Market Cap 123.38M
Revenue (ttm) 47.98M
Net Income (ttm) -68.57M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -142.91%
Debt to Equity Ratio 0.00
Volume 440,500
Avg Vol 270,284
Day's Range N/A - N/A
Shares Out 56.34M
Stochastic %K 11%
Beta 1.46
Analysts Sell
Price Target $4.50

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candi...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
n44
n44 Feb. 3 at 7:15 PM
$SPRO The market has collapsed Today and Spero is just following the market trend at the moment.
0 · Reply
Inc82
Inc82 Feb. 3 at 6:00 PM
$SPRO Where are all the pumpers?
1 · Reply
n44
n44 Feb. 3 at 5:58 PM
$SPRO I think what also is happening, retail investors just get bored, scared and lose confidence too easily, human nature, that’s why we are called dumb retail.
0 · Reply
Inc82
Inc82 Feb. 3 at 5:52 PM
$SPRO I knew this was going back down to $1.80.
1 · Reply
n44
n44 Feb. 3 at 4:55 PM
$SPRO This should start getting better as the NDA acceptance is announced, I am disappointed that this is going down, just holding for the long term. The process is hard to swallow every day but the end result is the most important.
2 · Reply
DoctorBombay25
DoctorBombay25 Feb. 2 at 8:14 PM
$SPRO patience
0 · Reply
Bigos
Bigos Feb. 2 at 1:58 PM
$SPRO @MJ41 Who do you identify as the biggest pumper /scammer posting on here?
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 2 at 1:51 PM
$SPRO Current Stock Price: $2.20 Contracts to trade: $2.5 SPRO Feb 20 2026 Call Entry: $0.14 Exit: $0.20 ROI: 46% Hold ~20 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
n44
n44 Feb. 1 at 11:21 PM
$SPRO The Best Thing that could happen to us would be the collapse of the Ai trades, either way I would not be surprised to see some companies fail and investors will shift to other areas of the market, small Biotech companies.
0 · Reply
n44
n44 Feb. 1 at 3:25 PM
$SPRO The FDA will be posting the acceptance of the Resubmission of Tebibenem no later than the next two weeks, this will give us a boost in share price and also take some risk off. I would hope the company, (GSK and Spero) would elaborate on the Approval process and give some guidance, getting closer.
0 · Reply
Latest News on SPRO
Spero Therapeutics, Inc. (SPRO) Q2 2025 Earnings Call Transcript

Aug 12, 2025, 7:32 PM EDT - 6 months ago

Spero Therapeutics, Inc. (SPRO) Q2 2025 Earnings Call Transcript


Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript

Mar 27, 2025, 8:31 PM EDT - 11 months ago

Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


n44
n44 Feb. 3 at 7:15 PM
$SPRO The market has collapsed Today and Spero is just following the market trend at the moment.
0 · Reply
Inc82
Inc82 Feb. 3 at 6:00 PM
$SPRO Where are all the pumpers?
1 · Reply
n44
n44 Feb. 3 at 5:58 PM
$SPRO I think what also is happening, retail investors just get bored, scared and lose confidence too easily, human nature, that’s why we are called dumb retail.
0 · Reply
Inc82
Inc82 Feb. 3 at 5:52 PM
$SPRO I knew this was going back down to $1.80.
1 · Reply
n44
n44 Feb. 3 at 4:55 PM
$SPRO This should start getting better as the NDA acceptance is announced, I am disappointed that this is going down, just holding for the long term. The process is hard to swallow every day but the end result is the most important.
2 · Reply
DoctorBombay25
DoctorBombay25 Feb. 2 at 8:14 PM
$SPRO patience
0 · Reply
Bigos
Bigos Feb. 2 at 1:58 PM
$SPRO @MJ41 Who do you identify as the biggest pumper /scammer posting on here?
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 2 at 1:51 PM
$SPRO Current Stock Price: $2.20 Contracts to trade: $2.5 SPRO Feb 20 2026 Call Entry: $0.14 Exit: $0.20 ROI: 46% Hold ~20 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
n44
n44 Feb. 1 at 11:21 PM
$SPRO The Best Thing that could happen to us would be the collapse of the Ai trades, either way I would not be surprised to see some companies fail and investors will shift to other areas of the market, small Biotech companies.
0 · Reply
n44
n44 Feb. 1 at 3:25 PM
$SPRO The FDA will be posting the acceptance of the Resubmission of Tebibenem no later than the next two weeks, this will give us a boost in share price and also take some risk off. I would hope the company, (GSK and Spero) would elaborate on the Approval process and give some guidance, getting closer.
0 · Reply
Dbrookes
Dbrookes Jan. 31 at 8:42 AM
$SPRO Sure, tebipenem will get approved for cUTI/pyelo but given the high bioavailability, it will be used for intra-abdominal, ENT, PNA, and diabetic foot infections in due time. ESBL infections are only increasing. Hospitals are losing money and at every budget meeting, length of hospital stay is always a major topic. No brainer.
0 · Reply
n44
n44 Jan. 31 at 1:30 AM
$SPRO Ankit Mahadevia MD resigned and I say he had NO choice but to leave, he has no future since he and his cronie commited SEC fraud. I have no sympathy for people like him, greed and corrupt, just an opinion.
0 · Reply
n44
n44 Jan. 30 at 10:28 PM
$SPRO Good riddance to Dr Maharishi? He resigned and will per sue others, luckily the company is not responsible for his actions and no fines were incurred, the company filed an 8k today.
0 · Reply
n44
n44 Jan. 30 at 8:47 PM
$SPRO On a side note, GlaxoSmithKline has been in an upward trend and certainly flush with cash 💰 💰💰💰💰💰💰
0 · Reply
n44
n44 Jan. 30 at 8:37 PM
$SPRO Russell and small Bio stocks have been hit hard this week, many questions remain unanswered in the general market and algorithms are programmed to sell everything.
0 · Reply
Inc82
Inc82 Jan. 30 at 7:05 PM
$SPRO Back down to$1.80
1 · Reply
n44
n44 Jan. 30 at 6:55 PM
$SPRO I wish I had more money 💰 to add but for now it’s tied up, maybe next week, low volume and again impatient people.
0 · Reply
MJ41
MJ41 Jan. 30 at 6:55 PM
$SPRO for all the “buyout” pumpers on here trying to scam everyone: Translating that into equity value Step 1: SPRO royalty cash flow (base case) Assume: • Peak sales: $800M • Royalty to SPRO: ~10% (illustrative but realistic) • Peak royalty revenue: $80M/year • Operating margin on royalties: ~90% Step 2: Apply pharma multiple • Use 4×–6× peak royalty EBITDA • Value range: $320M–480M Add: • Net cash • Pipeline option value That gets you to roughly: ⸻ Most likely buyout valuation range $400M$700M enterprise value This is the center-mass outcome, not the extremes. ⸻ What that means per share (important) Assuming: • ~150–170M fully diluted shares (reasonable post-approval assumption) You get: $2.50 – $4.50 per share
4 · Reply
mdboss
mdboss Jan. 30 at 6:49 PM
$SPRO Duh. It’s always darkest before the dawn. I’m here for the BIG payday!
0 · Reply
Bigos
Bigos Jan. 30 at 4:50 PM
$SPRO Stock Price now at a 3 month low.
1 · Reply
n44
n44 Jan. 30 at 3:02 PM
$SPRO Market Makers are trying every possible way to get some volume of trades but just small insignificant trades going through, meaningless at this point.
1 · Reply
n44
n44 Jan. 30 at 2:58 PM
$SPRO Until we start seeing substantial volume all of the trading is just market manipulation, boring times and a test of patience, we are in a holding position till we advance to the next level.
0 · Reply