Market Cap 140.74M
Revenue (ttm) 53.40M
Net Income (ttm) 2.93M
EPS (ttm) N/A
PE Ratio 25.57
Forward PE 71.60
Profit Margin 5.49%
Debt to Equity Ratio 0.00
Volume 402,300
Avg Vol 717,422
Day's Range N/A - N/A
Shares Out 80.42M
Stochastic %K 34%
Beta -0.25
Analysts Strong Sell
Price Target $11.00

Company Profile

Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company offers Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial for...

Industry: Biotechnology
Sector: Healthcare
Phone: 201 696 9345
Address:
2 University Plaza, Suite 100, Hackensack, United States
annushka
annushka Dec. 25 at 12:39 AM
$PLX Hello PLX warriors! Wishing you all a very Merry Christmas!🎄😍 Also, would like to remember our dear friend from haven Mike!!!
1 · Reply
Uktrader001
Uktrader001 Dec. 24 at 11:15 PM
$PLX Merry Christmas my fellow Plx hard core believers you know who you are.
1 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:49 PM
$PLX one of the figures in the images i just posted showed the difference between incidents with Elfabrio vs Fabrazyme directly comparing rather than the way they did produce this With Fabrazyme, you are 680% more likely to experience a reaction compared to Elfabrio.
1 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:44 PM
$PLX Google search AI
0 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:43 PM
$PLX from the EMA The benefits of Elfabrio were evaluated in one main study, involving 78 patients with Fabry disease. The study compared Elfabrio with Fabrazyme, another enzyme replacement therapy used to treat patients with Fabry disease. The main measure of effectiveness was based on glomerular filtration rate (GFR; a measure of how well the kidneys are working), which decreases as a patient’s kidney function gets worse. The average GFR reduced by 2.5 mL/min/1.73m2 per year after both 12 and 24 months of treatment with Elfabrio compared with 1.7 mL/min/1.73m2 and 2.2 mL/min/1.73m2 in those who received Fabrazyme. Supportive data showed a significant decrease in the levels of Gb3 in the kidneys and blood of patients treated with Elfabrio. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761161s000lbl.pdf
0 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:36 PM
$PLX https://www.ema.europa.eu/en/medicines/human/EPAR/elfabrio
0 · Reply
pmcd777
pmcd777 Dec. 24 at 3:12 PM
$PLX if there is one this year, should be soon. Probably a nonevent but still worth reading. Maybe.
2 · Reply
milt0n
milt0n Dec. 24 at 2:16 PM
$PLX Elfabrio popped up from a search today, on the Felleskatalogen which is the official Norwegian drug catalog. It may have been listed in the catalog for a longer period but : https://www.felleskatalogen.no/medisin/elfabrio-chiesi-farmaceutici-730928?direkte-oppslag=snomed&sokord=579321000202106 However, a medicine appearing in the catalog means it is authorized and marketed, but does not guarantee public funding. The latest available updates show Elfabrio is still under review in Norway’s Nye Metoder process. The next step is awaiting Beslutningsforum’s final ruling, which will determine whether Elfabrio is publicly funded for Fabry disease patients. The official agenda for Beslutningsforum meetings in 2025 is published on the Nye Metoder website. After looking at the past and upcoming meetings Elfabrio was not listed on any of the agendas. Hopefully we will see Elfabrio on an agenda in 2026. https://www.nyemetoder.no/moter-i-beslutningsforum-for-nye-metoder?utm_source=copilot.com
1 · Reply
brunoq14
brunoq14 Dec. 24 at 5:38 AM
$PLX Well, there's no reason to doubt that gout Phase 2 will be starting soon. First dose is scheduled for this quarter. No change has been announced by management, and that's what Zacks has printed.
0 · Reply
swarty
swarty Dec. 23 at 11:29 PM
$PLX I don't think I'm crazy but I cannot find when Elyal mentioned potentially renegotiating the rights with Pfizer or finding a new partner to go with Elelyso. Did I dream this or is the Internet being difficult with me today? Anyone that can confirm it happened or confirm I'm crazy in this?
4 · Reply
Latest News on PLX
Why Is Protalix BioTherapeutics Stock Falling On Friday?

Oct 17, 2025, 11:23 AM EDT - 2 months ago

Why Is Protalix BioTherapeutics Stock Falling On Friday?


Protalix BioTherapeutics to Present at Investor Summit Virtual

Sep 11, 2025, 10:55 AM EDT - 3 months ago

Protalix BioTherapeutics to Present at Investor Summit Virtual


Protalix BioTherapeutics Issues 2025 Letter to Stockholders

Dec 23, 2024, 6:50 AM EST - 1 year ago

Protalix BioTherapeutics Issues 2025 Letter to Stockholders


annushka
annushka Dec. 25 at 12:39 AM
$PLX Hello PLX warriors! Wishing you all a very Merry Christmas!🎄😍 Also, would like to remember our dear friend from haven Mike!!!
1 · Reply
Uktrader001
Uktrader001 Dec. 24 at 11:15 PM
$PLX Merry Christmas my fellow Plx hard core believers you know who you are.
1 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:49 PM
$PLX one of the figures in the images i just posted showed the difference between incidents with Elfabrio vs Fabrazyme directly comparing rather than the way they did produce this With Fabrazyme, you are 680% more likely to experience a reaction compared to Elfabrio.
1 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:44 PM
$PLX Google search AI
0 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:43 PM
$PLX from the EMA The benefits of Elfabrio were evaluated in one main study, involving 78 patients with Fabry disease. The study compared Elfabrio with Fabrazyme, another enzyme replacement therapy used to treat patients with Fabry disease. The main measure of effectiveness was based on glomerular filtration rate (GFR; a measure of how well the kidneys are working), which decreases as a patient’s kidney function gets worse. The average GFR reduced by 2.5 mL/min/1.73m2 per year after both 12 and 24 months of treatment with Elfabrio compared with 1.7 mL/min/1.73m2 and 2.2 mL/min/1.73m2 in those who received Fabrazyme. Supportive data showed a significant decrease in the levels of Gb3 in the kidneys and blood of patients treated with Elfabrio. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761161s000lbl.pdf
0 · Reply
Artfldgr
Artfldgr Dec. 24 at 3:36 PM
$PLX https://www.ema.europa.eu/en/medicines/human/EPAR/elfabrio
0 · Reply
pmcd777
pmcd777 Dec. 24 at 3:12 PM
$PLX if there is one this year, should be soon. Probably a nonevent but still worth reading. Maybe.
2 · Reply
milt0n
milt0n Dec. 24 at 2:16 PM
$PLX Elfabrio popped up from a search today, on the Felleskatalogen which is the official Norwegian drug catalog. It may have been listed in the catalog for a longer period but : https://www.felleskatalogen.no/medisin/elfabrio-chiesi-farmaceutici-730928?direkte-oppslag=snomed&sokord=579321000202106 However, a medicine appearing in the catalog means it is authorized and marketed, but does not guarantee public funding. The latest available updates show Elfabrio is still under review in Norway’s Nye Metoder process. The next step is awaiting Beslutningsforum’s final ruling, which will determine whether Elfabrio is publicly funded for Fabry disease patients. The official agenda for Beslutningsforum meetings in 2025 is published on the Nye Metoder website. After looking at the past and upcoming meetings Elfabrio was not listed on any of the agendas. Hopefully we will see Elfabrio on an agenda in 2026. https://www.nyemetoder.no/moter-i-beslutningsforum-for-nye-metoder?utm_source=copilot.com
1 · Reply
brunoq14
brunoq14 Dec. 24 at 5:38 AM
$PLX Well, there's no reason to doubt that gout Phase 2 will be starting soon. First dose is scheduled for this quarter. No change has been announced by management, and that's what Zacks has printed.
0 · Reply
swarty
swarty Dec. 23 at 11:29 PM
$PLX I don't think I'm crazy but I cannot find when Elyal mentioned potentially renegotiating the rights with Pfizer or finding a new partner to go with Elelyso. Did I dream this or is the Internet being difficult with me today? Anyone that can confirm it happened or confirm I'm crazy in this?
4 · Reply
BryGuy29
BryGuy29 Dec. 23 at 11:28 PM
$PLX today’s action was a perfect example of why I sold at least half of my position months ago. This stock is plagued and has very little hope of success. I don’t know why. But that’s what it looks like. Invest elsewhere, is my advice.
2 · Reply
JFais
JFais Dec. 23 at 9:14 PM
$PLX $IOVA $GERN- Appreciated David sharing a few of his options income trades to finish out the year Love it when ppl make my framework their own/ incorporate into their system & strategy
2 · Reply
CliffordCapital
CliffordCapital Dec. 23 at 9:08 PM
$PLX good volume last couple of days but no gain.
0 · Reply
brunoq14
brunoq14 Dec. 23 at 6:47 PM
$PLX Zacks current present value is $10. Difficult to determine target price until inventory for all regions has been consumed. Then demand can be judged. Not much earnings improvement from Elfabrio expected until 2027 (.69).
0 · Reply
milt0n
milt0n Dec. 23 at 5:30 PM
$PLX Interesting article detailing the recent Amicus acquisition by BioMarin. https://www.lqventures.com/lucid-diligence-brief-biomarin-to-acquire-amicus-therapeutics-for-4-8b/?utm_source=dlvr.it&utm_medium=threads&amp There are still some hurdles before the deal can be approved. They also have to get approvals from the EU Commission where Galafold generates significant revenue. Post-deal the article calls out the risk if BioMarin shifts resources away from Galafold marketing or integration falters, this could exacerbate volume stagnation. Galafold's growth could plateau if competing therapies continue to gain traction like Elfabrio and Fabrazyme, which target broader Fabry patient population. BioMarin is also taking on a huge debt load (~$3.7B) to fund the deal which is a pretty big strain on their balance sheet and it will be interesting to see if it limits R&D investments in Galafold expansions or force cost-cutting of Fabry-related resources. Will be interesting to follow Galafold’s sales after the acquisition to see how it plays out.
1 · Reply
ZacksSCR
ZacksSCR Dec. 23 at 3:21 PM
$PLX Secarna’s Antisense Oligonucleotide Discovery Collaboration https://buff.ly/XcVS2iH
1 · Reply
CEOBuysDisclosures
CEOBuysDisclosures Dec. 23 at 3:15 PM
$PLX CEO purchased 56,000 shares at $1.81 for a total of $101,360. Bashan Dror now owns 2,532,934 shares. https://ceo-buys.com
0 · Reply
Artfldgr
Artfldgr Dec. 23 at 2:42 PM
$PLX i just realized there may be a few retailers who have more shares than Dror Maybe Christian and the new CFO Mordred leaned on him
0 · Reply
Artfldgr
Artfldgr Dec. 23 at 2:39 PM
$PLX New filing!!
0 · Reply
Social_Idiot
Social_Idiot Dec. 23 at 2:37 PM
$PLX So, the place I put my money from the 40k tax loss shares that I sold here. I put in $SLS starting at $1.5. Dror, take note.
2 · Reply
CEOBuysDisclosures
CEOBuysDisclosures Dec. 23 at 2:30 PM
$PLX CEO purchased 56,000 shares at $1.81 for a total of $101,360. Bashan Dror now owns 2,532,934 shares. https://ceo-buys.com
1 · Reply
Llamalamb2921
Llamalamb2921 Dec. 23 at 2:25 PM
$PLX I think Dror may be signaling that even if the once per month dosing doesn’t get approved, the company is still in good shape.
1 · Reply