back close to $2. Hopefully the latter as I am a holder! Lots of dumping yesterday but then loads of buyers to take them quickly. With the pivot to immunology and the very fast paced deal, was it a completely stupid idea (as market suggests now) or actually a shrewd one (which the market might relect on in the next week or two?) to go after a more specialised drug next and have a good cash runway which most biotech companies don't and are forever threatening dilution.
0 · Reply
RunnerSignals
RunnerSignals Jul. 24 at 8:24 PM
Comeback Kings $SPRO rebounded 12% from its low, likely short covering, while $CRCL recovered 4% and closed above its prior close on steadier buying
0 · Reply
Longbuy1
Longbuy1 Jul. 24 at 7:22 PM
$SPRO If it's 57M shares OS and they're going to have 200M in cash and no debt, price should recover.
0 · Reply
fantastex
fantastex Jul. 24 at 7:17 PM
$SPRO so much volume here. On watchlist next week. Looking for some bottom confirmation
0 · Reply
dakhnoukh
dakhnoukh Jul. 24 at 7:09 PM
$SPRO glad i sold this nonsense a while ago. took a hit after their PDUFA debacle, didn’t need to lose any more.
0 · Reply
sadie444
sadie444 Jul. 24 at 7:06 PM
$SPRO well it looks like whoever is selling is not done yet. Another million share sale order just dropped.
1 · Reply
Ma1392
Ma1392 Jul. 24 at 7:04 PM
$SPRO when will they get the 50 million milestone ?
0 · Reply
smithwaldJR
smithwaldJR Jul. 24 at 5:48 PM
$SPRO 50 mil float?
0 · Reply
Jonboy33
Jonboy33 Jul. 24 at 5:24 PM
$TE I'm in this and $SPRO - both been terrible this week. Thankfully the latter has shown signs of waking up in the last hour. Red on both though.
0 · Reply
sadie444
sadie444 Jul. 24 at 5:24 PM
$SPRO well as I said yesterday—once the institution that is selling (or whale) is done we will see the price rise— which is exactly what appears to be happening today. Let’s see if it continues until next week with a recovery in which case we will know that either it was the ATM being accessed, an institution selling, or a whale and now that they’re done the price should strongly
0 · Reply
Ma1392
Ma1392 Jul. 24 at 5:00 PM
$SPRO why would a pharma on pahse 2 with same asset be worth 3 billion? their candidate is much better and there will be 0 dilution. 140 million cash and if the gsk antibody perform well we still get 40% of the roilaitys. i think both phase 2 and 3 are aell funded and this should at least be 400 million market cap. Someone did not like the deal sold off. Now time for smart money to get in
0 · Reply
Jonboy33
Jonboy33 Jul. 24 at 4:56 PM
$SPRO Over 6 million volume today!
0 · Reply
Jonboy33
Jonboy33 Jul. 24 at 4:55 PM
$SPRO Woken up and very heavy volume today...
0 · Reply
Ma1392
Ma1392 Jul. 24 at 4:55 PM
$SPRO did gak buyout leaked?
1 · Reply
Jonboy33
Jonboy33 Jul. 24 at 4:51 PM
$SPRO Has it finally woken up?
0 · Reply
GeneralGainz
GeneralGainz Jul. 24 at 3:58 PM
$SPRO Seeing large almost million share orders being bought at these levels. Someone is accumulating…but why? Still holding my shares. Any ideas?
2 · Reply
Leogolas
Leogolas Jul. 24 at 3:57 PM
$SPRO offering?
1 · Reply
MikeyMcDermott
MikeyMcDermott Jul. 24 at 3:50 PM
$SPRO 766k sitting on the ask lol
0 · Reply
MikeyMcDermott
MikeyMcDermott Jul. 24 at 2:53 PM
$SPRO equity value is zero. Someone should investigate if there was self-dealing with that "non-dilutive financing" at 10% interest and surrender of 65% of tebi rights. Basically a death spiral toxic financing and the lender probably expects to take over the entire tebi royalty stream and the in-licensed drug when SPRO defaults.
0 · Reply
investedgate
investedgate Jul. 24 at 2:33 PM
$SPRO criminally bad management with that deal, turned a company with great prospects into a really bad one burning future income into oblivion. Anyone pursuing legal action?
0 · Reply