Nov. 7 at 8:34 PM
$BCTX The data is good, but (as they said beforehand) it is just pre-clinical modeling data to support the advancement into human trials. Very much in line with previous posters, showing the tell-tale increase in immune activation and expression of immune-boosting cytokines. Nothing Earth-shattering was expected pr presented.
Notable that the therapy not only boosts the immune response, but also maintains normal (rather than dysfunctional) checkpoint and immune-modulating expressions. An important consideration when boosting the immune response (especially in combo with CPI), is that the immune system retains the ability to down-regulate or turn it off at some point, to avoid autoimmune reactions.
