Market Cap 190.96M
Revenue (ttm) 52.74M
Net Income (ttm) -6.60M
EPS (ttm) N/A
PE Ratio 12.61
Forward PE 11.64
Profit Margin -12.51%
Debt to Equity Ratio 0.00
Volume 389,970
Avg Vol 643,214
Day's Range N/A - N/A
Shares Out 80.57M
Stochastic %K 43%
Beta 0.00
Analysts Strong Sell
Price Target $11.00

Company Profile

Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company provides Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial fo...

Industry: Biotechnology
Sector: Healthcare
Phone: 201 696 9345
Address:
2 University Plaza, Suite 100, Hackensack, United States
PLX_BULLS
PLX_BULLS Aug. 4 at 1:39 PM
$PLX it appears that PLX sees combined sales of Elelyso at 23m with sales of Elfabrio at 35m and the milestone at 25m which totals 83m for 2026. Inasmuch, Q2 should be a better readout with Q3 being better yet. Let’s hope for positive surprise… like the FDA label expansion submission!
0 · Reply
nacho217
nacho217 Aug. 4 at 9:25 AM
$PLX The price is rejected again at 38, and that makes 15 times at this level.
1 · Reply
ElZocko2
ElZocko2 Aug. 4 at 7:49 AM
$PLX any reason why it should not drop on ER like usual?
1 · Reply
jcon777
jcon777 Aug. 4 at 4:10 AM
$PLX We could get an earnings announcement anytime or any day now. Note: the pic is AI generated just in case it looks too real. 😎
1 · Reply
CliffordCapital
CliffordCapital Aug. 3 at 5:08 PM
$PLX 2.45$ hard to break.. need a good ER for this…
0 · Reply
PLX_BULLS
PLX_BULLS Aug. 3 at 3:18 PM
$PLX Be nice to see a Monday Earnings release for next week.
1 · Reply
tpbachli
tpbachli Aug. 3 at 2:27 PM
$PLX volume this early is interesting
0 · Reply
PLX_BULLS
PLX_BULLS Aug. 3 at 2:10 PM
$PLX nice to see :). Run baby run!
1 · Reply
Artfldgr
Artfldgr Aug. 3 at 9:32 AM
$PLX anyone else notice this from last quarter??
1 · Reply
BambooPanda
BambooPanda Aug. 3 at 5:01 AM
$PLX Having a chat with Gemini on pharma product sales growth, Gemini states in interesting perspective on US high-value drug price changes over time vs the rest of the world. Gemini states outside the US (EU, Japan, Canada etc) where prices are agreed upon by governments the sales in CER terms go down over time. As governments do not allow price increases to offset inflation. Over longer periods of 5-10 years there are required price cuts. The only way to increase on CER is to find new patients or take away market share. This however is not the same for the US. As drug prices are based on free market pricing and the confidential PBM rebates. Thus in the USA, drugs like Fabrazyme regularly see an annual increase in WAC of 3-5%. If this is true then Fabrazyme should see US increases of 3-5% + the 7-8% CAGR = 10-13% CER growth. Given Fab US sales grew 5.5% CER, then patient share growth would be essentially flat. Meaning Elfabrio taking more USA patient share.
1 · Reply
Latest News on PLX
Protalix BioTherapeutics Earnings Call Transcript: Q1 2026

May 13, 2026, 8:00 AM EDT - 2 months ago

Protalix BioTherapeutics Earnings Call Transcript: Q1 2026


Protalix BioTherapeutics Earnings release: Q1 2026

May 13, 2026, 8:00 AM EDT - 2 months ago

Protalix BioTherapeutics Earnings release: Q1 2026


Protalix BioTherapeutics Quarterly report: Q1 2026

May 13, 2026, 8:00 AM EDT - 2 months ago

Protalix BioTherapeutics Quarterly report: Q1 2026


Protalix BioTherapeutics Slides: Corporate presentation

May 13, 2026, 7:00 AM EDT - 2 months ago

Protalix BioTherapeutics Slides: Corporate presentation


Protalix BioTherapeutics Proxy statement: Proxy filing

Apr 30, 2026, 8:00 AM EDT - 3 months ago

Protalix BioTherapeutics Proxy statement: Proxy filing


Protalix BioTherapeutics Earnings Call Transcript: Q4 2025

Mar 18, 2026, 8:00 AM EDT - 4 months ago

Protalix BioTherapeutics Earnings Call Transcript: Q4 2025


Protalix BioTherapeutics Annual report: Q4 2025

Mar 18, 2026, 8:00 AM EDT - 4 months ago

Protalix BioTherapeutics Annual report: Q4 2025


Protalix BioTherapeutics Earnings release: Q4 2025

Mar 18, 2026, 8:00 AM EDT - 4 months ago

Protalix BioTherapeutics Earnings release: Q4 2025


Protalix BioTherapeutics Letter to Stockholders

Jan 5, 2026, 6:50 AM EST - 7 months ago

Protalix BioTherapeutics Letter to Stockholders


Protalix BioTherapeutics Earnings Call Transcript: Q3 2025

Nov 13, 2025, 8:00 AM EST - 9 months ago

Protalix BioTherapeutics Earnings Call Transcript: Q3 2025


Protalix BioTherapeutics Quarterly report: Q3 2025

Nov 13, 2025, 8:00 AM EST - 9 months ago

Protalix BioTherapeutics Quarterly report: Q3 2025


Protalix BioTherapeutics Earnings release: Q3 2025

Nov 13, 2025, 8:00 AM EST - 9 months ago

Protalix BioTherapeutics Earnings release: Q3 2025


Protalix BioTherapeutics to Present at Investor Summit Virtual

Sep 11, 2025, 10:55 AM EDT - 11 months ago

Protalix BioTherapeutics to Present at Investor Summit Virtual


Protalix BioTherapeutics Earnings Call Transcript: Q2 2025

Aug 14, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings Call Transcript: Q2 2025


Protalix BioTherapeutics Quarterly report: Q2 2025

Aug 14, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Quarterly report: Q2 2025


Protalix BioTherapeutics Earnings release: Q2 2025

Aug 14, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings release: Q2 2025


Protalix appoints Gilad Mamlok as CFO

2025-07-21T10:55:33.000Z - 1 year ago

Protalix appoints Gilad Mamlok as CFO


Protalix added to Russell 3000, Russell 2000 Indexes

2025-06-30T14:45:15.000Z - 1 year ago

Protalix added to Russell 3000, Russell 2000 Indexes


Protalix BioTherapeutics Earnings Call Transcript: Q1 2025

May 9, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings Call Transcript: Q1 2025


Protalix BioTherapeutics Quarterly report: Q1 2025

May 9, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Quarterly report: Q1 2025


Protalix BioTherapeutics Earnings release: Q1 2025

May 9, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings release: Q1 2025


Protalix BioTherapeutics Proxy statement: Proxy Filing

Apr 30, 2025, 8:00 AM EDT - 1 year ago

Protalix BioTherapeutics Proxy statement: Proxy Filing


Protalix files $100M mixed securities shelf

2025-04-28T21:05:49.000Z - 1 year ago

Protalix files $100M mixed securities shelf


Protalix BioTherapeutics Earnings Call Transcript: Q4 2024

Mar 17, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings Call Transcript: Q4 2024


Protalix BioTherapeutics Annual report: Q4 2024

Mar 17, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Annual report: Q4 2024


Protalix BioTherapeutics Earnings release: Q4 2024

Mar 17, 2025, 8:30 AM EDT - 1 year ago

Protalix BioTherapeutics Earnings release: Q4 2024


Protalix BioTherapeutics Issues 2025 Letter to Stockholders

Dec 23, 2024, 6:50 AM EST - 1 year ago

Protalix BioTherapeutics Issues 2025 Letter to Stockholders


Protalix BioTherapeutics Earnings Call Transcript: Q3 2024

Nov 14, 2024, 8:30 AM EST - 1 year ago

Protalix BioTherapeutics Earnings Call Transcript: Q3 2024


Protalix BioTherapeutics Earnings release: Q3 2024

Nov 14, 2024, 8:30 AM EST - 1 year ago

Protalix BioTherapeutics Earnings release: Q3 2024


Protalix BioTherapeutics Quarterly report: Q3 2024

Nov 14, 2024, 8:30 AM EST - 1 year ago

Protalix BioTherapeutics Quarterly report: Q3 2024


Protalix BioTherapeutics Earnings Call Transcript: Q2 2024

Aug 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings Call Transcript: Q2 2024


Protalix BioTherapeutics Quarterly report: Q2 2024

Aug 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Quarterly report: Q2 2024


Protalix BioTherapeutics Earnings release: Q2 2024

Aug 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings release: Q2 2024


Protalix BioTherapeutics Transcript: Investor Day 2024

Jun 26, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Transcript: Investor Day 2024


Protalix BioTherapeutics Proxy statement: Proxy Filing

May 17, 2024, 8:00 AM EDT - 2 years ago

Protalix BioTherapeutics Proxy statement: Proxy Filing


Protalix BioTherapeutics Earnings Call Transcript: Q1 2024

May 10, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings Call Transcript: Q1 2024


Protalix BioTherapeutics Quarterly report: Q1 2024

May 10, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Quarterly report: Q1 2024


Protalix BioTherapeutics Earnings release: Q1 2024

May 10, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings release: Q1 2024


Protalix BioTherapeutics Proxy statement: Proxy Filing

Apr 29, 2024, 8:00 AM EDT - 2 years ago

Protalix BioTherapeutics Proxy statement: Proxy Filing


Protalix BioTherapeutics Earnings Call Transcript: Q4 2023

Mar 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings Call Transcript: Q4 2023


Protalix BioTherapeutics Annual report: Q4 2023

Mar 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Annual report: Q4 2023


Protalix BioTherapeutics Earnings release: Q4 2023

Mar 14, 2024, 8:30 AM EDT - 2 years ago

Protalix BioTherapeutics Earnings release: Q4 2023


Protalix BioTherapeutics Issues 2024 Letter to Stockholders

Dec 26, 2023, 6:50 AM EST - 2 years ago

Protalix BioTherapeutics Issues 2024 Letter to Stockholders


Protalix BioTherapeutics Earnings Call Transcript: Q3 2023

Nov 6, 2023, 8:30 AM EST - 2 years ago

Protalix BioTherapeutics Earnings Call Transcript: Q3 2023


Protalix BioTherapeutics Quarterly report: Q3 2023

Nov 6, 2023, 8:30 AM EST - 2 years ago

Protalix BioTherapeutics Quarterly report: Q3 2023


Protalix BioTherapeutics Earnings release: Q3 2023

Nov 6, 2023, 8:30 AM EST - 2 years ago

Protalix BioTherapeutics Earnings release: Q3 2023


PLX_BULLS
PLX_BULLS Aug. 4 at 1:39 PM
$PLX it appears that PLX sees combined sales of Elelyso at 23m with sales of Elfabrio at 35m and the milestone at 25m which totals 83m for 2026. Inasmuch, Q2 should be a better readout with Q3 being better yet. Let’s hope for positive surprise… like the FDA label expansion submission!
0 · Reply
nacho217
nacho217 Aug. 4 at 9:25 AM
$PLX The price is rejected again at 38, and that makes 15 times at this level.
1 · Reply
ElZocko2
ElZocko2 Aug. 4 at 7:49 AM
$PLX any reason why it should not drop on ER like usual?
1 · Reply
jcon777
jcon777 Aug. 4 at 4:10 AM
$PLX We could get an earnings announcement anytime or any day now. Note: the pic is AI generated just in case it looks too real. 😎
1 · Reply
CliffordCapital
CliffordCapital Aug. 3 at 5:08 PM
$PLX 2.45$ hard to break.. need a good ER for this…
0 · Reply
PLX_BULLS
PLX_BULLS Aug. 3 at 3:18 PM
$PLX Be nice to see a Monday Earnings release for next week.
1 · Reply
tpbachli
tpbachli Aug. 3 at 2:27 PM
$PLX volume this early is interesting
0 · Reply
PLX_BULLS
PLX_BULLS Aug. 3 at 2:10 PM
$PLX nice to see :). Run baby run!
1 · Reply
Artfldgr
Artfldgr Aug. 3 at 9:32 AM
$PLX anyone else notice this from last quarter??
1 · Reply
BambooPanda
BambooPanda Aug. 3 at 5:01 AM
$PLX Having a chat with Gemini on pharma product sales growth, Gemini states in interesting perspective on US high-value drug price changes over time vs the rest of the world. Gemini states outside the US (EU, Japan, Canada etc) where prices are agreed upon by governments the sales in CER terms go down over time. As governments do not allow price increases to offset inflation. Over longer periods of 5-10 years there are required price cuts. The only way to increase on CER is to find new patients or take away market share. This however is not the same for the US. As drug prices are based on free market pricing and the confidential PBM rebates. Thus in the USA, drugs like Fabrazyme regularly see an annual increase in WAC of 3-5%. If this is true then Fabrazyme should see US increases of 3-5% + the 7-8% CAGR = 10-13% CER growth. Given Fab US sales grew 5.5% CER, then patient share growth would be essentially flat. Meaning Elfabrio taking more USA patient share.
1 · Reply
CliffordCapital
CliffordCapital Aug. 2 at 8:19 PM
$PLX it‘s about time I make a profit here….5-6$ next year!
0 · Reply
MauriceMauriceMaurice
MauriceMauriceMaurice Aug. 2 at 1:42 PM
$PLX I am at the Missoni Room in the Byblos. Tugging my sack with close to 500 thousand shares in the bag
0 · Reply
brunoq14
brunoq14 Aug. 2 at 11:34 AM
$PLX BlackRock files 13G July 29 reporting ownership of 4.05M shares of Protalix, a 5.02% interest.
1 · Reply
PLX_BULLS
PLX_BULLS Aug. 2 at 3:37 AM
$PLX How could a Quebec Reimbursement Board not see the clear benefits of Elfabrio over Replagal? Here’s the eGGR slopes of the Replagal to Elfabrio crossover trial. Females went to perfect kidney function on Elfabrios! What’s even more concerning… I’m a construction worker. Crazy world! “No evidence”??
1 · Reply
Merlintrader
Merlintrader Aug. 1 at 7:16 PM
Protalix BioTherapeutics ($PLX) Elfabrio and Chiesi commercial execution, Elelyso cash generation, a milestone-heavy first quarter, a cleaner balance sheet, BlackRock above 5%, and PRX-115 as the medium-term gout catalyst. https://www.merlintrader.com/protalix-biotherapeutics-stock-hub/
1 · Reply
alexpitti
alexpitti Aug. 1 at 2:26 AM
$PLX i think they canceled or i forgot about it and didn't do it. whatever
6 · Reply
PLX_BULLS
PLX_BULLS Aug. 1 at 1:49 AM
$PLX Thanks to all the State School, Fire, Police, etc Pension Plans making a investment in PLX. Great to see! There’s so many Index/Mutual Funds buying too. Times are a changing. We just need a couple qtrs of good profit to rock and roll, and the FDA expansion submission will assist in fueling the train to the promise land :)
1 · Reply
Artfldgr
Artfldgr Jul. 31 at 11:39 PM
$PLX Results are in.. but I don't know if I will trade it.. if I have time the next check is trade forward on paper. Took three months to write it and work the data. 5 versions. Results only, no mechanism: Back tested on stocks and time periods held out from training, the system correctly predicted price direction 67–70% of the time, well above the 44–49% baseline rate for the underlying data. Performance held steady between training and validation, indicating the results are not an artifact of overfitting. When the system's own confidence measure was used to filter for its strongest calls, accuracy rose to the low-to-mid 90s%. The system performed comparably well in both directions. :)
0 · Reply
CliffordCapital
CliffordCapital Jul. 31 at 4:42 PM
$PLX this man is spitting pure gold. Unfortunately big insurances still prefer fabrazyme…. Need change for elfabrio uptake
0 · Reply
milt0n
milt0n Jul. 31 at 12:51 PM
$PLX Quebec apparently reached a different conclusion than the national reimbursement body in Canada with regards to reimbursement for Elfabrio. The Canada's Drug Agency (CDA-AMC) recommended that Elfabrio be reimbursed, provided it met the same eligibility criteria already used for other Fabry enzyme replacement therapies. However Quebec’s INESSS agency concluded that the available evidence was insufficient to demonstrate enough additional clinical benefit to justify listing the drug on the provincial formulary for reimbursement. https://www.ramq.gouv.qc.ca/fr/professionnels/medecin-omnipraticien-omnipraticienne/medicaments/valeur-therapeutique-non-reconnue CDA-AMC: "Cover it, but under conditions." Quebec (INESSS): "The evidence isn't strong enough to recognize therapeutic value, so don't list it." Sounds just like France where they denied reimbursement: “Why should the French healthcare system pay for this instead of the therapies it already has?”
6 · Reply
BambooPanda
BambooPanda Jul. 31 at 5:34 AM
$PLX So Sanofi USA is looking like the tougher nut to crack. But otherwise I would say positive! Fabrazyme: - Overall Fab sales flat at 0.4% CER, when the market should be growing at about 7-8% - Fab USA up +5.5% CER. - Fab EU flat at 0% CER, (not growing at 7-8%) - Fab ROW -9.1% CER with sales at 56M, on par with worst quarter in last 2+ years, this level only seen once Q3 2025 - (definitely not growing at 7-8%) Replagal: - EU sales at 10.1B AER = 9B CER. Representing a -7% drop in EU sales QoQ and -13% in EU sales YoY So given Fab sales are flat in EU, then someone is definitely taking up the slack and I don't think all of that is Galafold. (Again market growing at 7-8%) - ROW/GEM. Harder to compute CER due the number of currencies. But AER is 9.6B, which Gemini calculate approximately as 8.7B CER in that Region. Which indicates a -6.5% drop QoQ. Overall Replagal's worst quarter since tracking, despite benefitting from the FX tailwind.
1 · Reply
jcon777
jcon777 Jul. 31 at 3:32 AM
$PLX about two weeks til earnings. 😎
0 · Reply