Market Cap 137.31M
Revenue (ttm) 47.98M
Net Income (ttm) -68.57M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -142.91%
Debt to Equity Ratio 0.00
Volume 251,100
Avg Vol 710,078
Day's Range N/A - N/A
Shares Out 56.28M
Stochastic %K 19%
Beta 1.55
Analysts Sell
Price Target $5.00

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candi...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
aletz
aletz Nov. 14 at 9:05 PM
$SPRO Modest acquisition scenario $500M~800M 270%~490% from the current valuation Tebi, once approved, will expand label as it's already proven for pediatric use for multiple indications Japan. Upper bands $1B~$1.5B range but this really depends on actual valuation by then. Almost zero worries for dilution. Safest bet in clinical stage bio sector.
0 · Reply
DDel
DDel Nov. 14 at 7:43 PM
$SPRO gsk knows what it has with tebi. as do i. gsk will get fda appr. spro ends. end of story. long and very
0 · Reply
HedgeAlerts
HedgeAlerts Nov. 14 at 7:02 PM
Hedge Alert Live - Protect Your Portfolio Contract: $SPRO $2.00 Put · NOV 21, 2025 Exp Entry Price: $0.05 - $0.15 Exit Price Target: $0.32 Profit Margin: +116% Hold Period: 1-3 days MAX ONLY USE THESE ALERTS ON RED/DOWN MARKET DAYS. Monetize Red Market Days: https://hedgealerts.com
0 · Reply
Drashkawisha
Drashkawisha Nov. 14 at 12:10 PM
$SPRO The Case: Focus on the Q3 2025 report (Nov 13). Fact 1: Beat consensus EPS estimates significantly (Actual: -$0.13 vs. Est: -$0.25). Fact 2: Management officially stated the current cash runway is extended to 2028. This removes the primary dilution overhang from the thesis.
0 · Reply
HedgeAlerts
HedgeAlerts Nov. 14 at 8:21 AM
Hedge Alert Live - Protect Your Portfolio Contract: $SPRO $2.00 Put · NOV 21, 2025 Exp Entry Price: $0.15 - $0.15 Exit Price Target: $0.32 Profit Margin: +115% Hold Period: 1-3 days MAX ONLY USE THESE ALERTS ON RED/DOWN MARKET DAYS. Monetize Red Market Days: https://hedgealerts.com
0 · Reply
Drashkawisha
Drashkawisha Nov. 14 at 4:20 AM
$SPRO The market is reading this completely wrong. "Mixed results"? Stop. This was a massive A+ report. EPS: They crushed estimates (Actual: -$0.13 vs. Est: -$0.25). They are burning way less cash. Revenue: Noise. THE REAL STORY: Management just confirmed CASH RUNWAY EXTENDED TO 2028. They just eliminated all near-term DILUTION RISK. This is a classic "de-risking" event. Fully funded to execute. Bullish
0 · Reply
RandomInvestor777
RandomInvestor777 Nov. 13 at 11:12 PM
$SPRO why would they buyout when they have almost all the rights to the drug? and the milestone payments aren't that much. They have no reason to pay 1b to this company
3 · Reply
AgainAagain
AgainAagain Nov. 13 at 10:42 PM
$SLS look at $SPRO a real buy out candidate. $SLS has scammed retail for more than 5 years out of hard earned money.
2 · Reply
AgainAagain
AgainAagain Nov. 13 at 10:40 PM
$SPRO makes sense that they cancelled the research on the other candidate drug. Save some unnecessary expenses. All indications point to a buy out of some form by GSK. Quite positive.
0 · Reply
mdboss
mdboss Nov. 13 at 9:28 PM
$SPRO Ha ha! Gotcha. No evidence of dilution or any risk of dilution. Cash runway to 2028 - that's absurd! SPR720 getting completely flushed just reinforces that it was all about King Tebi anyway! See you all for the big payday! Godspeed.
0 · Reply
Latest News on SPRO
Spero Therapeutics, Inc. (SPRO) Q2 2025 Earnings Call Transcript

Aug 12, 2025, 7:32 PM EDT - 3 months ago

Spero Therapeutics, Inc. (SPRO) Q2 2025 Earnings Call Transcript


Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript

Mar 27, 2025, 8:31 PM EDT - 8 months ago

Spero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call Transcript


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


aletz
aletz Nov. 14 at 9:05 PM
$SPRO Modest acquisition scenario $500M~800M 270%~490% from the current valuation Tebi, once approved, will expand label as it's already proven for pediatric use for multiple indications Japan. Upper bands $1B~$1.5B range but this really depends on actual valuation by then. Almost zero worries for dilution. Safest bet in clinical stage bio sector.
0 · Reply
DDel
DDel Nov. 14 at 7:43 PM
$SPRO gsk knows what it has with tebi. as do i. gsk will get fda appr. spro ends. end of story. long and very
0 · Reply
HedgeAlerts
HedgeAlerts Nov. 14 at 7:02 PM
Hedge Alert Live - Protect Your Portfolio Contract: $SPRO $2.00 Put · NOV 21, 2025 Exp Entry Price: $0.05 - $0.15 Exit Price Target: $0.32 Profit Margin: +116% Hold Period: 1-3 days MAX ONLY USE THESE ALERTS ON RED/DOWN MARKET DAYS. Monetize Red Market Days: https://hedgealerts.com
0 · Reply
Drashkawisha
Drashkawisha Nov. 14 at 12:10 PM
$SPRO The Case: Focus on the Q3 2025 report (Nov 13). Fact 1: Beat consensus EPS estimates significantly (Actual: -$0.13 vs. Est: -$0.25). Fact 2: Management officially stated the current cash runway is extended to 2028. This removes the primary dilution overhang from the thesis.
0 · Reply
HedgeAlerts
HedgeAlerts Nov. 14 at 8:21 AM
Hedge Alert Live - Protect Your Portfolio Contract: $SPRO $2.00 Put · NOV 21, 2025 Exp Entry Price: $0.15 - $0.15 Exit Price Target: $0.32 Profit Margin: +115% Hold Period: 1-3 days MAX ONLY USE THESE ALERTS ON RED/DOWN MARKET DAYS. Monetize Red Market Days: https://hedgealerts.com
0 · Reply
Drashkawisha
Drashkawisha Nov. 14 at 4:20 AM
$SPRO The market is reading this completely wrong. "Mixed results"? Stop. This was a massive A+ report. EPS: They crushed estimates (Actual: -$0.13 vs. Est: -$0.25). They are burning way less cash. Revenue: Noise. THE REAL STORY: Management just confirmed CASH RUNWAY EXTENDED TO 2028. They just eliminated all near-term DILUTION RISK. This is a classic "de-risking" event. Fully funded to execute. Bullish
0 · Reply
RandomInvestor777
RandomInvestor777 Nov. 13 at 11:12 PM
$SPRO why would they buyout when they have almost all the rights to the drug? and the milestone payments aren't that much. They have no reason to pay 1b to this company
3 · Reply
AgainAagain
AgainAagain Nov. 13 at 10:42 PM
$SLS look at $SPRO a real buy out candidate. $SLS has scammed retail for more than 5 years out of hard earned money.
2 · Reply
AgainAagain
AgainAagain Nov. 13 at 10:40 PM
$SPRO makes sense that they cancelled the research on the other candidate drug. Save some unnecessary expenses. All indications point to a buy out of some form by GSK. Quite positive.
0 · Reply
mdboss
mdboss Nov. 13 at 9:28 PM
$SPRO Ha ha! Gotcha. No evidence of dilution or any risk of dilution. Cash runway to 2028 - that's absurd! SPR720 getting completely flushed just reinforces that it was all about King Tebi anyway! See you all for the big payday! Godspeed.
0 · Reply
GTDaytona
GTDaytona Nov. 13 at 9:19 PM
$SPRO As of June 30, 2025, Spero had cash and cash equivalents of $31.2 million. As of September 30, 2025, Spero had cash and cash equivalents of $48.6 million.
0 · Reply
drc23w
drc23w Nov. 13 at 7:10 PM
$SPRO "The company does not intend to host a conference call" wierd.
1 · Reply
GTDaytona
GTDaytona Nov. 13 at 1:29 PM
$SPRO AUG 12TH WEB TRANSCRIPT
0 · Reply
DDel
DDel Nov. 12 at 8:52 PM
$SPRO hold on, going much higher with gsk, gsk will get it done. very
0 · Reply
TrkDvr
TrkDvr Nov. 12 at 3:01 PM
$SPRO Luck undeniably is a big part of trading. Probably the biggest part is patience however.
0 · Reply
mdboss
mdboss Nov. 12 at 1:04 PM
$SPRO What's the goose that lays the golden egg worth to GSK? Tebi sale projections over the next decade may provide a clue. I believe sales could easily tally $50 billion, if not more, so a $1-2 billion outlay to buy out Spero feels right. $20/share would serve as a base case yet the greedy faceless owner(s) of all those dark pool purchases on 5/28 and 10/21 will demand much more. My interests are fully aligned with those greedy bastards so I will root them to shoot for the fence and get $50 a share! I want $50 in cash for each of my shares without ever executing a sell order because I trust that GSK will do that for me! Let's all profit from the largesse of the global biopharma gorilla that is GSK. Godspeed to those with conviction!!!
0 · Reply
BEATOFtheMARKET
BEATOFtheMARKET Nov. 11 at 10:07 PM
0 · Reply
mdboss
mdboss Nov. 11 at 11:05 AM
$SPRO Every medical practitioner treating UTIs in the US and around the world will prescribe Tebipenem. The #'s will be massive and so will the GSK buyout price! SHOW ME THE MONEY!!!!!!!!!!!!!!!!!!!! $50???😜
1 · Reply
buyandsold
buyandsold Nov. 11 at 5:41 AM
$SPRO if there is no GSK buyout what would a royalty company pay? Nothing until sales are underway. This stock may do nothing for years as gsk has no incentive to buyout
1 · Reply
DDel
DDel Nov. 10 at 7:50 PM
0 · Reply
mdboss
mdboss Nov. 10 at 2:30 PM
$SPRO We should see cash up and operating expenses down for the quarter. I love it. Not selling a single share until the GSK BO north of $20!
0 · Reply
Drashkawisha
Drashkawisha Nov. 10 at 2:10 PM
$SPRO The GSK partnership ($66M upfront) is the ultimate validation here. Big Pharma doesn't write checks like that unless they see a clear path to approval. Waiting for the PIVOT-PO data to officially clear the CRL hurdle. Patience will be rewarded.
0 · Reply