Market Cap 70.46M
Revenue (ttm) 66.80M
Net Income (ttm) 8.57M
EPS (ttm) N/A
PE Ratio 11.00
Forward PE N/A
Profit Margin 12.83%
Debt to Equity Ratio 0.00
Volume 362,900
Avg Vol 1,278,884
Day's Range N/A - N/A
Shares Out 58.24M
Stochastic %K 38%
Beta 1.49
Analysts Strong Sell
Price Target $5.00

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
MikeBob15
MikeBob15 Sep. 3 at 12:44 AM
$SPRO Spero Therapeutics to Present at H.C. Wainwright | SPRO Stock News Spero Therapeutics to Present at H.C. Wainwright | SPRO Stock News https://share.google/U7EHyDCzvL0tFv2B0
0 · Reply
Bigos
Bigos Sep. 1 at 3:46 PM
$SPRO . Agreed. In August 2026, SPRO replaced its unused $75 million ATM with a new $100 million Jefferies ATM and had already doubled its authorized common shares from 120 million to 240 million. At roughly $1.21 per share, fully using the ATM could mean about 82.6 million new shares, which would severely dilute existing shareholders, while also probably putting downward pressure on the stock price as new shares are sold into the market. .
0 · Reply
Luckydog63
Luckydog63 Sep. 1 at 2:30 PM
$SPRO what the filing means is that they are 100 percent ready to make a big flush. No clue how they think they are getting $300 million out of the shares and warrants at a $1.20 market valuation. The stock price would need to be above $2. Are they just playing games to try to get others out? A major dilution at $1.20 is corporate suicide. So it doesn't make sense. Well buffered with cash for awhile but burning appx 1,000,000 week with no data for a year...ouch. With that in mind, maybe they figure this is the high point and thus the right place to dilute...crazy. They already screwed shareholders once, I wouldn't trust them but there could be some other hidden plan. They had a year to dream up this path and it's probably got more pages to flop. Are
0 · Reply
FrostyOrbit
FrostyOrbit Aug. 30 at 9:26 PM
$SPRO Spero raised $105M through non-dilutive royalty financing, extending its projected cash runway into H2 2029...
0 · Reply
sadie444
sadie444 Aug. 28 at 10:52 PM
$SPRO  A quick update regarding the 8K filed after market close today. This document reflects what was authorized back in spring. It's not new information; it's simply finally filing the paperwork for what was already approved. To be clear, they are not announcing any plans to sell. They're just registering the shelf that was approved. That’s all. This is standard practice for businesses and doesn't mean they have any immediate plans to sell. Our assumption at the time was that they were likely ensuring enough shares were available. If they decide to pursue an acquisition or merger, it doesn't necessarily mean they will do so; that was just the discussion on this board at the time.
0 · Reply
focafoca99
focafoca99 Aug. 28 at 10:19 PM
$SPRO acquires up to $300M of financing through an Open Market Sale Agreement with Jefferies.
1 · Reply
MikeBob15
MikeBob15 Aug. 28 at 9:01 PM
$SPRO . I was in this a while back. I had a decent gain at the time. THEN IT STARTED TO GO DOWN!!! I put a stop loss on it and was glad I got out. Seems like most people perceived the acquisition as negative sentiment. That said , I don't think this stock has any business trading at these levels. They have over fifty million in cash on hand. No debt... and a very promising FDA approved drug with no equivalent ready to hit the market. I guess the hope among active shareholders is that the royalties and milestones from tebipenem will be enough in excess to to keep the ball rolling for their new pet project and to return value to Shareholders and get the market cap up to something realistic. Back in but keeping it tight.
1 · Reply
Luckydog63
Luckydog63 Aug. 26 at 5:00 PM
$SPRO GARBAGE!
0 · Reply
Luckydog63
Luckydog63 Aug. 25 at 10:37 PM
$SPRO another almost 1,000,000 cash Poof! Just 8 days ago last post. Oh yeah and the first data point is a year away. 50 million gone by then. About 6 to 8 years to drug approval a long long long poofing process. Glta
0 · Reply
MrLucky123
MrLucky123 Aug. 21 at 12:12 AM
$SPRO scumbags. You guys vote them back in next year you deserve what you get
1 · Reply
Latest News on SPRO
Spero Therapeutics files $300M mixed securities shelf

2026-08-28T21:10:14.000Z - 9 days ago

Spero Therapeutics files $300M mixed securities shelf


Spero Therapeutics Earnings Call Transcript: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 25 days ago

Spero Therapeutics Earnings Call Transcript: Q2 2026


Spero Therapeutics Quarterly report: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 25 days ago

Spero Therapeutics Quarterly report: Q2 2026


Spero Therapeutics Earnings release: Q2 2026

Aug 12, 2026, 5:00 PM EDT - 25 days ago

Spero Therapeutics Earnings release: Q2 2026


Spero Therapeutics Slides: Company presentation

Jul 13, 2026, 8:00 AM EDT - 7 weeks ago

Spero Therapeutics Slides: Company presentation


Spero Therapeutics Transcript: AGM 2026

Jun 23, 2026, 9:00 AM EDT - 2 months ago

Spero Therapeutics Transcript: AGM 2026


GSK, Spero Therapeutics announce FDA approval of Utebzi

2026-06-17T15:17:18.000Z - 2 months ago

GSK, Spero Therapeutics announce FDA approval of Utebzi

GSK


Spero Therapeutics Earnings release: Q1 2026

May 13, 2026, 4:00 PM EDT - 3 months ago

Spero Therapeutics Earnings release: Q1 2026


Spero Therapeutics Quarterly report: Q1 2026

May 13, 2026, 4:00 PM EDT - 3 months ago

Spero Therapeutics Quarterly report: Q1 2026


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 4 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 4 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Proxy statement: Proxy filing

Apr 13, 2026, 8:00 AM EDT - 4 months ago

Spero Therapeutics Proxy statement: Proxy filing


Spero Therapeutics Earnings release: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 5 months ago

Spero Therapeutics Earnings release: Q4 2025


Spero Therapeutics Annual report: Q4 2025

Mar 26, 2026, 4:00 PM EDT - 5 months ago

Spero Therapeutics Annual report: Q4 2025


Spero Therapeutics Earnings release: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Earnings release: Q3 2025


Spero Therapeutics Quarterly report: Q3 2025

Nov 13, 2025, 4:00 PM EST - 9 months ago

Spero Therapeutics Quarterly report: Q3 2025


Spero Therapeutics Earnings Call Transcript: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q2 2025


Spero Therapeutics Quarterly report: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q2 2025


Spero Therapeutics Earnings release: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q2 2025


Spero Therapeutics Slides: Corporate Presentation

Jun 16, 2025, 7:00 AM EDT - 1 year ago

Spero Therapeutics Slides: Corporate Presentation


Spero Therapeutics Earnings release: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q1 2025


Spero Therapeutics Quarterly report: Q1 2025

May 13, 2025, 4:00 PM EDT - 1 year ago

Spero Therapeutics Quarterly report: Q1 2025


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Earnings Call Transcript: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q4 2024


Spero Therapeutics Annual report: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Annual report: Q4 2024


Spero Therapeutics Earnings release: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings release: Q4 2024


Spero Therapeutics reports Q4 EPS (38c), consensus (31c)

2025-03-27T20:20:55.000Z - 1 year ago

Spero Therapeutics reports Q4 EPS (38c), consensus (31c)


Spero Therapeutics announces interim leadership changes

2025-01-10T12:31:40.000Z - 1 year ago

Spero Therapeutics announces interim leadership changes


Spero Therapeutics Earnings release: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Earnings release: Q3 2024


Spero Therapeutics Quarterly report: Q3 2024

Nov 14, 2024, 12:00 AM EST - 1 year ago

Spero Therapeutics Quarterly report: Q3 2024


Spero Therapeutics Earnings Call Transcript: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q2 2024


Spero Therapeutics Quarterly report: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q2 2024


Spero Therapeutics Earnings release: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q2 2024


Spero Therapeutics Quarterly report: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Quarterly report: Q1 2024


Spero Therapeutics Earnings release: Q1 2024

May 15, 2024, 4:00 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q1 2024


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Proxy statement: Proxy Filing


Spero Therapeutics Registration statement: Registration Filing

Mar 15, 2024, 8:00 AM EDT - 2 years ago

Spero Therapeutics Registration statement: Registration Filing


Spero Therapeutics Earnings Call Transcript: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q4 2023


Spero Therapeutics Annual report: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Annual report: Q4 2023


Spero Therapeutics Earnings release: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings release: Q4 2023


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


Spero Therapeutics Earnings Call Transcript: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q3 2023


Spero Therapeutics Quarterly report: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Quarterly report: Q3 2023


Spero Therapeutics Earnings release: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings release: Q3 2023


MikeBob15
MikeBob15 Sep. 3 at 12:44 AM
$SPRO Spero Therapeutics to Present at H.C. Wainwright | SPRO Stock News Spero Therapeutics to Present at H.C. Wainwright | SPRO Stock News https://share.google/U7EHyDCzvL0tFv2B0
0 · Reply
Bigos
Bigos Sep. 1 at 3:46 PM
$SPRO . Agreed. In August 2026, SPRO replaced its unused $75 million ATM with a new $100 million Jefferies ATM and had already doubled its authorized common shares from 120 million to 240 million. At roughly $1.21 per share, fully using the ATM could mean about 82.6 million new shares, which would severely dilute existing shareholders, while also probably putting downward pressure on the stock price as new shares are sold into the market. .
0 · Reply
Luckydog63
Luckydog63 Sep. 1 at 2:30 PM
$SPRO what the filing means is that they are 100 percent ready to make a big flush. No clue how they think they are getting $300 million out of the shares and warrants at a $1.20 market valuation. The stock price would need to be above $2. Are they just playing games to try to get others out? A major dilution at $1.20 is corporate suicide. So it doesn't make sense. Well buffered with cash for awhile but burning appx 1,000,000 week with no data for a year...ouch. With that in mind, maybe they figure this is the high point and thus the right place to dilute...crazy. They already screwed shareholders once, I wouldn't trust them but there could be some other hidden plan. They had a year to dream up this path and it's probably got more pages to flop. Are
0 · Reply
FrostyOrbit
FrostyOrbit Aug. 30 at 9:26 PM
$SPRO Spero raised $105M through non-dilutive royalty financing, extending its projected cash runway into H2 2029...
0 · Reply
sadie444
sadie444 Aug. 28 at 10:52 PM
$SPRO  A quick update regarding the 8K filed after market close today. This document reflects what was authorized back in spring. It's not new information; it's simply finally filing the paperwork for what was already approved. To be clear, they are not announcing any plans to sell. They're just registering the shelf that was approved. That’s all. This is standard practice for businesses and doesn't mean they have any immediate plans to sell. Our assumption at the time was that they were likely ensuring enough shares were available. If they decide to pursue an acquisition or merger, it doesn't necessarily mean they will do so; that was just the discussion on this board at the time.
0 · Reply
focafoca99
focafoca99 Aug. 28 at 10:19 PM
$SPRO acquires up to $300M of financing through an Open Market Sale Agreement with Jefferies.
1 · Reply
MikeBob15
MikeBob15 Aug. 28 at 9:01 PM
$SPRO . I was in this a while back. I had a decent gain at the time. THEN IT STARTED TO GO DOWN!!! I put a stop loss on it and was glad I got out. Seems like most people perceived the acquisition as negative sentiment. That said , I don't think this stock has any business trading at these levels. They have over fifty million in cash on hand. No debt... and a very promising FDA approved drug with no equivalent ready to hit the market. I guess the hope among active shareholders is that the royalties and milestones from tebipenem will be enough in excess to to keep the ball rolling for their new pet project and to return value to Shareholders and get the market cap up to something realistic. Back in but keeping it tight.
1 · Reply
Luckydog63
Luckydog63 Aug. 26 at 5:00 PM
$SPRO GARBAGE!
0 · Reply
Luckydog63
Luckydog63 Aug. 25 at 10:37 PM
$SPRO another almost 1,000,000 cash Poof! Just 8 days ago last post. Oh yeah and the first data point is a year away. 50 million gone by then. About 6 to 8 years to drug approval a long long long poofing process. Glta
0 · Reply
MrLucky123
MrLucky123 Aug. 21 at 12:12 AM
$SPRO scumbags. You guys vote them back in next year you deserve what you get
1 · Reply
GeneralGainz
GeneralGainz Aug. 19 at 1:50 PM
1 · Reply
Luckydog63
Luckydog63 Aug. 17 at 5:17 PM
$SPRO Let's Follow the Money CSuite secured 3 years big $$ salary GSK got what they wanted win Royalty Firm HUGE GIFTED WIN Innovent Big Win $$ 35 MM BOD 3 more years big win Shareholders sold down the river Down 40 to 50 percent. Classic move Spero.
1 · Reply
Luckydog63
Luckydog63 Aug. 17 at 3:06 PM
$SPRO Another $100,000 daily annuity payment to do nothing company. Everyday slip sliding away, could have done the right thing but personal greed won. Market discounting cash as it should.
0 · Reply
francismartinez
francismartinez Aug. 14 at 7:47 PM
$SPRO below cash in the bank
0 · Reply
Brandonswest
Brandonswest Aug. 14 at 5:03 AM
$SPRO lol Innovent Bio gas a $21.5 billion MC. UP 13% in the last month. Chinese wanna be? Clownish.
1 · Reply
Luckydog63
Luckydog63 Aug. 13 at 8:31 PM
$SPRO Terribly bad idea here. Burning $100,000 every single day. JV with a Chinese biotech. Insiders diverted cash success from the very patient long holders to chase a Chinese wanna be. Sickening way this occurred. Don't become the next fool to be played.
0 · Reply
Simplejackinvestor
Simplejackinvestor Aug. 13 at 7:01 PM
$SPRO just entered a position here with 500 shares… bad idea? just did it cause of the low, but with bio I guess how low can you go….
1 · Reply
Merlintrader
Merlintrader Aug. 13 at 9:34 AM
Spero Therapeutics ($SPRO) Stock Hub: Utebzi Economics, SP001 and the New Immunology Thesis https://www.merlintrader.com/spero-therapeutics-stock-hub/
0 · Reply
donnysu
donnysu Aug. 13 at 12:01 AM
$SPRO Under the terms of the NPA, Issuer sold to the NPA Purchasers, senior secured notes in an aggregate principal amount of $105,000,000 (the "Notes”), which Notes (i) were issued net of an original issue discount in the amount of $3,150,000, which, after giving effect to the RPA Purchase Price referenced below, reduces the aggregate $105,000,000 in gross proceeds of the NPA and RPA by 1.5%, (ii) accrue interest at 10% per annum, which interest, to the extent not paid in cash from available GSK Proceeds (as defined below) in accordance with the terms of the NPA, is capitalized and added to the principal amount of the Notes on a quarterly basis and (iii) mature nine years after the Closing Date.
0 · Reply
Brandonswest
Brandonswest Aug. 12 at 9:45 PM
$SPRO well nothing new in the ec. Anybody else hear anything maybe i missed?
0 · Reply
STLHD
STLHD Aug. 12 at 9:36 PM
$SPRO I didn't catch all of the call but I received this summary: Spero Therapeutics' leadership highlighted a shift to a "cash-rich" position, using $105 million from Healthcare Royalty to eliminate the need for near-term dilutive equity financing, thereby funding operations into late 2029. Furthermore, management emphasized that transferring commercial risks of Utebzi to GSK and hiring key clinical leadership for the SP001 program pivots the company toward long-term security and targeted, non-dilutive growth.
1 · Reply
Jonboy33
Jonboy33 Aug. 12 at 9:31 PM
$SPRO Very few questions in the Q and A!
1 · Reply