Market Cap 309.70M
Revenue (ttm) 0.00
Net Income (ttm) -55.14M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.09
Volume 86,000
Avg Vol 138,822
Day's Range N/A - N/A
Shares Out 51.11M
Stochastic %K 64%
Beta -0.39
Analysts Strong Sell
Price Target $21.70

Company Profile

enGene Holdings Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company that develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a non-viral monotherapy to treat non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) in patients that have been unresponsive to treatment with Bacillus Calmette-Guérin (BCG). enGene Holdings Inc. is based in Montreal, Canada.

Industry: Biotechnology
Sector: Healthcare
Phone: 514 332 4888
Address:
4868 Rue Levy, Suite 220, Montreal, Canada
JarvisFlow
JarvisFlow Sep. 12 at 3:53 PM
Morgan Stanley has adjusted their stance on enGene Holdings ( $ENGN ), setting the rating to Overweight with a target price of 19 → 18.
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 10:30 AM
HC Wainwright & Co. updates rating for enGene Holdings ( $ENGN ) to Buy, target set at 25.
0 · Reply
David_M_
David_M_ Sep. 10 at 3:43 PM
I've done well with $ENGN, $COCH, and $VNTG which have, for some reason, never attracted the attention of retail.
0 · Reply
JarvisFlow
JarvisFlow Sep. 8 at 12:00 PM
HC Wainwright & Co. has updated their rating for enGene Holdings ( $ENGN ) to Buy with a price target of 25.
0 · Reply
ChessGM
ChessGM Sep. 3 at 2:03 AM
$ENGN "Heads up alert! Upcoming earnings on Tuesday, 9/9/2025 for $ENGN Neutral (5.3) ### Financial Analysis of enGene Holdings Inc. (Nasdaq: ENGN) enGene Holdings Inc., a clinical-stage company focused on non-viral gene therapy solutions, demonstrates a complex financial profile in its current development phase. The company's recent activities, such as participating in investor conferences and issuing inducement grants, highlight its strategic efforts to engage with investors and expand its workforce. However, as a clinical-stage company, enGene's financial metrics need to be evaluated with a forward-looking perspective. The Price-to-Earnings (P/E) ratio is not applicable, typical for companies in the early stages of commercialization. Instead, the focus remains on the company's potential for future earnings growth and market penetration. The company's Earnings Per Share (EPS) growth is anticipated to improve as clinical trials progress and potentially successful therapies reach commercialization. Although specific revenue forecasts are not publicly detailed, the company's strategic moves suggest a focus on expanding their therapeutic pipeline and aligning with industry trends. When compared to industry peers, enGene's approach to non-viral gene therapy is innovative, yet it faces intense competition from both viral-based gene therapy companies and other non-viral approaches. The company's valuation and strategic decisions will be significantly influenced by trial results and regulatory milestones. ### Upcoming Earnings Report enGene Holdings is poised for its upcoming earnings report, which is expected to shed light on its financial trajectory and operational progress. Historical performance has been characterized by the typical volatility associated with biotech firms in their clinical stages, with expenses largely driven by research and development. Analyst consensus estimates suggest cautious optimism, with expectations focusing on updates regarding clinical trials and strategic partnerships. The potential impact on the stock will heavily depend on any disclosed advancements in their therapeutic candidates and possible guidance on future developments. ### Sector Performance The biotechnology sector, particularly the gene therapy segment, has experienced varied performance recently. While innovation and breakthroughs continue to drive interest and investment, the sector faces challenges such as regulatory hurdles, high R&D costs, and fluctuating investor sentiment. The performance of this sector remains contingent upon technological advancements and successful clinical outcomes. enGene Holdings, operating within this dynamic environment, must navigate these factors while capitalizing on its unique non-viral approach to gene therapy. In summary, enGene Holdings Inc. stands at a critical juncture, with its future largely dependent on clinical success and strategic execution. Investors should monitor developments closely, considering the inherent volatility and potential upside within the gene therapy landscape. - Funds were net sellers of $ENGN during the previous reporting quarter. - Funds with large holdings in $ENGN include: - Adage Capital P, MV: $4MM. Fund Rank: 89% www.adagecapital.com - Last 10 days performance: 11% - Last 30 days performance: 25% - Last 90 days performance: 25% Some of the latest news articles: - Title: enGene to Participate in Upcoming Investor Conferences Publication Date: 8/27/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-participate-upcoming-investor-conferences-120000554.html?.tsrc=rss - Title: This enGene Holdings Insider Increased Their Holding In The Last Year Publication Date: 8/19/2025 12:20:59 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-holdings-insider-increased-holding-122059298.html?.tsrc=rss - Title: enGene Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4) Publication Date: 8/4/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-reports-inducement-grants-under-120000889.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
0 · Reply
David_M_
David_M_ Aug. 29 at 12:37 PM
0 · Reply
stockanalysis_
stockanalysis_ Aug. 25 at 10:32 PM
After Hours Losers: $EPIX $ENGN $CAPS $WAI $MOLN https://stockanalysis.com/markets/afterhours/?ref=saveontrading
0 · Reply
BigSqueezeComing
BigSqueezeComing Aug. 19 at 10:21 PM
$ENGN hot ah movers
0 · Reply
RiskCPremium
RiskCPremium Aug. 4 at 7:44 PM
$RLMD Q2-2025 update of NDV-01 phase-2 trial data is very critical. If NDV-01 phase-2 trial data shows comparable level of efficacy as seen in the April 28 AUA presentation, and if there is any favorable feedback from FDA vis-a-vis phase-3 pivotal trial design, then the logical next step is that Dr. Raj Pruthi, current CMO will replace Traversa Sergio, Inturrisi and Manfredi's consiglierre. I believe Dr. Raj Pruthi's resignation from $ENGN and taking CMO job at $RLMD was conditional on that, he would be an excellent CEO and steward of $RLMD/NDV-01. Dr Pruthi will be able to promote co-operation with FDA, urologist community, regain the trust of investors and analysts, and secure funding to run the trial. So far NDV-01 looks to be the most efficacious combo for NMIBC chemo drug when compared against $URGN's recently approved ZUSDURI and J&J's tar-200 (July 17, 2025 received Priority Review status for already filed NDA). Trigone Pharma, please kick some butts, rescue you and $RLMD.
0 · Reply
Raxothus
Raxothus Aug. 1 at 5:31 PM
EOD FOLLOW-UP - 08/01/25 Tracking continuation watch from 07/31 based on today’s highs vs prior close ✅ $AVTX – Closed 7.89, hit 8.75 (+10.9%). Strong open pop, but failed to hold VWAP or push further. ✅ $FRGE – Closed 21.90, hit 23.37 (+6.7%). Strong breakout at open, clean continuation. ❌ $ATNM – Closed 1.66, hit 1.68 (+1.2%). Weak range, lacked momentum. ❌ $ENGN – Closed 3.77, hit 3.86 (+2.4%). Modest move, but reclaimed VWAP and showed decent structure. ❌ $CCRD – Closed 29.00, hit 28.17 (–2.9%). Gapped down and faded. No continuation. 📊 Recap Total: 5 Winners: 2 Faders: 3 Accuracy: 40% ⚠️ $FRGE gave a clean continuation. $AVTX technically hit +10%, but failed to hold structure or VWAP. $ATNM, $ENGN and $CCRD failed to deliver range or setup. #VWAP #Continuation #SmallCaps #DayTrading #EODSetups #Accountability
0 · Reply
Latest News on ENGN
enGene to Participate in Upcoming Investor Conferences

Aug 27, 2025, 8:00 AM EDT - 16 days ago

enGene to Participate in Upcoming Investor Conferences


enGene Announces the Resignation of its Chief Medical Officer

Jun 4, 2025, 8:30 AM EDT - 3 months ago

enGene Announces the Resignation of its Chief Medical Officer


enGene to Present at the Jefferies Global Healthcare Conference

May 29, 2025, 8:00 AM EDT - 3 months ago

enGene to Present at the Jefferies Global Healthcare Conference


enGene Names Amy Pott as Chief Global Commercialization Officer

May 28, 2025, 7:30 AM EDT - 3 months ago

enGene Names Amy Pott as Chief Global Commercialization Officer


enGene Holdings Inc.: Unknown Company Which Looks Like A Catch

Feb 27, 2025, 4:20 AM EST - 7 months ago

enGene Holdings Inc.: Unknown Company Which Looks Like A Catch


enGene Announces $60 Million Private Placement Financing

Oct 25, 2024, 8:00 AM EDT - 11 months ago

enGene Announces $60 Million Private Placement Financing


/C O R R E C T I O N -- enGene Inc./

Apr 9, 2024, 8:56 AM EDT - 1 year ago

/C O R R E C T I O N -- enGene Inc./


enGene Announces Leadership Succession Plan

Feb 14, 2024, 6:45 AM EST - 1 year ago

enGene Announces Leadership Succession Plan


enGene Appoints Ryan Daws as Chief Financial Officer

Nov 29, 2023, 7:00 AM EST - 1 year ago

enGene Appoints Ryan Daws as Chief Financial Officer


JarvisFlow
JarvisFlow Sep. 12 at 3:53 PM
Morgan Stanley has adjusted their stance on enGene Holdings ( $ENGN ), setting the rating to Overweight with a target price of 19 → 18.
0 · Reply
JarvisFlow
JarvisFlow Sep. 12 at 10:30 AM
HC Wainwright & Co. updates rating for enGene Holdings ( $ENGN ) to Buy, target set at 25.
0 · Reply
David_M_
David_M_ Sep. 10 at 3:43 PM
I've done well with $ENGN, $COCH, and $VNTG which have, for some reason, never attracted the attention of retail.
0 · Reply
JarvisFlow
JarvisFlow Sep. 8 at 12:00 PM
HC Wainwright & Co. has updated their rating for enGene Holdings ( $ENGN ) to Buy with a price target of 25.
0 · Reply
ChessGM
ChessGM Sep. 3 at 2:03 AM
$ENGN "Heads up alert! Upcoming earnings on Tuesday, 9/9/2025 for $ENGN Neutral (5.3) ### Financial Analysis of enGene Holdings Inc. (Nasdaq: ENGN) enGene Holdings Inc., a clinical-stage company focused on non-viral gene therapy solutions, demonstrates a complex financial profile in its current development phase. The company's recent activities, such as participating in investor conferences and issuing inducement grants, highlight its strategic efforts to engage with investors and expand its workforce. However, as a clinical-stage company, enGene's financial metrics need to be evaluated with a forward-looking perspective. The Price-to-Earnings (P/E) ratio is not applicable, typical for companies in the early stages of commercialization. Instead, the focus remains on the company's potential for future earnings growth and market penetration. The company's Earnings Per Share (EPS) growth is anticipated to improve as clinical trials progress and potentially successful therapies reach commercialization. Although specific revenue forecasts are not publicly detailed, the company's strategic moves suggest a focus on expanding their therapeutic pipeline and aligning with industry trends. When compared to industry peers, enGene's approach to non-viral gene therapy is innovative, yet it faces intense competition from both viral-based gene therapy companies and other non-viral approaches. The company's valuation and strategic decisions will be significantly influenced by trial results and regulatory milestones. ### Upcoming Earnings Report enGene Holdings is poised for its upcoming earnings report, which is expected to shed light on its financial trajectory and operational progress. Historical performance has been characterized by the typical volatility associated with biotech firms in their clinical stages, with expenses largely driven by research and development. Analyst consensus estimates suggest cautious optimism, with expectations focusing on updates regarding clinical trials and strategic partnerships. The potential impact on the stock will heavily depend on any disclosed advancements in their therapeutic candidates and possible guidance on future developments. ### Sector Performance The biotechnology sector, particularly the gene therapy segment, has experienced varied performance recently. While innovation and breakthroughs continue to drive interest and investment, the sector faces challenges such as regulatory hurdles, high R&D costs, and fluctuating investor sentiment. The performance of this sector remains contingent upon technological advancements and successful clinical outcomes. enGene Holdings, operating within this dynamic environment, must navigate these factors while capitalizing on its unique non-viral approach to gene therapy. In summary, enGene Holdings Inc. stands at a critical juncture, with its future largely dependent on clinical success and strategic execution. Investors should monitor developments closely, considering the inherent volatility and potential upside within the gene therapy landscape. - Funds were net sellers of $ENGN during the previous reporting quarter. - Funds with large holdings in $ENGN include: - Adage Capital P, MV: $4MM. Fund Rank: 89% www.adagecapital.com - Last 10 days performance: 11% - Last 30 days performance: 25% - Last 90 days performance: 25% Some of the latest news articles: - Title: enGene to Participate in Upcoming Investor Conferences Publication Date: 8/27/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-participate-upcoming-investor-conferences-120000554.html?.tsrc=rss - Title: This enGene Holdings Insider Increased Their Holding In The Last Year Publication Date: 8/19/2025 12:20:59 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-holdings-insider-increased-holding-122059298.html?.tsrc=rss - Title: enGene Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4) Publication Date: 8/4/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-reports-inducement-grants-under-120000889.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
0 · Reply
David_M_
David_M_ Aug. 29 at 12:37 PM
0 · Reply
stockanalysis_
stockanalysis_ Aug. 25 at 10:32 PM
After Hours Losers: $EPIX $ENGN $CAPS $WAI $MOLN https://stockanalysis.com/markets/afterhours/?ref=saveontrading
0 · Reply
BigSqueezeComing
BigSqueezeComing Aug. 19 at 10:21 PM
$ENGN hot ah movers
0 · Reply
RiskCPremium
RiskCPremium Aug. 4 at 7:44 PM
$RLMD Q2-2025 update of NDV-01 phase-2 trial data is very critical. If NDV-01 phase-2 trial data shows comparable level of efficacy as seen in the April 28 AUA presentation, and if there is any favorable feedback from FDA vis-a-vis phase-3 pivotal trial design, then the logical next step is that Dr. Raj Pruthi, current CMO will replace Traversa Sergio, Inturrisi and Manfredi's consiglierre. I believe Dr. Raj Pruthi's resignation from $ENGN and taking CMO job at $RLMD was conditional on that, he would be an excellent CEO and steward of $RLMD/NDV-01. Dr Pruthi will be able to promote co-operation with FDA, urologist community, regain the trust of investors and analysts, and secure funding to run the trial. So far NDV-01 looks to be the most efficacious combo for NMIBC chemo drug when compared against $URGN's recently approved ZUSDURI and J&J's tar-200 (July 17, 2025 received Priority Review status for already filed NDA). Trigone Pharma, please kick some butts, rescue you and $RLMD.
0 · Reply
Raxothus
Raxothus Aug. 1 at 5:31 PM
EOD FOLLOW-UP - 08/01/25 Tracking continuation watch from 07/31 based on today’s highs vs prior close ✅ $AVTX – Closed 7.89, hit 8.75 (+10.9%). Strong open pop, but failed to hold VWAP or push further. ✅ $FRGE – Closed 21.90, hit 23.37 (+6.7%). Strong breakout at open, clean continuation. ❌ $ATNM – Closed 1.66, hit 1.68 (+1.2%). Weak range, lacked momentum. ❌ $ENGN – Closed 3.77, hit 3.86 (+2.4%). Modest move, but reclaimed VWAP and showed decent structure. ❌ $CCRD – Closed 29.00, hit 28.17 (–2.9%). Gapped down and faded. No continuation. 📊 Recap Total: 5 Winners: 2 Faders: 3 Accuracy: 40% ⚠️ $FRGE gave a clean continuation. $AVTX technically hit +10%, but failed to hold structure or VWAP. $ATNM, $ENGN and $CCRD failed to deliver range or setup. #VWAP #Continuation #SmallCaps #DayTrading #EODSetups #Accountability
0 · Reply
Raxothus
Raxothus Jul. 31 at 7:30 PM
EOD CONTINUATION WATCHLIST – 07/31/25 Focused on stocks that held VWAP and pushed into Power Hour with strength. $AVTX – 19.07% move, 4.7x volume, 9.1% VWAP stretch. Micro float. Strong move and held well above VWAP into close. Needs open over 7.96+ for continuation $FRGE – 26.4% move, 3.0x volume, 6.9% VWAP stretch. Micro float. Explosive action with strong close. Watching for gap and clean open over 21.8+ to extend $ATNM – 7.01% move, 2.0x volume, 3.0% VWAP stretch. Small float. Grinded up steadily with VWAP support. Needs push over 1.74 to stay in play $ENGN – 5.71% move, 6.2x volume, -0.5% VWAP stretch. Small float. Volume was strong, but faded late. Needs VWAP reclaim over 3.80+ to reset momentum $CCRD – 10.55% move, 6.1x volume, -0.5% VWAP stretch. Micro float. Volume surged but no late power. Needs strong gap and reclaim over 29.76+ to watch Watching for gap and VWAP continuation only. Catalyst + volume = edge. No random holds. #EOD #VWAP #Momentum #SmallCaps #DayTrading #ContinuationSetups
0 · Reply
NVDAMillionaire
NVDAMillionaire Jul. 23 at 8:10 PM
$ENGN Brilliant piece that captures ENGN's situation perfectly. So if you want to update your understanding of ENGN or get to know ENGN better, this is essential reading. https://beyondspx.com/article/engene-holdings-unpacking-the-ddx-platform-and-path-to-bladder-cancer-market-engn
0 · Reply
Rage_Against_The_Machine
Rage_Against_The_Machine Jul. 8 at 12:14 PM
$ENGN reshuffles leadership ahead of pivotal commercialization phase. Board adds heavy hitters: Replimune co-founder Philip Astley-Sparke, Oncko's William Grossman, and Collegium founder Michael Heffernan. Internal promotions boost regulatory/clinical ops. Market watching closely as detalimogene's BCG-unresponsive bladder cancer candidate approaches finish line. https://www.sec.gov/Archives/edgar/data/1980845/000092963825002520/a8k.htm
0 · Reply
Stmkr
Stmkr Jun. 26 at 7:33 PM
$ENGN Have the "protocol refinements" been explained?
0 · Reply
Drugtrade
Drugtrade Jun. 25 at 7:31 PM
$ENGN like the technology, lots of cash low debt long starter here
0 · Reply
BigSqueezeComing
BigSqueezeComing Jun. 25 at 12:48 PM
0 · Reply
BigSqueezeComing
BigSqueezeComing Jun. 25 at 12:47 PM
$ENGN https://www.businesswire.com/news/home/20250625944717/en/FDA-Grants-RMAT-Designation-for-enGenes-Detalimogene-Enabling-Potential-for-Expedited-Review-in-High-Risk-Non-Muscle-Invasive-Bladder-Cancer
0 · Reply
DonCorleone77
DonCorleone77 Jun. 25 at 12:04 PM
$ENGN enGene gets Regenerative Medicine Advanced Therapy designation for detalimogene enGene announced that the FDA has granted Regenerative Medicine Advanced Therapy designation to detalimogene voraplasmid, the company's investigational therapy for the treatment of high-risk, Bacillus Calmette-Guerin-unresponsive, non-muscle invasive bladder cancer with carcinoma in situ.
0 · Reply
ChessGM
ChessGM Jun. 6 at 3:23 PM
Heads up alert! upcoming earnings on 6/10/2025 for $ENGN Neutral (5.5) enGene Holdings Inc.operates within the clinical-stage, non-viral genetic medicines sector, which has been characterized by evolving technologies and increasing investments. The resignation of the Chief Medical Officer, Dr. Raj Pruthi, may raise concerns regarding leadership stability, particularly as enGene is navigating complex clinical trials and commercialization strategies. However, the appointment of Amy Pott as Chief Global Commercialization Officer indicates a commitment to strengthening its commercial strategy, which could bode well for future revenue generation. From a financial perspective, enGene's P/E ratio remains undetermined due to its clinical-stage status and negative earnings. The company is expected to achieve significant EPS growth as it moves towards commercialization; however, concrete forecasts are yet to be established. Revenue growth prospects hinge on successful trial outcomes and regulatory approvals which currently remain speculative. Comparatively, enGene's performance metrics will need to be benchmarked against industry peers, such as Moderna and CRISPR Therapeutics, which have more established product pipelines and revenue streams. The sector overall has seen mixed performance recently, with advancements in genetic therapies driven by heightened investor interest and regulatory support. However, ongoing challenges, including market competition and the timeline for product approvals, continue to create volatility in stock valuations. --- In terms of upcoming earnings reports, expectations for enGene are cautiously optimistic. Analysts are closely monitoring developments tied to clinical trials and regulatory submissions, which could impact future revenue forecasts. Historical performance shows that the company has yet to report earnings that meet investor expectations, given its developmental stage. Analyst consensus estimates suggest a focus on the anticipated milestones in product development rather than traditional earnings metrics at this juncture. The impact on stock performance could be significant if enGene reports favorable outcomes or strategic partnerships that enhance its market position. Overall, the sector to which enGene belongs has been dynamic, with strong tailwinds from technological advancements in genetic medicine, but also faces the inherent risks associated with clinical development and market adoption. - Funds were net buyers of $ENGN during the previous reporting quarter. - Top 4 funds with large holdings in $ENGN: - Kynam Capital M, MV: $22MM. Fund Rank: 81% - Adage Capital P, MV: $7MM. Fund Rank: 79% www.adagecapital.com - Point72 Asset Management LP, MV: $6MM. Fund Rank: 91% www.point72.com - OrbiMed Advisors LLC, MV: $4MM. Fund Rank: 63% www.orbimed.com - Last 10 days performance: -10% - Last 30 days performance: -1% - Last 90 days performance: -31% Some of the latest news articles: - Title: enGene Announces the Resignation of its Chief Medical Officer Publication Date: 6/4/2025 12:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-announces-resignation-chief-medical-123000067.html?.tsrc=rss - Title: enGene to Present at the Jefferies Global Healthcare Conference Publication Date: 5/29/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/engene-present-jefferies-global-healthcare-120000205.html?.tsrc=rss - Title: enGene Names Amy Pott as Chief Global Commercialization Officer Publication Date: 5/28/2025 11:30:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/engene-names-amy-pott-chief-113000629.html?.tsrc=rss - Title: enGene to Participate in Upcoming Investor Conferences Publication Date: 4/29/2025 11:30:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/engene-participate-upcoming-investor-conferences-120000360.html?.tsrc=rss Follow ChessGM on stocktwits.com to get timely earnings alerts. Not a financial advice. Not a trading signal.
0 · Reply
David_M_
David_M_ May. 30 at 3:11 AM
$ENGN Only 919 watching?
1 · Reply
BioTuesdays
BioTuesdays May. 28 at 2:53 PM
enGene announced the appointment of Amy Pott as chief global commercialization officer—the company’s first dedicated executive for commercialization endeavors—reporting to Ron Cooper, CEO of enGene $ENGN https://biotuesdays.com/2025/05/28/engene-appoints-amy-pott-at-chief-global-commercialization-officer/
0 · Reply
asa123
asa123 May. 15 at 6:07 PM
$ENGN 430K volume out of nowhere, no news, up 12% - this is float ignition, not hype. Let's see if it holds above 3. I said yesterday the float was mispriced. Today someone agreed.
2 · Reply