Market Cap 396.74M
Revenue (ttm) 0.00
Net Income (ttm) -55.14M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.09
Volume 80,400
Avg Vol 204,882
Day's Range N/A - N/A
Shares Out 51.19M
Stochastic %K 74%
Beta -0.27
Analysts Strong Sell
Price Target $21.30

Company Profile

enGene Holdings Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company that develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a non-viral monotherapy to treat non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) in patients that have been unresponsive to treatment with Bacillus Calmette-Guérin (BCG). enGene Holdings Inc. is based in Montreal, Canada.

Industry: Biotechnology
Sector: Healthcare
Phone: 514 332 4888
Address:
4868 Rue Levy, Suite 220, Montreal, Canada
Pipelinepivots
Pipelinepivots Oct. 3 at 4:07 PM
$SKYE $ENGN $BEEM $BLNE most microcaps dilute GIPR doesn’t need to. With cash flow, $100M+ in assets, and no heavy debt, this company is positioned to run clean. When rates drop, real estate names with strong books explode first. GIPR .... is undervalued, overlooked, and designed to go wild once volume sticks
0 · Reply
Stmkr
Stmkr Oct. 3 at 12:35 PM
$ENGN Very quiet board. Underfollowed by retail investors? Readout in Q4. Should be good based on what I see. 78% institutional ownership
0 · Reply
LudicrousReturns
LudicrousReturns Oct. 3 at 6:34 AM
02 OCT Ludicrous Returns Stock Model Update Stocks to buy now (for 10/3 market open): $BEEM, $ENGN, $SKYE
0 · Reply
Money_never_sleep
Money_never_sleep Oct. 1 at 3:49 AM
$ENGN $18 very
0 · Reply
CDCcsd
CDCcsd Sep. 16 at 1:26 PM
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 3:53 PM
Morgan Stanley has adjusted their stance on enGene Holdings ( $ENGN ), setting the rating to Overweight with a target price of 19 → 18.
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 10:30 AM
HC Wainwright & Co. updates rating for enGene Holdings ( $ENGN ) to Buy, target set at 25.
0 · Reply
David_M_
David_M_ Sep. 10 at 3:43 PM
I've done well with $ENGN, $COCH, and $VNTG which have, for some reason, never attracted the attention of retail.
0 · Reply
JarvisFlow
JarvisFlow Sep. 8 at 12:00 PM
HC Wainwright & Co. has updated their rating for enGene Holdings ( $ENGN ) to Buy with a price target of 25.
0 · Reply
ChessGM
ChessGM Sep. 3 at 2:03 AM
$ENGN "Heads up alert! Upcoming earnings on Tuesday, 9/9/2025 for $ENGN Neutral (5.3) ### Financial Analysis of enGene Holdings Inc. (Nasdaq: ENGN) enGene Holdings Inc., a clinical-stage company focused on non-viral gene therapy solutions, demonstrates a complex financial profile in its current development phase. The company's recent activities, such as participating in investor conferences and issuing inducement grants, highlight its strategic efforts to engage with investors and expand its workforce. However, as a clinical-stage company, enGene's financial metrics need to be evaluated with a forward-looking perspective. The Price-to-Earnings (P/E) ratio is not applicable, typical for companies in the early stages of commercialization. Instead, the focus remains on the company's potential for future earnings growth and market penetration. The company's Earnings Per Share (EPS) growth is anticipated to improve as clinical trials progress and potentially successful therapies reach commercialization. Although specific revenue forecasts are not publicly detailed, the company's strategic moves suggest a focus on expanding their therapeutic pipeline and aligning with industry trends. When compared to industry peers, enGene's approach to non-viral gene therapy is innovative, yet it faces intense competition from both viral-based gene therapy companies and other non-viral approaches. The company's valuation and strategic decisions will be significantly influenced by trial results and regulatory milestones. ### Upcoming Earnings Report enGene Holdings is poised for its upcoming earnings report, which is expected to shed light on its financial trajectory and operational progress. Historical performance has been characterized by the typical volatility associated with biotech firms in their clinical stages, with expenses largely driven by research and development. Analyst consensus estimates suggest cautious optimism, with expectations focusing on updates regarding clinical trials and strategic partnerships. The potential impact on the stock will heavily depend on any disclosed advancements in their therapeutic candidates and possible guidance on future developments. ### Sector Performance The biotechnology sector, particularly the gene therapy segment, has experienced varied performance recently. While innovation and breakthroughs continue to drive interest and investment, the sector faces challenges such as regulatory hurdles, high R&D costs, and fluctuating investor sentiment. The performance of this sector remains contingent upon technological advancements and successful clinical outcomes. enGene Holdings, operating within this dynamic environment, must navigate these factors while capitalizing on its unique non-viral approach to gene therapy. In summary, enGene Holdings Inc. stands at a critical juncture, with its future largely dependent on clinical success and strategic execution. Investors should monitor developments closely, considering the inherent volatility and potential upside within the gene therapy landscape. - Funds were net sellers of $ENGN during the previous reporting quarter. - Funds with large holdings in $ENGN include: - Adage Capital P, MV: $4MM. Fund Rank: 89% www.adagecapital.com - Last 10 days performance: 11% - Last 30 days performance: 25% - Last 90 days performance: 25% Some of the latest news articles: - Title: enGene to Participate in Upcoming Investor Conferences Publication Date: 8/27/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-participate-upcoming-investor-conferences-120000554.html?.tsrc=rss - Title: This enGene Holdings Insider Increased Their Holding In The Last Year Publication Date: 8/19/2025 12:20:59 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-holdings-insider-increased-holding-122059298.html?.tsrc=rss - Title: enGene Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4) Publication Date: 8/4/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-reports-inducement-grants-under-120000889.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
0 · Reply
Latest News on ENGN
enGene to Participate in Upcoming Investor Conferences

Aug 27, 2025, 8:00 AM EDT - 5 weeks ago

enGene to Participate in Upcoming Investor Conferences


enGene Announces the Resignation of its Chief Medical Officer

Jun 4, 2025, 8:30 AM EDT - 4 months ago

enGene Announces the Resignation of its Chief Medical Officer


enGene to Present at the Jefferies Global Healthcare Conference

May 29, 2025, 8:00 AM EDT - 4 months ago

enGene to Present at the Jefferies Global Healthcare Conference


enGene Names Amy Pott as Chief Global Commercialization Officer

May 28, 2025, 7:30 AM EDT - 4 months ago

enGene Names Amy Pott as Chief Global Commercialization Officer


enGene Holdings Inc.: Unknown Company Which Looks Like A Catch

Feb 27, 2025, 4:20 AM EST - 7 months ago

enGene Holdings Inc.: Unknown Company Which Looks Like A Catch


enGene Announces $60 Million Private Placement Financing

Oct 25, 2024, 8:00 AM EDT - 1 year ago

enGene Announces $60 Million Private Placement Financing


/C O R R E C T I O N -- enGene Inc./

Apr 9, 2024, 8:56 AM EDT - 1 year ago

/C O R R E C T I O N -- enGene Inc./


enGene Announces Leadership Succession Plan

Feb 14, 2024, 6:45 AM EST - 1 year ago

enGene Announces Leadership Succession Plan


enGene Appoints Ryan Daws as Chief Financial Officer

Nov 29, 2023, 7:00 AM EST - 2 years ago

enGene Appoints Ryan Daws as Chief Financial Officer


Pipelinepivots
Pipelinepivots Oct. 3 at 4:07 PM
$SKYE $ENGN $BEEM $BLNE most microcaps dilute GIPR doesn’t need to. With cash flow, $100M+ in assets, and no heavy debt, this company is positioned to run clean. When rates drop, real estate names with strong books explode first. GIPR .... is undervalued, overlooked, and designed to go wild once volume sticks
0 · Reply
Stmkr
Stmkr Oct. 3 at 12:35 PM
$ENGN Very quiet board. Underfollowed by retail investors? Readout in Q4. Should be good based on what I see. 78% institutional ownership
0 · Reply
LudicrousReturns
LudicrousReturns Oct. 3 at 6:34 AM
02 OCT Ludicrous Returns Stock Model Update Stocks to buy now (for 10/3 market open): $BEEM, $ENGN, $SKYE
0 · Reply
Money_never_sleep
Money_never_sleep Oct. 1 at 3:49 AM
$ENGN $18 very
0 · Reply
CDCcsd
CDCcsd Sep. 16 at 1:26 PM
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 3:53 PM
Morgan Stanley has adjusted their stance on enGene Holdings ( $ENGN ), setting the rating to Overweight with a target price of 19 → 18.
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 10:30 AM
HC Wainwright & Co. updates rating for enGene Holdings ( $ENGN ) to Buy, target set at 25.
0 · Reply
David_M_
David_M_ Sep. 10 at 3:43 PM
I've done well with $ENGN, $COCH, and $VNTG which have, for some reason, never attracted the attention of retail.
0 · Reply
JarvisFlow
JarvisFlow Sep. 8 at 12:00 PM
HC Wainwright & Co. has updated their rating for enGene Holdings ( $ENGN ) to Buy with a price target of 25.
0 · Reply
ChessGM
ChessGM Sep. 3 at 2:03 AM
$ENGN "Heads up alert! Upcoming earnings on Tuesday, 9/9/2025 for $ENGN Neutral (5.3) ### Financial Analysis of enGene Holdings Inc. (Nasdaq: ENGN) enGene Holdings Inc., a clinical-stage company focused on non-viral gene therapy solutions, demonstrates a complex financial profile in its current development phase. The company's recent activities, such as participating in investor conferences and issuing inducement grants, highlight its strategic efforts to engage with investors and expand its workforce. However, as a clinical-stage company, enGene's financial metrics need to be evaluated with a forward-looking perspective. The Price-to-Earnings (P/E) ratio is not applicable, typical for companies in the early stages of commercialization. Instead, the focus remains on the company's potential for future earnings growth and market penetration. The company's Earnings Per Share (EPS) growth is anticipated to improve as clinical trials progress and potentially successful therapies reach commercialization. Although specific revenue forecasts are not publicly detailed, the company's strategic moves suggest a focus on expanding their therapeutic pipeline and aligning with industry trends. When compared to industry peers, enGene's approach to non-viral gene therapy is innovative, yet it faces intense competition from both viral-based gene therapy companies and other non-viral approaches. The company's valuation and strategic decisions will be significantly influenced by trial results and regulatory milestones. ### Upcoming Earnings Report enGene Holdings is poised for its upcoming earnings report, which is expected to shed light on its financial trajectory and operational progress. Historical performance has been characterized by the typical volatility associated with biotech firms in their clinical stages, with expenses largely driven by research and development. Analyst consensus estimates suggest cautious optimism, with expectations focusing on updates regarding clinical trials and strategic partnerships. The potential impact on the stock will heavily depend on any disclosed advancements in their therapeutic candidates and possible guidance on future developments. ### Sector Performance The biotechnology sector, particularly the gene therapy segment, has experienced varied performance recently. While innovation and breakthroughs continue to drive interest and investment, the sector faces challenges such as regulatory hurdles, high R&D costs, and fluctuating investor sentiment. The performance of this sector remains contingent upon technological advancements and successful clinical outcomes. enGene Holdings, operating within this dynamic environment, must navigate these factors while capitalizing on its unique non-viral approach to gene therapy. In summary, enGene Holdings Inc. stands at a critical juncture, with its future largely dependent on clinical success and strategic execution. Investors should monitor developments closely, considering the inherent volatility and potential upside within the gene therapy landscape. - Funds were net sellers of $ENGN during the previous reporting quarter. - Funds with large holdings in $ENGN include: - Adage Capital P, MV: $4MM. Fund Rank: 89% www.adagecapital.com - Last 10 days performance: 11% - Last 30 days performance: 25% - Last 90 days performance: 25% Some of the latest news articles: - Title: enGene to Participate in Upcoming Investor Conferences Publication Date: 8/27/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-participate-upcoming-investor-conferences-120000554.html?.tsrc=rss - Title: This enGene Holdings Insider Increased Their Holding In The Last Year Publication Date: 8/19/2025 12:20:59 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-holdings-insider-increased-holding-122059298.html?.tsrc=rss - Title: enGene Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4) Publication Date: 8/4/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-reports-inducement-grants-under-120000889.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
0 · Reply
David_M_
David_M_ Aug. 29 at 12:37 PM
0 · Reply
stockanalysis_
stockanalysis_ Aug. 25 at 10:32 PM
After Hours Losers: $EPIX $ENGN $CAPS $WAI $MOLN https://stockanalysis.com/markets/afterhours/?ref=saveontrading
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BigSqueezeComing
BigSqueezeComing Aug. 19 at 10:21 PM
$ENGN hot ah movers
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RiskCPremium
RiskCPremium Aug. 4 at 7:44 PM
$RLMD Q2-2025 update of NDV-01 phase-2 trial data is very critical. If NDV-01 phase-2 trial data shows comparable level of efficacy as seen in the April 28 AUA presentation, and if there is any favorable feedback from FDA vis-a-vis phase-3 pivotal trial design, then the logical next step is that Dr. Raj Pruthi, current CMO will replace Traversa Sergio, Inturrisi and Manfredi's consiglierre. I believe Dr. Raj Pruthi's resignation from $ENGN and taking CMO job at $RLMD was conditional on that, he would be an excellent CEO and steward of $RLMD/NDV-01. Dr Pruthi will be able to promote co-operation with FDA, urologist community, regain the trust of investors and analysts, and secure funding to run the trial. So far NDV-01 looks to be the most efficacious combo for NMIBC chemo drug when compared against $URGN's recently approved ZUSDURI and J&J's tar-200 (July 17, 2025 received Priority Review status for already filed NDA). Trigone Pharma, please kick some butts, rescue you and $RLMD.
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Raxothus
Raxothus Aug. 1 at 5:31 PM
EOD FOLLOW-UP - 08/01/25 Tracking continuation watch from 07/31 based on today’s highs vs prior close ✅ $AVTX – Closed 7.89, hit 8.75 (+10.9%). Strong open pop, but failed to hold VWAP or push further. ✅ $FRGE – Closed 21.90, hit 23.37 (+6.7%). Strong breakout at open, clean continuation. ❌ $ATNM – Closed 1.66, hit 1.68 (+1.2%). Weak range, lacked momentum. ❌ $ENGN – Closed 3.77, hit 3.86 (+2.4%). Modest move, but reclaimed VWAP and showed decent structure. ❌ $CCRD – Closed 29.00, hit 28.17 (–2.9%). Gapped down and faded. No continuation. 📊 Recap Total: 5 Winners: 2 Faders: 3 Accuracy: 40% ⚠️ $FRGE gave a clean continuation. $AVTX technically hit +10%, but failed to hold structure or VWAP. $ATNM, $ENGN and $CCRD failed to deliver range or setup. #VWAP #Continuation #SmallCaps #DayTrading #EODSetups #Accountability
0 · Reply
Raxothus
Raxothus Jul. 31 at 7:30 PM
EOD CONTINUATION WATCHLIST – 07/31/25 Focused on stocks that held VWAP and pushed into Power Hour with strength. $AVTX – 19.07% move, 4.7x volume, 9.1% VWAP stretch. Micro float. Strong move and held well above VWAP into close. Needs open over 7.96+ for continuation $FRGE – 26.4% move, 3.0x volume, 6.9% VWAP stretch. Micro float. Explosive action with strong close. Watching for gap and clean open over 21.8+ to extend $ATNM – 7.01% move, 2.0x volume, 3.0% VWAP stretch. Small float. Grinded up steadily with VWAP support. Needs push over 1.74 to stay in play $ENGN – 5.71% move, 6.2x volume, -0.5% VWAP stretch. Small float. Volume was strong, but faded late. Needs VWAP reclaim over 3.80+ to reset momentum $CCRD – 10.55% move, 6.1x volume, -0.5% VWAP stretch. Micro float. Volume surged but no late power. Needs strong gap and reclaim over 29.76+ to watch Watching for gap and VWAP continuation only. Catalyst + volume = edge. No random holds. #EOD #VWAP #Momentum #SmallCaps #DayTrading #ContinuationSetups
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NVDAMillionaire
NVDAMillionaire Jul. 23 at 8:10 PM
$ENGN Brilliant piece that captures ENGN's situation perfectly. So if you want to update your understanding of ENGN or get to know ENGN better, this is essential reading. https://beyondspx.com/article/engene-holdings-unpacking-the-ddx-platform-and-path-to-bladder-cancer-market-engn
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Rage_Against_The_Machine
Rage_Against_The_Machine Jul. 8 at 12:14 PM
$ENGN reshuffles leadership ahead of pivotal commercialization phase. Board adds heavy hitters: Replimune co-founder Philip Astley-Sparke, Oncko's William Grossman, and Collegium founder Michael Heffernan. Internal promotions boost regulatory/clinical ops. Market watching closely as detalimogene's BCG-unresponsive bladder cancer candidate approaches finish line. https://www.sec.gov/Archives/edgar/data/1980845/000092963825002520/a8k.htm
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Stmkr
Stmkr Jun. 26 at 7:33 PM
$ENGN Have the "protocol refinements" been explained?
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Drugtrade
Drugtrade Jun. 25 at 7:31 PM
$ENGN like the technology, lots of cash low debt long starter here
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BigSqueezeComing
BigSqueezeComing Jun. 25 at 12:48 PM
0 · Reply
BigSqueezeComing
BigSqueezeComing Jun. 25 at 12:47 PM
$ENGN https://www.businesswire.com/news/home/20250625944717/en/FDA-Grants-RMAT-Designation-for-enGenes-Detalimogene-Enabling-Potential-for-Expedited-Review-in-High-Risk-Non-Muscle-Invasive-Bladder-Cancer
0 · Reply