Biotechlineup
Sep 30, 12:59 AM
$BCTX The Phase 2 study patients who were DHT+ lived more than double the length of time compared to those who were DHT - , 11.3 months vs 4.7 months
By saying this is happening in the majority of the current Phase 3 patients, management is heavily implying that most patients on the active drug arm are successfully generating the protective immune response required to extend their lives. Control Arm is of course DHT- . Unfortunately for the control arm is not doing well. That’s 2+2 speculation if management stated they are on track for Dec then the majority must be in the control arm and therefore high likelihood of a .6 HR?
https://briacell.com/briacell-presents-outstanding-phase-2-survival-promising-phase-3-clinical-data-at-sabcs-2025/
<>Positive Delayed Type Hypersensitivity (DTH) may be key predictor of clinical benefit as median overall survival (OS) was significantly (P=0.0001) higher in patients who were DTH+ (11.3 months) vs those who were DTH- (4.7 months).>>
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