Jul. 31 at 1:58 AM
$AGEN @A_I_R_IKAZEE
Here's what I'm talking about Thin Air Head. Did you forget?
In 2024, Agenus (NASDAQ: AGEN) had three major pharmaceutical partners—**Bristol Myers Squibb (BMY)**, **Gilead Sciences**, and **Merck (MRK)**—return rights or allow option agreements to expire for partnered immuno-oncology programs.
Collectively, these terminations forfeited approximately **
$1.955 billion to
$2.015 billion** in potential future option fees, development, regulatory, and commercial milestone payments:
### Breakdown by Partner & Molecule
| Partner | Asset / Molecule | Target | Returned / Expired | Total Potential Milestones Returned |
| :--- | :--- | :--- | :--- | :--- |
| **Bristol Myers Squibb (BMY)** | **AGEN1777** | Anti-TIGIT / CD96 Bispecific | August 2024 | **~
$1.315 Billion –
$1.36 Billion** *(Up to
$1.36B total milestones, with ~
$45M realized prior to termination)* |