Market Cap 109.46M
Revenue (ttm) 0.00
Net Income (ttm) -24.59M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,044,200
Avg Vol 2,268,706
Day's Range N/A - N/A
Shares Out 26.50M
Stochastic %K 38%
Beta 1.49
Analysts Strong Sell
Price Target $11.67

Company Profile

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 2/3 to treat alzheimer's disease, as well as in phase 3 to treat parkinson's disease; and is in phase 2 clinical trial to treat lewy body dementia. It also develops ANVS405, which is in phase 2 and 3 clinical trials for the treatment of traumatic brain injury and/or stroke; and ANVS301, which finished phas...

Industry: Biotechnology
Sector: Healthcare
Phone: 484 875 3192
Address:
101 Lindenwood Drive, Suite 225, Malvern, United States
dwayne09
dwayne09 Dec. 13 at 12:46 AM
$ANVS Maria has emphasized the subgroups and how it may impacted the effectiveness of Butanetap, or any other drug. Lot folks said that is BS. Well, today's article basically suggest BP agrees. However, BP will not own up to this because they are not the front runner in this catagory and they have nothing to gain.
1 · Reply
ScottHopko
ScottHopko Dec. 12 at 11:09 PM
$ANVS Great day! On Friday, December 12th, ANVS moved up 8.97% while volume shrunk to 0.5× the usual levels. Multiple bullish signals emerged — Crossed Above 20 DMA, Bullish Engulfing, New Uptrend & Directional Movement Crossover Bullish — suggesting potential strength ahead. Key support levels exist at 3.81, 3.49 & 3.28, with resistance at 4.34, 4.55 & 4.87.
0 · Reply
RunnerSignals
RunnerSignals Dec. 12 at 9:45 PM
Morning Red Turns Afternoon Green $COGT $STIM $VERA $ANVS stumbled out the gate but soared into the close. market warriors showing how to flip the script in style
0 · Reply
stockpro27
stockpro27 Dec. 12 at 8:10 PM
$ANVS you are probably right. That’s why tech is down lately because the paid trolls are pushing false narratives like OpenAI is delaying data centers into 2028, which company management denied and Broadcom, which beat earnings estimates billed as not good enough by the analysts.
0 · Reply
stockpro27
stockpro27 Dec. 12 at 7:58 PM
$ANVS is Hoffman buying today?
1 · Reply
kshonstocks
kshonstocks Dec. 12 at 7:56 PM
$ANVS holding 20 dma
0 · Reply
AntonioChigurh
AntonioChigurh Dec. 12 at 7:53 PM
$ANVS $AVXL Missling WOULD NEVER now that it’s officially rejected by EMA
0 · Reply
dayisthebest
dayisthebest Dec. 12 at 7:50 PM
$AVXL Like that $ANVS insiders bought shares. what have our insider done?
0 · Reply
StMichaelTwits
StMichaelTwits Dec. 12 at 7:42 PM
$ANVS Maria's quote below is so true. My fatherinlaws doc said that he had shaking left hand because of his old age..(doc = mamaluke) 2nd opinion doc..he found Parkinsons.
1 · Reply
pedmac2000
pedmac2000 Dec. 12 at 6:41 PM
$ANVS anyone watching this ??
2 · Reply
Latest News on ANVS
Annovis Announces Two Presentations at the CTAD 2025 Conference

Nov 24, 2025, 8:00 AM EST - 19 days ago

Annovis Announces Two Presentations at the CTAD 2025 Conference


Annovis Appoints Mark Guerin as Chief Financial Officer

Sep 25, 2025, 7:30 AM EDT - 2 months ago

Annovis Appoints Mark Guerin as Chief Financial Officer


Annovis Completes Full Patent Transfer to Crystal Buntanetap

Aug 7, 2025, 8:00 AM EDT - 4 months ago

Annovis Completes Full Patent Transfer to Crystal Buntanetap


Annovis to Attend the AAIC 2025 with Four Poster Presentations

Jun 26, 2025, 8:00 AM EDT - 6 months ago

Annovis to Attend the AAIC 2025 with Four Poster Presentations


Annovis to Host Webinar and Live Q&A on June 24, 2025

Jun 5, 2025, 8:00 AM EDT - 6 months ago

Annovis to Host Webinar and Live Q&A on June 24, 2025


Annovis Bio Appoints Hui Liu as Director of Biostatistics

Apr 29, 2025, 8:00 AM EDT - 8 months ago

Annovis Bio Appoints Hui Liu as Director of Biostatistics


Annovis to Host Patients' Live Forum on February 27, 2025

Feb 19, 2025, 8:30 AM EST - 10 months ago

Annovis to Host Patients' Live Forum on February 27, 2025


Annovis Bio, Inc. Announces Proposed Public Offering

Jan 31, 2025, 8:14 PM EST - 11 months ago

Annovis Bio, Inc. Announces Proposed Public Offering


/C O R R E C T I O N -- Today's Marketplace/

Dec 4, 2024, 2:21 PM EST - 1 year ago

/C O R R E C T I O N -- Today's Marketplace/


Annovis stock more than doubled on Tuesday: what happened?

Jul 2, 2024, 4:13 PM EDT - 1 year ago

Annovis stock more than doubled on Tuesday: what happened?


Annovis Announces New Publication in a Peer-Reviewed Journal

May 21, 2024, 7:30 AM EDT - 1 year ago

Annovis Announces New Publication in a Peer-Reviewed Journal


dwayne09
dwayne09 Dec. 13 at 12:46 AM
$ANVS Maria has emphasized the subgroups and how it may impacted the effectiveness of Butanetap, or any other drug. Lot folks said that is BS. Well, today's article basically suggest BP agrees. However, BP will not own up to this because they are not the front runner in this catagory and they have nothing to gain.
1 · Reply
ScottHopko
ScottHopko Dec. 12 at 11:09 PM
$ANVS Great day! On Friday, December 12th, ANVS moved up 8.97% while volume shrunk to 0.5× the usual levels. Multiple bullish signals emerged — Crossed Above 20 DMA, Bullish Engulfing, New Uptrend & Directional Movement Crossover Bullish — suggesting potential strength ahead. Key support levels exist at 3.81, 3.49 & 3.28, with resistance at 4.34, 4.55 & 4.87.
0 · Reply
RunnerSignals
RunnerSignals Dec. 12 at 9:45 PM
Morning Red Turns Afternoon Green $COGT $STIM $VERA $ANVS stumbled out the gate but soared into the close. market warriors showing how to flip the script in style
0 · Reply
stockpro27
stockpro27 Dec. 12 at 8:10 PM
$ANVS you are probably right. That’s why tech is down lately because the paid trolls are pushing false narratives like OpenAI is delaying data centers into 2028, which company management denied and Broadcom, which beat earnings estimates billed as not good enough by the analysts.
0 · Reply
stockpro27
stockpro27 Dec. 12 at 7:58 PM
$ANVS is Hoffman buying today?
1 · Reply
kshonstocks
kshonstocks Dec. 12 at 7:56 PM
$ANVS holding 20 dma
0 · Reply
AntonioChigurh
AntonioChigurh Dec. 12 at 7:53 PM
$ANVS $AVXL Missling WOULD NEVER now that it’s officially rejected by EMA
0 · Reply
dayisthebest
dayisthebest Dec. 12 at 7:50 PM
$AVXL Like that $ANVS insiders bought shares. what have our insider done?
0 · Reply
StMichaelTwits
StMichaelTwits Dec. 12 at 7:42 PM
$ANVS Maria's quote below is so true. My fatherinlaws doc said that he had shaking left hand because of his old age..(doc = mamaluke) 2nd opinion doc..he found Parkinsons.
1 · Reply
pedmac2000
pedmac2000 Dec. 12 at 6:41 PM
$ANVS anyone watching this ??
2 · Reply
Itsybitsybeanbag
Itsybitsybeanbag Dec. 12 at 6:14 PM
$ANVS Another bites it Europes EMA's Committee for Medicinal Products for Human Use (CHMP) recommended denying marketing approval for blarcamesine (Anavex 2-73) for early Alzheimer's, citing insufficient effectiveness/safety data and impurity issues.
0 · Reply
MomoMrCow
MomoMrCow Dec. 12 at 4:20 PM
$ANVS Algos picking up because of article or is it real buyers? 👀
2 · Reply
doyoujetset
doyoujetset Dec. 12 at 4:18 PM
$ANVS healthy consolidation on the middle Bollinger band. Noise always gets loud when retracing or in the trough⏳
1 · Reply
StMichaelTwits
StMichaelTwits Dec. 12 at 4:17 PM
$ANVS https://www.reuters.com/business/healthcare-pharmaceuticals/alzheimers-drug-hunt-learns-cancer-fights-multi-target-playbook-2025-12-12/"Annovis Bio (ANVS.N), opens new tab is developing a drug with multiple targets. Its experimental drug buntanetap, now in Phase 3 testing, targets amyloid, tau and two other neurotoxic proteins. Annovis CEO Maria Maccecchini said an earlier study failed because inadequate screening allowed for many participants who did not actually have Alzheimer's. "When we eliminated them by blood testing, then we got highly statistically significant cognitive improvement," she said. "We assume that doctors know what's Alzheimer's and Parkinson's... but maybe they don't."
0 · Reply
LionNoRichy
LionNoRichy Dec. 12 at 2:07 PM
$ANVS 2-3 yrs in Dagestan and we'll be fine xd
0 · Reply
Madsj79
Madsj79 Dec. 12 at 1:54 PM
0 · Reply
Madsj79
Madsj79 Dec. 12 at 1:49 PM
$ANVS https://cdn.prod.website-files.com/66b473381a97d1108ee4e2aa/693997f9b992da7907f5fad1_Annovis%20Corporate%20Presentation%20-%20December%202025%20.pdf
1 · Reply
wahoowa96
wahoowa96 Dec. 12 at 1:30 PM
$ANVS I thought 5 was intermediate highest to pause rise and do a back-test with a falling wedge style with around 33% drawdown. It went to 5 from 2 so 33% drawdown is about -1.3 from 5... theoretically settling around 3.6-3.7...Hoping to form a good support before heading to 8.
1 · Reply
ForestFoxes
ForestFoxes Dec. 12 at 6:03 AM
An $ANVS conversation ... @wormy01 I am moved by this thread that @Rbrmd started and sorry to hear that @justateacher is also dealing with this in her family's life. I would have moved mountains to help Dr. Maccecchini get the 200M to 250M she said she needed to run her pivotal trials based on believing that her drug was actually going to help patients. Once inside her company I started to see how she actually runs things, how little she thinks of patients in my opinion, and all of the contractual and SEC violations she is so comfortable in breaking. The lack of funding is not because of whatever nefarious story she is projecting or that Big Pharma is not ready to think out of the box to accept her drug's supposed mechanism of action. From what I have seen and from the 4 plus years that I have supported her in various ways I can absolutely state ... just read the many comments that I have posted on this channel over the previous months. Dr. Maccecchini is not what she purports to be. She can challenge me and all the observations I have, backed with the evidence, in a Courtroom over this. If anyone reading this has or does suffer huge financial losses in the future, please reach out to me. Unifying the lawsuits to come will have huge benefits. Nothing in my opinion based on what I have seen will benefit patients beyond the effect of a placebo. While that feels good for patients and their families for those who experience this while on buntanetap, NO pharmaceutical or biotechnology company focused in this space will partner, back, or provide financial support for Annovis Bio in my opinion based on drug efficacy. Although highly unlikely, if any support does occur it will be based on some other benefit, but NOT based on drug efficacy. Whatever efficacy there is, if there is any, is being wildly over stated by Dr. Maccecchini. She is welcome to speak for herself as she does read Stocktwits and has commented on this channel in the past. Dr. Maccecchini, you are welcome to join this conversation @MaccM
1 · Reply
dwayne09
dwayne09 Dec. 12 at 3:53 AM
$ANVS some people are bulls and some are bears, and that what make a market. I dont think Maria has intentionally mislead investors. She may have been overconfident due to her own conviction. Let it be and time will tell.
1 · Reply
MoneyGroupLLC
MoneyGroupLLC Dec. 12 at 3:37 AM
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0 · Reply
ForestFoxes
ForestFoxes Dec. 12 at 2:47 AM
It appears in one form or another that the CEO of $ANVS Dr. Maccecchini has convinced novice shareholders that the mysterious "dark side of Wall Street that the SEC ignores" is responsible for shareholders' suffering. (Image 1: Two posts from 5xStarTrader) Nothing could be farther from the truth. I know this because after being a loyal long-term investor and supporter since 2021 (like many of you), Dr. Maccecchini provided me her data to format in a way which would attract corporate support. It turns out that this is impossible IMO since she is a sloppy drug trial designer. I see some comments about Annovis Bio filing a cease and desist on today’s channel here. That would be an interesting dilemma. What things have I said about the company over the previous 100 post are untruth? Anything? (Image 4: C&D synopsis) But, first I want to understand why some investors think that the data is good? It is NOT which is one of the several reasons she doesn't have a true suitor. All the additional reasons are not good either. Is it because Dr. Maccecchini's repeated statement that she is “900% confident her drug works” sufficient for people ... despite the absence of hardly any robust evidence? Note: The evidence you think is robust ... isn't, IMO. It's only robust because Dr. Maccecchini tells you it is. No one else outside of her organization or anyone that isn't stuck with holding ANVS stock shares will agree with her. Why does Dr. Maccecchini feel that it is appropriate to attack authors who expose her bad data? (Image 2: DARVO 1) Why is there a need to blame entities who short her stock when it is her own poor work that Wall Street understands is very likely valueless? (Image 3: DARVO 2) Does she do so because she knows that novice investors will embrace this storyline and remain willingly blind to the truth about the efficacy, if any, of her drug? IMO, she is tugging at people’s heartstrings, their desire to help a loved one or invest in honor of one who has passed due to dementia, all while pitching the story of herself as the lone savior who will against all odds cure 20+ neurologic diseases!
2 · Reply