Market Cap 74.12M
Revenue (ttm) 0.00
Net Income (ttm) -38.97M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 59,400
Avg Vol 67,440
Day's Range N/A - N/A
Shares Out 1.37M
Stochastic %K 13%
Beta 3.62
Analysts Strong Sell
Price Target $198.25

Company Profile

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, includ...

Industry: Biotechnology
Sector: Healthcare
Phone: 415 343 5986
Address:
611 Gateway Boulevard, Suite 740, South San Francisco, United States
NasdaqPulse
NasdaqPulse Apr. 24 at 3:07 PM
$SPRB — one of the cleanest asymmetric small-cap biotech setups on my radar right now. 👉Click to view @NasdaqPulse for timely updates amid the volatility. They just locked in a ~$60M raise, which removes near-term funding risk and gives them a full runway into multiple catalysts over the next 12 months. That alone resets the downside profile. Meanwhile, market cap still sitting around ~$140M… that disconnect is exactly where traders get paid. You’ve got high-profile eyes like Martin Shkreli calling for extreme upside (even after dilution), but even stripping that out — a more grounded scenario still points to multi-bagger potential if execution lands. Low float + fresh capital + upcoming data = volatility expansion setup. And don’t ignore the M&A angle — this is the type of beaten-down, recapitalized biotech that gets scooped when sentiment flips. Not chasing — but definitely stalking this one into catalysts. Risk/reward skew is hard to ignore.
0 · Reply
Stockhunter008
Stockhunter008 Apr. 24 at 3:50 AM
$CMMB $SPRB Compare CMMB's BTD prospects to those of SPRB prior to their BTD grant
0 · Reply
Roaring_Capybara
Roaring_Capybara Apr. 22 at 5:35 PM
$SPRB Merck takeover: https://maandhunter.substack.com/p/inbx-the-keytruda-defense-play-just
1 · Reply
parbv
parbv Apr. 22 at 2:02 PM
$SPRB My issue is how do you trust management to not do another garbage raise that screws shareholders. I've been modeling the PRV as being worth 150 million, but they'll probably sell it for 25 instead
2 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 3:28 AM
Did you intentionally cut off the last line of Shkreli's twitter $SPRB convo? In the last line, which you left out, shkreli gives $SPRB a price target of $225/share (see my screenshot below, which includes the part you left out). Shkreli's new price target for sprb is a FOUR BAGGER. So, sprb at 52\share is a SCREAMING BUY. Shizz is gonna run so hard over next few weeks.
1 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 3:00 AM
@ShakeThatMoneyMaker Nice try. You’re posting total nonsense. Give us an actual model. What’s your model? You’re just going wave your hands. You won’t give us a model bc any honest model shows that $SPRB at 52/share is massively undervalued.
0 · Reply
ShakeThatMoneyMaker
ShakeThatMoneyMaker Apr. 22 at 2:32 AM
$SPRB dilution kills all bios.
0 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 1:34 AM
At $52/share $SPRB, I’m all in. 1. The voucher alone is worth 57/share. 2. They now have 48/share in cash. 3. The asset is worth anywhere from 118/share (absolute worst case) to 236/share. Add that up. $SPRB is worth at least 223/share, if not 341/share. 52/share is a screaming buy. Stock will be up 50% in next 90 days. At least.
2 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 1:18 AM
0 · Reply
Jakcofalltrades
Jakcofalltrades Apr. 21 at 11:28 PM
$SPRB this junk is going to $25 soon
0 · Reply
Latest News on SPRB
Spruce Biosciences Resumes Trading on the Nasdaq Capital Market

Sep 15, 2025, 7:00 AM EDT - 7 months ago

Spruce Biosciences Resumes Trading on the Nasdaq Capital Market


Spruce Biosciences Transcript: Investor Update

Apr 15, 2025, 8:30 AM EDT - 1 year ago

Spruce Biosciences Transcript: Investor Update


Spruce Biosciences Earnings Call Transcript: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spruce Biosciences Earnings Call Transcript: Q4 2023


NasdaqPulse
NasdaqPulse Apr. 24 at 3:07 PM
$SPRB — one of the cleanest asymmetric small-cap biotech setups on my radar right now. 👉Click to view @NasdaqPulse for timely updates amid the volatility. They just locked in a ~$60M raise, which removes near-term funding risk and gives them a full runway into multiple catalysts over the next 12 months. That alone resets the downside profile. Meanwhile, market cap still sitting around ~$140M… that disconnect is exactly where traders get paid. You’ve got high-profile eyes like Martin Shkreli calling for extreme upside (even after dilution), but even stripping that out — a more grounded scenario still points to multi-bagger potential if execution lands. Low float + fresh capital + upcoming data = volatility expansion setup. And don’t ignore the M&A angle — this is the type of beaten-down, recapitalized biotech that gets scooped when sentiment flips. Not chasing — but definitely stalking this one into catalysts. Risk/reward skew is hard to ignore.
0 · Reply
Stockhunter008
Stockhunter008 Apr. 24 at 3:50 AM
$CMMB $SPRB Compare CMMB's BTD prospects to those of SPRB prior to their BTD grant
0 · Reply
Roaring_Capybara
Roaring_Capybara Apr. 22 at 5:35 PM
$SPRB Merck takeover: https://maandhunter.substack.com/p/inbx-the-keytruda-defense-play-just
1 · Reply
parbv
parbv Apr. 22 at 2:02 PM
$SPRB My issue is how do you trust management to not do another garbage raise that screws shareholders. I've been modeling the PRV as being worth 150 million, but they'll probably sell it for 25 instead
2 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 3:28 AM
Did you intentionally cut off the last line of Shkreli's twitter $SPRB convo? In the last line, which you left out, shkreli gives $SPRB a price target of $225/share (see my screenshot below, which includes the part you left out). Shkreli's new price target for sprb is a FOUR BAGGER. So, sprb at 52\share is a SCREAMING BUY. Shizz is gonna run so hard over next few weeks.
1 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 3:00 AM
@ShakeThatMoneyMaker Nice try. You’re posting total nonsense. Give us an actual model. What’s your model? You’re just going wave your hands. You won’t give us a model bc any honest model shows that $SPRB at 52/share is massively undervalued.
0 · Reply
ShakeThatMoneyMaker
ShakeThatMoneyMaker Apr. 22 at 2:32 AM
$SPRB dilution kills all bios.
0 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 1:34 AM
At $52/share $SPRB, I’m all in. 1. The voucher alone is worth 57/share. 2. They now have 48/share in cash. 3. The asset is worth anywhere from 118/share (absolute worst case) to 236/share. Add that up. $SPRB is worth at least 223/share, if not 341/share. 52/share is a screaming buy. Stock will be up 50% in next 90 days. At least.
2 · Reply
TheGodsMustBeCrazy
TheGodsMustBeCrazy Apr. 22 at 1:18 AM
0 · Reply
Jakcofalltrades
Jakcofalltrades Apr. 21 at 11:28 PM
$SPRB this junk is going to $25 soon
0 · Reply
strategicmind
strategicmind Apr. 21 at 11:08 PM
$SPRB thank you BioMarin for this asset! Even with the dillution, market cap of a billion is good estimate doing a DCF. Which roughly implies 6X from these prices 😉. I’ll take even half that
0 · Reply
strategicmind
strategicmind Apr. 21 at 9:26 PM
$SPRB Bought some. Very good risk/ reward ratio here IMO. Voucher alone is worth 2X more than market cap right now.
0 · Reply
thedavidsonny
thedavidsonny Apr. 21 at 9:01 PM
$SPRB HOPEFULLY IT RECOVERS 😢 PLAN B CTNT ON 🔥 ... GET MONEY BACK
0 · Reply
il_perito
il_perito Apr. 21 at 7:56 PM
$SPRB Buy while you can. This is a 5X thing
1 · Reply
Bill_S_Preston_San_Dimas
Bill_S_Preston_San_Dimas Apr. 21 at 7:09 PM
$SPRB found my girls purse, stole a few coins and bought more $SPRB
0 · Reply
1AMBITIOUSSAVAGE
1AMBITIOUSSAVAGE Apr. 21 at 6:52 PM
$PMAX $SPRB 👏🏼 CMCT 👀 EXTREMELY
0 · Reply
il_perito
il_perito Apr. 21 at 5:57 PM
$SPRB I am in. Small position though 🤙
0 · Reply
IjustTradeiT
IjustTradeiT Apr. 21 at 4:39 PM
$SPRB Should I cover my 200s yet? I think I'll wait till 5
1 · Reply
neelsen01
neelsen01 Apr. 21 at 3:45 PM
$SPRB $50 level on watch..,
0 · Reply
BigWaveOperator
BigWaveOperator Apr. 21 at 2:10 PM
$SPRB just another POS bio dilution machine.
0 · Reply
Aawilliam2003
Aawilliam2003 Apr. 21 at 2:01 PM
$SPRB total kick in the nuts. I think there is just a ton or uncertainty here so they had to give it away give it away now
1 · Reply
stockanalysis_
stockanalysis_ Apr. 21 at 1:25 PM
Premarket Losers: $SOWG $ALBT $TOVX $SPRB $AMST Download this screener: https://stockanalysis.com/markets/premarket/losers/?ref=saveontrading
0 · Reply