Market Cap 394.55M
Revenue (ttm) 2.85M
Net Income (ttm) -143.44M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -5,032.98%
Debt to Equity Ratio 0.00
Volume 688,200
Avg Vol 592,620
Day's Range N/A - N/A
Shares Out 54.42M
Stochastic %K 16%
Beta 1.10
Analysts Strong Sell
Price Target $43.33

Company Profile

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Industry: Biotechnology
Sector: Healthcare
Phone: 781 208 2466
Address:
890 Winter Street, Suite 200, Waltham, United States
notreload_ai
notreload_ai Jun. 3 at 2:51 PM
$DOCN $UPB $WPP -- THE WSJ
0 · Reply
Xrx12
Xrx12 Jun. 2 at 8:02 PM
$UPB buy tomorrow on another 15% haircut.
0 · Reply
Xrx12
Xrx12 Jun. 2 at 7:22 PM
$UPB no buying even at these prices. Looks like it's going far down
0 · Reply
Xrx12
Xrx12 Jun. 2 at 2:39 PM
$UPB going to 6s even
0 · Reply
Gunnar1
Gunnar1 May. 29 at 3:33 PM
$UPB Stepping back in here, starter for me.
0 · Reply
Xrx12
Xrx12 May. 28 at 8:46 PM
$UPB do we see 7s tomorrow?
0 · Reply
Xrx12
Xrx12 May. 19 at 7:57 PM
$UPB it's crazy how they can drag a phase 3 ready asset that is highly derisked to cash levels, but will be a buyer off this manipulation soon
0 · Reply
Trainguy1
Trainguy1 May. 15 at 3:26 PM
$UPB Upstream Bio will present new data on two posters from their Phase 2 VIBRANT trial of verekitug at the American Thoracic Society (ATS) 2026 International Conference in Orlando, Florida, on Monday, May 18, 2026, from 11:30 AM to 1:15 PM ET. The posters will be presented during the "B32 – Rise of the Biologics: A New Hope for Breathing Easier" session.
0 · Reply
Xrx12
Xrx12 May. 12 at 5:43 PM
$UPB should see $7S and lower soon 🙏. Will buy a lot then
0 · Reply
SuperGreenToday
SuperGreenToday May. 8 at 3:08 AM
$UPB Share Price: $8.99 Contract Selected: Nov 20, 2026 $10 Calls Buy Zone: $0.85 – $1.05 Target Zone: $1.45 – $1.77 Potential Upside: 61% ROI Time to Expiration: 196 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Latest News on UPB
Upstream Bio initiated with a Buy at H.C. Wainwright

2026-06-03T10:11:07.000Z - 1 day ago

Upstream Bio initiated with a Buy at H.C. Wainwright


Upstream Bio price target lowered to $50 from $51 at Mizuho

2026-05-14T12:37:47.000Z - 21 days ago

Upstream Bio price target lowered to $50 from $51 at Mizuho


Upstream Bio Earnings release: Q1 2026

May 13, 2026, 7:00 AM EDT - 22 days ago

Upstream Bio Earnings release: Q1 2026


Upstream Bio Quarterly report: Q1 2026

May 13, 2026, 7:00 AM EDT - 22 days ago

Upstream Bio Quarterly report: Q1 2026


Upstream Bio Slides: Corporate presentation

May 13, 2026, 7:00 AM EDT - 22 days ago

Upstream Bio Slides: Corporate presentation


Upstream Bio Proxy statement: Proxy filing

Apr 16, 2026, 8:00 AM EDT - 7 weeks ago

Upstream Bio Proxy statement: Proxy filing


Upstream Bio Proxy statement: Proxy filing

Apr 16, 2026, 8:00 AM EDT - 7 weeks ago

Upstream Bio Proxy statement: Proxy filing


Upstream Bio Slides: Corporate presentation

Apr 6, 2026, 7:00 AM EDT - 2 months ago

Upstream Bio Slides: Corporate presentation


Upstream Bio Annual report: Q4 2025

Mar 26, 2026, 7:00 AM EDT - 2 months ago

Upstream Bio Annual report: Q4 2025


Upstream Bio Earnings release: Q4 2025

Mar 26, 2026, 7:00 AM EDT - 2 months ago

Upstream Bio Earnings release: Q4 2025


Upstream Bio Slides: Corporate presentation

Mar 26, 2026, 7:00 AM EDT - 2 months ago

Upstream Bio Slides: Corporate presentation


Upstream Bio announces verekitug met the primary endpoint

2026-03-01T16:35:25.000Z - 3 months ago

Upstream Bio announces verekitug met the primary endpoint


Upstream Bio Transcript: Study result

Feb 11, 2026, 8:00 AM EST - 4 months ago

Upstream Bio Transcript: Study result


Upstream Bio Press release: Study result

Feb 11, 2026, 8:00 AM EST - 4 months ago

Upstream Bio Press release: Study result


Upstream Bio Slides: Study result

Feb 11, 2026, 8:00 AM EST - 4 months ago

Upstream Bio Slides: Study result


Upstream Bio management to meet virtually with Piper Sandler

2026-01-20T19:55:30.000Z - 4 months ago

Upstream Bio management to meet virtually with Piper Sandler


Upstream Bio Slides: Corporate presentation

Jan 9, 2026, 7:00 AM EST - 5 months ago

Upstream Bio Slides: Corporate presentation


Upstream Bio initiated with an Outperform at Mizuho

2025-12-17T21:16:04.000Z - 6 months ago

Upstream Bio initiated with an Outperform at Mizuho


Upstream Bio initiated with an Outperform at LifeSci Capital

2025-12-02T12:15:17.000Z - 6 months ago

Upstream Bio initiated with an Outperform at LifeSci Capital


Upstream Bio initiated with an Outperform at Evercore ISI

2025-11-18T09:55:15.000Z - 7 months ago

Upstream Bio initiated with an Outperform at Evercore ISI


Upstream Bio Transcript: Stifel 2025 Healthcare Conference

Nov 11, 2025, 9:20 AM EST - 7 months ago

Upstream Bio Transcript: Stifel 2025 Healthcare Conference


Upstream Bio Slides: Corporate Presentation

Nov 9, 2025, 6:00 PM EST - 7 months ago

Upstream Bio Slides: Corporate Presentation


Upstream Bio Quarterly report: Q3 2025

Nov 5, 2025, 7:00 AM EST - 7 months ago

Upstream Bio Quarterly report: Q3 2025


Upstream Bio Earnings release: Q3 2025

Nov 5, 2025, 7:00 AM EST - 7 months ago

Upstream Bio Earnings release: Q3 2025


Upstream Bio Transcript: Study Update

Sep 2, 2025, 8:00 AM EDT - 9 months ago

Upstream Bio Transcript: Study Update


Upstream Bio Press release: Study Update

Sep 2, 2025, 8:00 AM EDT - 9 months ago

Upstream Bio Press release: Study Update


Upstream Bio Slides: Study Update

Sep 2, 2025, 8:00 AM EDT - 9 months ago

Upstream Bio Slides: Study Update


Upstream Bio Earnings release: Q2 2025

Aug 6, 2025, 4:00 PM EDT - 10 months ago

Upstream Bio Earnings release: Q2 2025


Upstream Bio Quarterly report: Q2 2025

Aug 6, 2025, 4:00 PM EDT - 10 months ago

Upstream Bio Quarterly report: Q2 2025


Upstream Bio Appoints Stacy Price as Chief Technology Officer

May 20, 2025, 7:00 AM EDT - 1 year ago

Upstream Bio Appoints Stacy Price as Chief Technology Officer


Upstream Bio Quarterly report: Q1 2025

May 6, 2025, 7:00 AM EDT - 1 year ago

Upstream Bio Quarterly report: Q1 2025


Upstream Bio Earnings release: Q1 2025

May 6, 2025, 7:00 AM EDT - 1 year ago

Upstream Bio Earnings release: Q1 2025


Upstream Bio Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Upstream Bio Proxy statement: Proxy Filing


Upstream Bio Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Upstream Bio Proxy statement: Proxy Filing


Upstream Bio Earnings release: Q4 2024

Mar 12, 2025, 7:00 AM EDT - 1 year ago

Upstream Bio Earnings release: Q4 2024


Upstream Bio Annual report: Q4 2024

Mar 12, 2025, 7:00 AM EDT - 1 year ago

Upstream Bio Annual report: Q4 2024


Upstream Bio Announces Addition to Russell 2000® Index

Dec 16, 2024, 8:00 AM EST - 1 year ago

Upstream Bio Announces Addition to Russell 2000® Index


Upstream Bio Quarterly report: Q3 2024

Nov 7, 2024, 7:00 AM EST - 1 year ago

Upstream Bio Quarterly report: Q3 2024


Upstream Bio Earnings release: Q3 2024

Nov 7, 2024, 7:00 AM EST - 1 year ago

Upstream Bio Earnings release: Q3 2024


Upstream Bio valued at $1.1 bln as shares jump in Nasdaq debut

Oct 11, 2024, 12:49 PM EDT - 1 year ago

Upstream Bio valued at $1.1 bln as shares jump in Nasdaq debut


Upstream Bio raises $255 mln in US IPO

Oct 10, 2024, 7:42 PM EDT - 1 year ago

Upstream Bio raises $255 mln in US IPO


notreload_ai
notreload_ai Jun. 3 at 2:51 PM
$DOCN $UPB $WPP -- THE WSJ
0 · Reply
Xrx12
Xrx12 Jun. 2 at 8:02 PM
$UPB buy tomorrow on another 15% haircut.
0 · Reply
Xrx12
Xrx12 Jun. 2 at 7:22 PM
$UPB no buying even at these prices. Looks like it's going far down
0 · Reply
Xrx12
Xrx12 Jun. 2 at 2:39 PM
$UPB going to 6s even
0 · Reply
Gunnar1
Gunnar1 May. 29 at 3:33 PM
$UPB Stepping back in here, starter for me.
0 · Reply
Xrx12
Xrx12 May. 28 at 8:46 PM
$UPB do we see 7s tomorrow?
0 · Reply
Xrx12
Xrx12 May. 19 at 7:57 PM
$UPB it's crazy how they can drag a phase 3 ready asset that is highly derisked to cash levels, but will be a buyer off this manipulation soon
0 · Reply
Trainguy1
Trainguy1 May. 15 at 3:26 PM
$UPB Upstream Bio will present new data on two posters from their Phase 2 VIBRANT trial of verekitug at the American Thoracic Society (ATS) 2026 International Conference in Orlando, Florida, on Monday, May 18, 2026, from 11:30 AM to 1:15 PM ET. The posters will be presented during the "B32 – Rise of the Biologics: A New Hope for Breathing Easier" session.
0 · Reply
Xrx12
Xrx12 May. 12 at 5:43 PM
$UPB should see $7S and lower soon 🙏. Will buy a lot then
0 · Reply
SuperGreenToday
SuperGreenToday May. 8 at 3:08 AM
$UPB Share Price: $8.99 Contract Selected: Nov 20, 2026 $10 Calls Buy Zone: $0.85 – $1.05 Target Zone: $1.45 – $1.77 Potential Upside: 61% ROI Time to Expiration: 196 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Xrx12
Xrx12 May. 7 at 4:09 PM
$UPB keeping an eye as this looks like it'll drop off a cliff and give a great buying opportunity. Bearish for now
0 · Reply
Xrx12
Xrx12 May. 5 at 5:21 PM
$UPB Will revisit in low $8S or less
0 · Reply
Xrx12
Xrx12 May. 5 at 4:40 PM
$UPB I've sold - this stock is dead in the water, unfortunately. Seems like they're pulling from their $150M ATM and have no catalysts soon. Best of luck everyone!
0 · Reply
BillionerOfKing
BillionerOfKing Apr. 27 at 5:57 PM
$UPB Current Stock Price: $9.27 Contracts to trade: $10.0 UPB May 15 2026 Call Entry: $0.32 Exit: $0.60 ROI: 91% Hold ~23 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
Cheaslea76
Cheaslea76 Apr. 16 at 10:05 AM
$UPB earning 26th March
1 · Reply
bababooey143
bababooey143 Apr. 15 at 2:44 PM
$UPB I'm out no volume
0 · Reply
theBigDollarski
theBigDollarski Apr. 15 at 10:18 AM
0 · Reply
bababooey143
bababooey143 Apr. 11 at 9:39 PM
0 · Reply
bababooey143
bababooey143 Apr. 11 at 9:39 PM
$UPB it's says 10.80 on webull but 10.29 here?
0 · Reply
bababooey143
bababooey143 Apr. 9 at 9:40 PM
0 · Reply
theBigDollarski
theBigDollarski Apr. 9 at 7:24 PM
0 · Reply