Spruce Biosciences Inc (SPRB)

$8.82 +0.22 (2.56%)
Market Cap 4.95M
Revenue (ttm) 4.91M
Net Income (ttm) -53.04M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -1,080.24%
Debt to Equity Ratio 0.09
Volume 24,500
Avg Vol 10,359
Day's Range N/A - N/A
Shares Out 562,000.00
Stochastic %K 53%
Beta 2.47
Analysts Hold
Price Target $10.00

Company Profile

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, includ...

Industry: Biotechnology
Sector: Healthcare
Phone: 415 655 4168
Address:
611 Gateway Boulevard, Suite 740, South San Francisco, United States
Vikingsstrade
Vikingsstrade Oct. 3 at 5:50 PM
Merger news on NITO and it barely has 3 million market cap. If people find this, short sellers could get hurt alot on NITO. Small caps have been dead for a while, but NITO gives me hope that short sellers finally get what they deserve! $DEVS $SPRB $SMX $SEAT
0 · Reply
mrtmermer80
mrtmermer80 Oct. 3 at 3:56 PM
$SPRB I am no expert but I can tell you that someone is collecting while holding the SP down. I seen this buying pattern before. Once they are done it will go up significantly.
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LottiedeKitchen
LottiedeKitchen Oct. 3 at 1:46 PM
CVKD Exciting news: Cadrenal Therapeutics Company Webcast @ Lytham Partners Fall 2025 Investor Conference. Watch live here: https://youtu.be/NfPbBjgeIbg?si=2xPvJ2_YJQjHipGa $ASTC $RUMBW $SPRB $QCLS $IPXX
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mcrotary
mcrotary Oct. 3 at 12:53 PM
$SPRB strong
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HouseOfTheDragons
HouseOfTheDragons Oct. 3 at 2:41 AM
Looks like volume & momentum could be shifting in to ASTC! Watchers on ASTC are growing very fast and it could be the potential top runner for this week! Starting its 300% run - keep it on watch! Also watching for breakout: $BURU $CDIO $RDHL $SPRB $VRAX 22
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MoonCowBoy
MoonCowBoy Oct. 2 at 11:52 PM
$SPRB $SMX $MKZR $CLDI \
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1Spartantrade1
1Spartantrade1 Oct. 2 at 6:25 PM
Massive merger news 3 days ago on NITO! NITO has a low share count like TTNP (BTTC) does. TTNP ran 400% today. Can NITO also run 400%? Make sure to take profits. Lets see if NITO halts up today when people realize. $HTCO $EVTV $DEVS $SPRB 🔥
0 · Reply
topstockalerts
topstockalerts Oct. 2 at 11:33 AM
Pre market gainers. $LNKS $LPTX $NBTX $SBLX $SPRB
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topstockalerts
topstockalerts Oct. 2 at 10:30 AM
Pre Market Top Gainers PT2 $LNKS $SPRB $SBLX $NBTX $LPTX
0 · Reply
mrtmermer80
mrtmermer80 Sep. 30 at 4:23 PM
$SPRB Someone manipulating the SP and adding significantly. Another good volume day
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Latest News on SPRB
Spruce Biosciences Resumes Trading on the Nasdaq Capital Market

Sep 15, 2025, 7:00 AM EDT - 19 days ago

Spruce Biosciences Resumes Trading on the Nasdaq Capital Market

Vikingsstrade
Vikingsstrade Oct. 3 at 5:50 PM
Merger news on NITO and it barely has 3 million market cap. If people find this, short sellers could get hurt alot on NITO. Small caps have been dead for a while, but NITO gives me hope that short sellers finally get what they deserve! $DEVS $SPRB $SMX $SEAT
0 · Reply
mrtmermer80
mrtmermer80 Oct. 3 at 3:56 PM
$SPRB I am no expert but I can tell you that someone is collecting while holding the SP down. I seen this buying pattern before. Once they are done it will go up significantly.
0 · Reply
LottiedeKitchen
LottiedeKitchen Oct. 3 at 1:46 PM
CVKD Exciting news: Cadrenal Therapeutics Company Webcast @ Lytham Partners Fall 2025 Investor Conference. Watch live here: https://youtu.be/NfPbBjgeIbg?si=2xPvJ2_YJQjHipGa $ASTC $RUMBW $SPRB $QCLS $IPXX
0 · Reply
mcrotary
mcrotary Oct. 3 at 12:53 PM
$SPRB strong
0 · Reply
HouseOfTheDragons
HouseOfTheDragons Oct. 3 at 2:41 AM
Looks like volume & momentum could be shifting in to ASTC! Watchers on ASTC are growing very fast and it could be the potential top runner for this week! Starting its 300% run - keep it on watch! Also watching for breakout: $BURU $CDIO $RDHL $SPRB $VRAX 22
0 · Reply
MoonCowBoy
MoonCowBoy Oct. 2 at 11:52 PM
$SPRB $SMX $MKZR $CLDI \
0 · Reply
1Spartantrade1
1Spartantrade1 Oct. 2 at 6:25 PM
Massive merger news 3 days ago on NITO! NITO has a low share count like TTNP (BTTC) does. TTNP ran 400% today. Can NITO also run 400%? Make sure to take profits. Lets see if NITO halts up today when people realize. $HTCO $EVTV $DEVS $SPRB 🔥
0 · Reply
topstockalerts
topstockalerts Oct. 2 at 11:33 AM
Pre market gainers. $LNKS $LPTX $NBTX $SBLX $SPRB
0 · Reply
topstockalerts
topstockalerts Oct. 2 at 10:30 AM
Pre Market Top Gainers PT2 $LNKS $SPRB $SBLX $NBTX $LPTX
0 · Reply
mrtmermer80
mrtmermer80 Sep. 30 at 4:23 PM
$SPRB Someone manipulating the SP and adding significantly. Another good volume day
0 · Reply
mrtmermer80
mrtmermer80 Sep. 30 at 3:31 PM
$SPRB Someone is holding this ticker's price very well. Whenever it goes up with buying pressure, someone is selling for less than SP asap.
0 · Reply
beppels
beppels Sep. 30 at 6:36 AM
$NLSP BEPPELS WL 30.09.: - $NLSP, 2.6 $, merger vote yesterday, pr should come out today, pm gapper! ✅ - $APDN, 3.88 $, 1.29 mln float, hit 7.15 $ yesterday on big crypto treasury news! ✅ - $SPRB, 9.74 $, 530 k float, recent uplister from otc, break of 10 $ sends it! ✅ - $SBLX, 4.96 $, 840 k float, bottomed out stablecoin play, 14.65 $ net cash per share! ✅ 👀 🔥 👀
0 · Reply
lookout408
lookout408 Sep. 29 at 6:28 PM
$SPRB come join us going to be epic on the way up....,,,,
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mrtmermer80
mrtmermer80 Sep. 29 at 5:14 PM
$SPRB Very nice high volume on green day. Hoping someone is loading for big day.
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SQUEAKSBANDIT
SQUEAKSBANDIT Sep. 29 at 12:06 AM
$SPRB just in case anyone forgot there are 200MM shares authorized here watch out
1 · Reply
mrtmermer80
mrtmermer80 Sep. 26 at 2:28 PM
$SPRB Pretty much no selling, no buying last few days other than some little short sellers. Lets see when this will move up. It is about time though.
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nUme22
nUme22 Sep. 26 at 12:44 PM
$SPRB seems like done for now.. DEAD
1 · Reply
LQQKER_INSIDER
LQQKER_INSIDER Sep. 25 at 10:37 PM
$SPRB Again, this drug was so wildly successful and loved its first time around, that a WHOPPING grand total of 2 (two) people in the ENTIRE population of mother Earth 🌎, sought compassionate care so that they could remain on the drug after the FDA rejected it the first time.
1 · Reply
Monsters_of_Swing
Monsters_of_Swing Sep. 24 at 5:50 PM
$SPRB place your bets ! how much cash will be left on Sept 30 ?
3 · Reply
jwilk24
jwilk24 Sep. 24 at 3:54 PM
$SPRB added around $7.80’s low $8 average now. She’ll get found
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KradeTing1
KradeTing1 Sep. 24 at 3:40 PM
$SPRB added more in the 7s 🤩
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Monsters_of_Swing
Monsters_of_Swing Sep. 23 at 7:39 PM
$SPRB
0 · Reply