Spruce Biosciences Inc (SPRB)

$70.50 +0.97 (1.39%)
Market Cap 96.72M
Revenue (ttm) 0.00
Net Income (ttm) -38.97M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 37,500
Avg Vol 41,414
Day's Range N/A - N/A
Shares Out 1.37M
Stochastic %K 61%
Beta 3.62
Analysts Strong Sell
Price Target $198.25

Company Profile

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, includ...

Industry: Biotechnology
Sector: Healthcare
Phone: 415 343 5986
Address:
611 Gateway Boulevard, Suite 740, South San Francisco, United States
RadioIsotope25
RadioIsotope25 Apr. 4 at 5:34 PM
$RADX Radiopharm Theranostics ), 2566.66% surge in interest Spruce Biosciences ), 280.31% surge in interest Summit Therapeutics ), 197.53% surge in interest $SPRB $SMMT
1 · Reply
Blink182rulez
Blink182rulez Apr. 1 at 7:33 PM
$SPRB when and what is the next catalyst?
1 · Reply
jchassin3311
jchassin3311 Apr. 1 at 2:03 PM
$SPRB Someone will buy this out by EOY
0 · Reply
Stock_Catcher
Stock_Catcher Mar. 26 at 2:51 AM
Treasure Thursday Watchlist Pt.8 ​ $ASBP $ABVE $WNW $UCAR $SPRB I think Tomorrow Will Be Insanity.
2 · Reply
Stock_Catcher
Stock_Catcher Mar. 26 at 2:50 AM
Treasure Thursday Watchlist Pt.8 ​$ASBP $ABVE $WNW $UCAR $SPRB I think Tomorrow Will Be Insanity
0 · Reply
Few_erish
Few_erish Mar. 25 at 4:26 PM
$SPRB little beast today
0 · Reply
Koa123
Koa123 Mar. 25 at 2:59 PM
$SPRB Pumping, exits and dropping back down to $60-65?
0 · Reply
ignoreo
ignoreo Mar. 25 at 2:34 PM
$SPRB goddamn insider trading. should have known the move up was from dnli leak
0 · Reply
parbv
parbv Mar. 25 at 2:19 PM
$SPRB Bargin of the century here even after the move up.
0 · Reply
jaypatel1242
jaypatel1242 Mar. 25 at 2:05 PM
$SPRB very low float.. can fly like last time!
0 · Reply
Latest News on SPRB
Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates

Mar 9, 2026, 7:05 AM EDT - 27 days ago

Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates

Spruce Biosciences Appoints Dale Hooks, an Accomplished Rare Disease Commercial Leader, as Chief Commercial Officer

Mar 9, 2026, 7:00 AM EDT - 27 days ago

Spruce Biosciences Appoints Dale Hooks, an Accomplished Rare Disease Commercial Leader, as Chief Commercial Officer

Spruce Biosciences to Present at Upcoming Investor Conferences in March

Mar 2, 2026, 4:05 PM EST - 4 weeks ago

Spruce Biosciences to Present at Upcoming Investor Conferences in March

Spruce Biosciences Announces Positive Type B Meetings with U.S. FDA for TA-ERT for the Treatment of Sanfilippo Syndrome Type B (MPS IIIB)

Feb 18, 2026, 7:00 AM EST - 6 weeks ago

Spruce Biosciences Announces Positive Type B Meetings with U.S. FDA for TA-ERT for the Treatment of Sanfilippo Syndrome Type B (MPS IIIB)

Spruce Biosciences to Participate in the Oppenheimer 36th Annual Healthcare Life Sciences Conference

Feb 17, 2026, 4:05 PM EST - 6 weeks ago

Spruce Biosciences to Participate in the Oppenheimer 36th Annual Healthcare Life Sciences Conference

Long-Term Data Presented at the 22nd Annual WORLDSymposium™ Highlights Tralesinidase Alfa Enzyme Replacement Therapy's Potential as the First Disease-Modifying Treatment Option for Sanfilippo Syndrome Type B (MPS IIIB)

Feb 5, 2026, 4:05 PM EST - 2 months ago

Long-Term Data Presented at the 22nd Annual WORLDSymposium™ Highlights Tralesinidase Alfa Enzyme Replacement Therapy's Potential as the First Disease-Modifying Treatment Option for Sanfilippo Syndrome Type B (MPS IIIB)

Spruce Biosciences Adds Regulatory and Clinical Development Expertise to Leadership Team

Feb 3, 2026, 8:00 AM EST - 2 months ago

Spruce Biosciences Adds Regulatory and Clinical Development Expertise to Leadership Team

Spruce Biosciences Announces Data Presentations at the 22nd Annual WORLDSymposium™

Jan 28, 2026, 8:00 AM EST - 2 months ago

Spruce Biosciences Announces Data Presentations at the 22nd Annual WORLDSymposium™

Harbour BioMed Acquires Common Stock in Spruce Biosciences, Deepening Strategic Collaboration

Jan 18, 2026, 7:02 PM EST - 2 months ago

Harbour BioMed Acquires Common Stock in Spruce Biosciences, Deepening Strategic Collaboration

Spruce Biosciences Secures Up to $50 Million in Growth Capital from Avenue Capital

Jan 8, 2026, 8:00 AM EST - 3 months ago

Spruce Biosciences Secures Up to $50 Million in Growth Capital from Avenue Capital

Spruce Biosciences Appoints Proven Pharmaceutical Commercial Leader Keli Walbert to Board of Directors

Dec 15, 2025, 8:00 AM EST - 3 months ago

Spruce Biosciences Appoints Proven Pharmaceutical Commercial Leader Keli Walbert to Board of Directors

Spruce Biosciences Reports Third Quarter 2025 Financial Results and Provides Corporate Updates

Nov 10, 2025, 4:05 PM EST - 5 months ago

Spruce Biosciences Reports Third Quarter 2025 Financial Results and Provides Corporate Updates

Spruce: BTD For TA-ERT For MPS IIIB Could Ignite BLA Submission With Added Bonuses (Rating Upgrade)

Oct 7, 2025, 10:38 AM EDT - 6 months ago

Spruce: BTD For TA-ERT For MPS IIIB Could Ignite BLA Submission With Added Bonuses (Rating Upgrade)

This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug.

Oct 7, 2025, 9:44 AM EDT - 6 months ago

This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug.

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

Oct 6, 2025, 8:00 AM EDT - 6 months ago

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

Spruce Biosciences Resumes Trading on the Nasdaq Capital Market

Sep 15, 2025, 7:00 AM EDT - 7 months ago

Spruce Biosciences Resumes Trading on the Nasdaq Capital Market

RadioIsotope25
RadioIsotope25 Apr. 4 at 5:34 PM
$RADX Radiopharm Theranostics ), 2566.66% surge in interest Spruce Biosciences ), 280.31% surge in interest Summit Therapeutics ), 197.53% surge in interest $SPRB $SMMT
1 · Reply
Blink182rulez
Blink182rulez Apr. 1 at 7:33 PM
$SPRB when and what is the next catalyst?
1 · Reply
jchassin3311
jchassin3311 Apr. 1 at 2:03 PM
$SPRB Someone will buy this out by EOY
0 · Reply
Stock_Catcher
Stock_Catcher Mar. 26 at 2:51 AM
Treasure Thursday Watchlist Pt.8 ​ $ASBP $ABVE $WNW $UCAR $SPRB I think Tomorrow Will Be Insanity.
2 · Reply
Stock_Catcher
Stock_Catcher Mar. 26 at 2:50 AM
Treasure Thursday Watchlist Pt.8 ​$ASBP $ABVE $WNW $UCAR $SPRB I think Tomorrow Will Be Insanity
0 · Reply
Few_erish
Few_erish Mar. 25 at 4:26 PM
$SPRB little beast today
0 · Reply
Koa123
Koa123 Mar. 25 at 2:59 PM
$SPRB Pumping, exits and dropping back down to $60-65?
0 · Reply
ignoreo
ignoreo Mar. 25 at 2:34 PM
$SPRB goddamn insider trading. should have known the move up was from dnli leak
0 · Reply
parbv
parbv Mar. 25 at 2:19 PM
$SPRB Bargin of the century here even after the move up.
0 · Reply
jaypatel1242
jaypatel1242 Mar. 25 at 2:05 PM
$SPRB very low float.. can fly like last time!
0 · Reply
SannieVerraderlijk
SannieVerraderlijk Mar. 25 at 1:27 PM
$SPRB Up on $DNLI approval
0 · Reply
SannieVerraderlijk
SannieVerraderlijk Mar. 25 at 1:21 PM
$SPRB LFG
0 · Reply
DennisTex
DennisTex Mar. 25 at 1:18 PM
$SPRB Oh… okay then 😅
0 · Reply
Stock_Catcher
Stock_Catcher Mar. 25 at 1:13 PM
$SPRB Thin One
0 · Reply
ignoreo
ignoreo Mar. 25 at 12:53 AM
$SPRB out with everything but a small position
0 · Reply
SannieVerraderlijk
SannieVerraderlijk Mar. 24 at 1:24 PM
$SPRB In with a small position
0 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Mar. 20 at 9:20 PM
$SPRB Tonight's SEC filing is meaningless. It's in reference to a drug that is NOT sprb's lead drug.
0 · Reply
FilingTracker
FilingTracker Mar. 20 at 9:07 PM
$SPRB Terminated agreement with Kaken Pharmaceutical Co., Ltd.: https://www.sec.gov/Archives/edgar/data/1683553/000119312526117888/sprb-20260316.htm
0 · Reply
Midori_Hachi
Midori_Hachi Mar. 18 at 4:39 PM
$SPRB
0 · Reply
BladeKingShadowLordX
BladeKingShadowLordX Mar. 16 at 11:18 PM
$ALDX HAHA sHrekli ! U pumped dog $SPRB now it's my TURD Watch me PUMp this BABy
0 · Reply
RickyIsRich
RickyIsRich Mar. 16 at 3:12 PM
$SPRB wonderful drug FDA Q4 2026 potential $500 stock slam dunk buying
1 · Reply
Jakcofalltrades
Jakcofalltrades Mar. 16 at 2:28 AM
$SPRB who’s buying this shit
0 · Reply