Jul. 18 at 5:21 PM
$QSI $NAUT Comparing affinity probes (NAUT) to direct protein sequencing (QSI) is like comparing a bicycle to a Ferrari.
Nautilus is literally making a 'best guess' by pattern matching against a database. Why would a researcher settle for a best guess with Voyager (NAUT) when they can perform direct de novo sequencing of proteins at amino acid resolution with Proteus (QSI)? Answer: they won't.
This is what happens when you're five years late shipping your platform. Nautilus has been lapped before they even leave the starting gate.
Voyager may be fine dealing with whole, intact proteins, but that's not the real world. Scientists need the ability to break small sample protein fragments into peptides and bind them to amino acids to accurately identify specific mutations, post-translational modifications and variants. That's what Proteus does, and that's where the breakthroughs will be made in drug discovery, next generation therapeutics, vaccine development, etc.