Market Cap 78.45M
Revenue (ttm) 0.00
Net Income (ttm) -24.59M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 457,349
Avg Vol 1,937,236
Day's Range N/A - N/A
Shares Out 26.50M
Stochastic %K 33%
Beta 1.46
Analysts Strong Sell
Price Target $11.67

Company Profile

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 2/3 to treat alzheimer's disease, as well as in phase 3 to treat parkinson's disease; and is in phase 2 clinical trial to treat lewy body dementia. It also develops ANVS405, which is in phase 2 and 3 clinical trials for the treatment of traumatic brain injury and/or stroke; and ANVS301, which finished phas...

Industry: Biotechnology
Sector: Healthcare
Phone: 484 875 3192
Address:
101 Lindenwood Drive, Suite 225, Malvern, United States
StMichaelTwits
StMichaelTwits Jan. 29 at 2:05 AM
$ANVS Patients from the trial on the call. Amazing. Have to take them at their word. It is working, and they want to get on the new trial. But.. the money's & timing. For now, unless any news, this is dropping I would imagine..maybe some Alz update move it up or hold it at a certain level..Either way I am holding. Future.. All depends on the readout from the 6 months after final enrollment. She stated March or April latest. She will hopefully keep her word. We will find out soon enough. If readouts are good to great, we will have some big interest for financing..Without the financing, it will have to be through offering..If news is great, expect SP over $7+ then an offering but not as much hopefully. Game plan, if offering, wait a week or so after to load. I will and large..imo.
1 · Reply
donemedirty
donemedirty Jan. 29 at 2:00 AM
$ANVS Sorry, hire a pr person
0 · Reply
donemedirty
donemedirty Jan. 29 at 1:58 AM
$ANVS bullshit where the news or the update pd.Maria go high a pr person. Stay in the office do you research.
0 · Reply
5StarTrader
5StarTrader Jan. 29 at 12:46 AM
$ANVS Well, to put things in perspective, just a few days ago clinical stage CRVS was trading at $6 pps when they announced the results of a phase 1 safety study on an eczema drug showing it to be safe and begining to separate from placebo showing a little improvement after 8 days. The stock soared to $26 with a MC of $2 Billion with PT’s raised to $42-$46. They immediately had a pre planned stock offering for $175 million curing their cash shortage. The TAM for CRVS’s drug candidate is not as large as ANVS TAM. ANVS candidate is at a more advanced stage of development with multiple indications and has a FDA endorsed pathway for approval. Yet, the MC of ANVS is only $80 million. The risk/reward with ANVS drug, which is not only safe, but has been shown to be significantly effective. Plus it’s substantially closer to getting FDA approval. Any number of near term events will radically change the MC & share price for investors who hold a position in the stock.
3 · Reply
dwayne09
dwayne09 Jan. 29 at 12:37 AM
$ANVS Maria tells it as it is. 6 months 18 monyhs study can take a year to 24 months to complete. Nothing wrong with that. She believes in butanetap, and all the results so far supports it. 80 million MC for a potentially disease modifying drug. not a bad deal at all, just matter if you have the patience or not.
0 · Reply
Hankjessie
Hankjessie Jan. 29 at 12:01 AM
$ANVS this bozo ceo is and has always been a fraud.
0 · Reply
junkjar291
junkjar291 Jan. 28 at 11:59 PM
$ANVS CEO need to stop talking about billion-dollar market, she can't even get one million to run her trial. Most of the people on the call are there to learn about trial so they can join for free, but they don't realize company is broke and she can't even get her current trial enrolled due to funding issue. This is a POS.
1 · Reply
BIOMILITIA
BIOMILITIA Jan. 28 at 11:50 PM
$ANVS Maria and these investor conferences are nothing but a sad attempt to raise the share price but end up tanking it. Sad.
1 · Reply
EgretMan
EgretMan Jan. 28 at 11:30 PM
$ANVS This is going to crash hard tomorrow!!!
1 · Reply
ppl_first
ppl_first Jan. 28 at 11:26 PM
$ANVS what worries me most is I’ve seen all of those slides before. There is literally nothing new. They were supposed to be 100% enrolled. No partner talk whatsoever. No FDA hard dates. All just the same thing as the last several presentation decks. Change my mind.
2 · Reply
Latest News on ANVS
Annovis to Host Corporate Update Webinar on January 28, 2026

Dec 16, 2025, 8:00 AM EST - 6 weeks ago

Annovis to Host Corporate Update Webinar on January 28, 2026


Annovis Announces Two Presentations at the CTAD 2025 Conference

Nov 24, 2025, 8:00 AM EST - 2 months ago

Annovis Announces Two Presentations at the CTAD 2025 Conference


Annovis Appoints Mark Guerin as Chief Financial Officer

Sep 25, 2025, 7:30 AM EDT - 4 months ago

Annovis Appoints Mark Guerin as Chief Financial Officer


Annovis Completes Full Patent Transfer to Crystal Buntanetap

Aug 7, 2025, 8:00 AM EDT - 6 months ago

Annovis Completes Full Patent Transfer to Crystal Buntanetap


Annovis to Attend the AAIC 2025 with Four Poster Presentations

Jun 26, 2025, 8:00 AM EDT - 7 months ago

Annovis to Attend the AAIC 2025 with Four Poster Presentations


Annovis to Host Webinar and Live Q&A on June 24, 2025

Jun 5, 2025, 8:00 AM EDT - 8 months ago

Annovis to Host Webinar and Live Q&A on June 24, 2025


Annovis Bio Appoints Hui Liu as Director of Biostatistics

Apr 29, 2025, 8:00 AM EDT - 9 months ago

Annovis Bio Appoints Hui Liu as Director of Biostatistics


Annovis to Attend AD/PD™ 2025 with Extensive Scientific Program

Mar 25, 2025, 8:00 AM EDT - 11 months ago

Annovis to Attend AD/PD™ 2025 with Extensive Scientific Program


Annovis to Host Patients' Live Forum on February 27, 2025

Feb 19, 2025, 8:30 AM EST - 1 year ago

Annovis to Host Patients' Live Forum on February 27, 2025


Annovis Bio, Inc. Announces Proposed Public Offering

Jan 31, 2025, 8:14 PM EST - 1 year ago

Annovis Bio, Inc. Announces Proposed Public Offering


/C O R R E C T I O N -- Today's Marketplace/

Dec 4, 2024, 2:21 PM EST - 1 year ago

/C O R R E C T I O N -- Today's Marketplace/


Annovis stock more than doubled on Tuesday: what happened?

Jul 2, 2024, 4:13 PM EDT - 1 year ago

Annovis stock more than doubled on Tuesday: what happened?


Annovis Announces New Publication in a Peer-Reviewed Journal

May 21, 2024, 7:30 AM EDT - 1 year ago

Annovis Announces New Publication in a Peer-Reviewed Journal


StMichaelTwits
StMichaelTwits Jan. 29 at 2:05 AM
$ANVS Patients from the trial on the call. Amazing. Have to take them at their word. It is working, and they want to get on the new trial. But.. the money's & timing. For now, unless any news, this is dropping I would imagine..maybe some Alz update move it up or hold it at a certain level..Either way I am holding. Future.. All depends on the readout from the 6 months after final enrollment. She stated March or April latest. She will hopefully keep her word. We will find out soon enough. If readouts are good to great, we will have some big interest for financing..Without the financing, it will have to be through offering..If news is great, expect SP over $7+ then an offering but not as much hopefully. Game plan, if offering, wait a week or so after to load. I will and large..imo.
1 · Reply
donemedirty
donemedirty Jan. 29 at 2:00 AM
$ANVS Sorry, hire a pr person
0 · Reply
donemedirty
donemedirty Jan. 29 at 1:58 AM
$ANVS bullshit where the news or the update pd.Maria go high a pr person. Stay in the office do you research.
0 · Reply
5StarTrader
5StarTrader Jan. 29 at 12:46 AM
$ANVS Well, to put things in perspective, just a few days ago clinical stage CRVS was trading at $6 pps when they announced the results of a phase 1 safety study on an eczema drug showing it to be safe and begining to separate from placebo showing a little improvement after 8 days. The stock soared to $26 with a MC of $2 Billion with PT’s raised to $42-$46. They immediately had a pre planned stock offering for $175 million curing their cash shortage. The TAM for CRVS’s drug candidate is not as large as ANVS TAM. ANVS candidate is at a more advanced stage of development with multiple indications and has a FDA endorsed pathway for approval. Yet, the MC of ANVS is only $80 million. The risk/reward with ANVS drug, which is not only safe, but has been shown to be significantly effective. Plus it’s substantially closer to getting FDA approval. Any number of near term events will radically change the MC & share price for investors who hold a position in the stock.
3 · Reply
dwayne09
dwayne09 Jan. 29 at 12:37 AM
$ANVS Maria tells it as it is. 6 months 18 monyhs study can take a year to 24 months to complete. Nothing wrong with that. She believes in butanetap, and all the results so far supports it. 80 million MC for a potentially disease modifying drug. not a bad deal at all, just matter if you have the patience or not.
0 · Reply
Hankjessie
Hankjessie Jan. 29 at 12:01 AM
$ANVS this bozo ceo is and has always been a fraud.
0 · Reply
junkjar291
junkjar291 Jan. 28 at 11:59 PM
$ANVS CEO need to stop talking about billion-dollar market, she can't even get one million to run her trial. Most of the people on the call are there to learn about trial so they can join for free, but they don't realize company is broke and she can't even get her current trial enrolled due to funding issue. This is a POS.
1 · Reply
BIOMILITIA
BIOMILITIA Jan. 28 at 11:50 PM
$ANVS Maria and these investor conferences are nothing but a sad attempt to raise the share price but end up tanking it. Sad.
1 · Reply
EgretMan
EgretMan Jan. 28 at 11:30 PM
$ANVS This is going to crash hard tomorrow!!!
1 · Reply
ppl_first
ppl_first Jan. 28 at 11:26 PM
$ANVS what worries me most is I’ve seen all of those slides before. There is literally nothing new. They were supposed to be 100% enrolled. No partner talk whatsoever. No FDA hard dates. All just the same thing as the last several presentation decks. Change my mind.
2 · Reply
dwayne09
dwayne09 Jan. 28 at 11:05 PM
$ANVS AD study enrollment complete by April, 1st readout may come Oct-Dec, Maria is confident the results will be good. Company will eventually need to raise money, but current 19 million will see us through the fall, by that time the preliminary results sould be ready and company will raise money at much higher prices. few hundred million MC is easily attainable.
2 · Reply
MomoMrCow
MomoMrCow Jan. 28 at 10:45 PM
$ANVS I still must question though. Why the heavy insider buys if there are no material updates, PRs, or 8-ks + delayed enrollment and limited funding?
0 · Reply
MomoMrCow
MomoMrCow Jan. 28 at 10:39 PM
$ANVS stock price and investing out the way though. A lot of people seem to have benefited from the drug and are eager to enroll their loved ones :)
0 · Reply
MomoMrCow
MomoMrCow Jan. 28 at 10:37 PM
$ANVS drug is really promising. But it’s just a ways off…
1 · Reply
StMichaelTwits
StMichaelTwits Jan. 28 at 10:36 PM
$ANVS The Zoom meeting will be on their website later today I think.. Drug seems to be really good..But they need the financing to finish off the 18 month.. After the offering..which I think is later this fall..is the time to load..usually to load up a week or two after the offering. There could still be some major bio company come in to finance after the 6 month review, if the results are wicked..but even then its a 50/50 shot of monies from the major bio company;.
0 · Reply
RoyalPurp
RoyalPurp Jan. 28 at 10:28 PM
$ANVS More time to load, you say? At these single digits?!
0 · Reply
StMichaelTwits
StMichaelTwits Jan. 28 at 10:25 PM
$ANVS They are going to need financing..by the looks of it, through shares...No help from big bios until they finish the 18 month trial as per maria..that was me asking. My bets..an offering is coming around 7 months away. Only way looks like if after 6 months update of the 18 month, some really good results, should move the stock higher, but my bets an offering after that date.
0 · Reply
To_De_Moon
To_De_Moon Jan. 28 at 9:54 PM
$ANVS no full 100% Alzheimer enrollment till April
2 · Reply
ppl_first
ppl_first Jan. 28 at 9:53 PM
$ANVS Summary: 4 studies for cognition. Efficacy in all four groups. Aricept, the standard of care, works 6 months and the benefit stops. Disease modification drugs on the market like Leqembi and Kisunla improve but not much over the natural progression. Our hero Buntanetap is 2.5x better than standard of care. They are pursuing the study for 18 months to find out if it is in fact disease-modifying. In animals, it works - reverses the cognition over 9-12 months. If so, this sells into a $100B market and they expect 20% of that. Full recruitment in spring, FDA agrees with the PD study, though there are no guidelines for testing because there is currently no drug on the market.
1 · Reply
StMichaelTwits
StMichaelTwits Jan. 28 at 9:52 PM
$ANVS Why no BLA for this since no other drug out there for PDD. ?? If the drug is exceptionally good, why not discuss Accelerated Approval or Priority Review? my last question.
1 · Reply
StMichaelTwits
StMichaelTwits Jan. 28 at 9:49 PM
$ANVS PDD.. After fda letter last week and response.. Doing a trial for PDD..no drug out there for this so looks like a fda dude will be involved? Next month, they will have a better answer.
0 · Reply
junkjar291
junkjar291 Jan. 28 at 9:49 PM
$ANVS Not much progress on enrollment on AD P3, it is stalled at 40%. This is very bad, they will run out of money before they recruit. Don't expect any 6month data this year. Type c meeting never happened, they onlyt received guidance on PDD, nothing else. Total POS
0 · Reply