Market Cap 44.38M
Revenue (ttm) 340,000.00
Net Income (ttm) -39.40M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -11,588.24%
Debt to Equity Ratio -0.37
Volume 93,200
Avg Vol 190,358
Day's Range N/A - N/A
Shares Out 10.85M
Stochastic %K 22%
Beta 0.87
Analysts Strong Sell
Price Target $31.86

Company Profile

Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug candidate is CNM-Au8, which is being studied in various clinical trials, including a completed Phase 2 platform trial to evaluate the safety and efficacy of CNM-Au8 in patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; comp...

Industry: Packaged Foods
Sector: Consumer Defensive
Phone: 801 676 9695
Website: clene.com
Address:
6550 South Millrock Drive, Suite G50, Salt Lake City, United States
Chris150
Chris150 Feb. 3 at 9:12 PM
$CLNN According to a newly published Form 144 SEC Filing, Chidozie will sell another 60.842 shares. Feel free to make any corrections if you like. https://www.sec.gov/Archives/edgar/data/1822791/000162828026004957/xsl144X01/primary_doc.xml
1 · Reply
Mulhollandr
Mulhollandr Feb. 3 at 6:41 PM
$CLNN just reminding everyone. Rob says February on this call. FDA type C happens any day now.
0 · Reply
Ravery
Ravery Feb. 3 at 1:27 PM
$CLNN At this point Chidozie is just a constant drag on the stock. If he is looking to unload a large chunk of shares why not reach out to a small fund or another large investor and work out a block trade? Maybe he was unable to do so, or maybe the company pissed him off and this is a form of retaliation. Investors sell for lots of reasons, but how they sell matters. Consistently dumping smaller blocks on an illiquid stock regardless of price is a bad look. The Matlin buy on 1/13 was positive, but that is being swamped by all the sell orders. The market hates uncertainty and today's stock price reflects that.
1 · Reply
Mulhollandr
Mulhollandr Feb. 3 at 12:16 AM
$CLNN still a bit of a mystery here bc chidozie sold more than the form 144 allows. I’m frankly at a loss. Unless the sales on 12/3 and 12/4 don’t count as part of the form 144. If that’s the case then he still has 100k shares to sell. Honestly I do not know. Anyone have any thoughts?
1 · Reply
7m3835d3
7m3835d3 Feb. 2 at 11:20 PM
$CLNN here we go, this explains it, and now it’s time to go up https://invest.clene.com/static-files/b085192e-0b00-43a1-8616-4ffab367a349
0 · Reply
neuroinvestor3
neuroinvestor3 Feb. 2 at 4:24 PM
$CLNN reposting this to improve morale - “This study showed not only paraclinical evidence of remyelination and improved axonal function, but measurable improvements in previously fixed deficits that we really haven’t seen any therapy in MS do,” said Michael Barnett, MBBS, PhD. Dr. Barnett is lead author of VISIONARY-MS Long-Term Extension: A Multi-Centre, Open-Label Long-Term Extension Study of CNM-Au8 in Patients with Stable Relapsing Multiple Sclerosis. “We saw an improvement and this was, for me, very unexpected,” said Dr. Barnett, professor of neurology at the Brain and Mind Centre, the University of Sydney, and Royal Prince Alfred Hospital, Sydney. “This therapy does not regenerate nerves or axons, but I suspect what it is doing is improving axonal function and therefore allowing electrical conduction through those nerve fibers that contribute to the greater amplitude of the response.” https://www.medcentral.com/neurology/ms/multiple-sclerosis-study-shows-cnm-au8-effective-in-remyelination
2 · Reply
7m3835d3
7m3835d3 Feb. 2 at 3:49 PM
$CLNN hopefully we bottomed for good
0 · Reply
Mulhollandr
Mulhollandr Feb. 1 at 6:40 PM
$CLNN slide 12… All I’m saying is there are real hurdles if you want to focus on risks. But the bullish case is that ongoing FDA engagement is constructive, combo therapy is likely the future of ALS treatment, and there’s already subtle support for that in the data (including with riluzole, thanks for pointing that out). If the FDA’s aligned on survival + biomarkers for an accelerated path, that’s the signal people care about.
1 · Reply
Aawilliam2003
Aawilliam2003 Feb. 1 at 4:51 PM
$CLNN took another closer look at the data released on Dec 3rd. On slide 12 it shows the change in NFL vs matched controls. Interestingly, patients on background Riluzole and CNM-AU8 showed highly stat sig reductions in NFL (p=.016). But those just on CNM-AU8 did not show a reduction (p=.911). Isn’t this damning evidence that questions the effectiveness of the drug?
1 · Reply
Aawilliam2003
Aawilliam2003 Jan. 31 at 6:56 PM
$CLNN I think this price action is is part due to the fact that the FDA has become completely unpredictable over the past year. Several CRLs back to back that came without any real explanation, or actually cited deficiencies that were 100% contradictory to their prior guidance to the sponser. How could you have any faith here at all despite the good survival data? I see people on here talking about Vegas- that’s what biotech has become. Spin the wheel and pray
1 · Reply
Latest News on CLNN
Clene to Present at the Emerging Growth Conference

Jan 16, 2026, 8:30 AM EST - 18 days ago

Clene to Present at the Emerging Growth Conference


Clene to Provide CNM-Au8® ALS Program Update

Dec 2, 2025, 5:39 PM EST - 2 months ago

Clene to Provide CNM-Au8® ALS Program Update


Clene to Present at the Canaccord 45th Annual Growth Conference

Aug 5, 2025, 8:30 AM EDT - 6 months ago

Clene to Present at the Canaccord 45th Annual Growth Conference


Clene to Present at the 37TH Annual Roth Conference

Mar 6, 2025, 8:30 AM EST - 11 months ago

Clene to Present at the 37TH Annual Roth Conference


Clene Announces 1-for-20 Reverse Stock Split

Jul 9, 2024, 8:00 AM EDT - 1 year ago

Clene Announces 1-for-20 Reverse Stock Split


Clene to Present at Upcoming May Conferences

May 14, 2024, 8:00 AM EDT - 1 year ago

Clene to Present at Upcoming May Conferences


Clene to Present at Upcoming September Conferences

Aug 30, 2023, 8:20 AM EDT - 2 years ago

Clene to Present at Upcoming September Conferences


Chris150
Chris150 Feb. 3 at 9:12 PM
$CLNN According to a newly published Form 144 SEC Filing, Chidozie will sell another 60.842 shares. Feel free to make any corrections if you like. https://www.sec.gov/Archives/edgar/data/1822791/000162828026004957/xsl144X01/primary_doc.xml
1 · Reply
Mulhollandr
Mulhollandr Feb. 3 at 6:41 PM
$CLNN just reminding everyone. Rob says February on this call. FDA type C happens any day now.
0 · Reply
Ravery
Ravery Feb. 3 at 1:27 PM
$CLNN At this point Chidozie is just a constant drag on the stock. If he is looking to unload a large chunk of shares why not reach out to a small fund or another large investor and work out a block trade? Maybe he was unable to do so, or maybe the company pissed him off and this is a form of retaliation. Investors sell for lots of reasons, but how they sell matters. Consistently dumping smaller blocks on an illiquid stock regardless of price is a bad look. The Matlin buy on 1/13 was positive, but that is being swamped by all the sell orders. The market hates uncertainty and today's stock price reflects that.
1 · Reply
Mulhollandr
Mulhollandr Feb. 3 at 12:16 AM
$CLNN still a bit of a mystery here bc chidozie sold more than the form 144 allows. I’m frankly at a loss. Unless the sales on 12/3 and 12/4 don’t count as part of the form 144. If that’s the case then he still has 100k shares to sell. Honestly I do not know. Anyone have any thoughts?
1 · Reply
7m3835d3
7m3835d3 Feb. 2 at 11:20 PM
$CLNN here we go, this explains it, and now it’s time to go up https://invest.clene.com/static-files/b085192e-0b00-43a1-8616-4ffab367a349
0 · Reply
neuroinvestor3
neuroinvestor3 Feb. 2 at 4:24 PM
$CLNN reposting this to improve morale - “This study showed not only paraclinical evidence of remyelination and improved axonal function, but measurable improvements in previously fixed deficits that we really haven’t seen any therapy in MS do,” said Michael Barnett, MBBS, PhD. Dr. Barnett is lead author of VISIONARY-MS Long-Term Extension: A Multi-Centre, Open-Label Long-Term Extension Study of CNM-Au8 in Patients with Stable Relapsing Multiple Sclerosis. “We saw an improvement and this was, for me, very unexpected,” said Dr. Barnett, professor of neurology at the Brain and Mind Centre, the University of Sydney, and Royal Prince Alfred Hospital, Sydney. “This therapy does not regenerate nerves or axons, but I suspect what it is doing is improving axonal function and therefore allowing electrical conduction through those nerve fibers that contribute to the greater amplitude of the response.” https://www.medcentral.com/neurology/ms/multiple-sclerosis-study-shows-cnm-au8-effective-in-remyelination
2 · Reply
7m3835d3
7m3835d3 Feb. 2 at 3:49 PM
$CLNN hopefully we bottomed for good
0 · Reply
Mulhollandr
Mulhollandr Feb. 1 at 6:40 PM
$CLNN slide 12… All I’m saying is there are real hurdles if you want to focus on risks. But the bullish case is that ongoing FDA engagement is constructive, combo therapy is likely the future of ALS treatment, and there’s already subtle support for that in the data (including with riluzole, thanks for pointing that out). If the FDA’s aligned on survival + biomarkers for an accelerated path, that’s the signal people care about.
1 · Reply
Aawilliam2003
Aawilliam2003 Feb. 1 at 4:51 PM
$CLNN took another closer look at the data released on Dec 3rd. On slide 12 it shows the change in NFL vs matched controls. Interestingly, patients on background Riluzole and CNM-AU8 showed highly stat sig reductions in NFL (p=.016). But those just on CNM-AU8 did not show a reduction (p=.911). Isn’t this damning evidence that questions the effectiveness of the drug?
1 · Reply
Aawilliam2003
Aawilliam2003 Jan. 31 at 6:56 PM
$CLNN I think this price action is is part due to the fact that the FDA has become completely unpredictable over the past year. Several CRLs back to back that came without any real explanation, or actually cited deficiencies that were 100% contradictory to their prior guidance to the sponser. How could you have any faith here at all despite the good survival data? I see people on here talking about Vegas- that’s what biotech has become. Spin the wheel and pray
1 · Reply
GenX420
GenX420 Jan. 30 at 8:14 PM
$CLNN This is getting painful. Not having any money to buy more...but at the same time it keeps dropping.
0 · Reply
LXP
LXP Jan. 30 at 7:15 PM
$CLNN the fact this hasn't been pushed down further today tells me we have found the bottom sans news.
0 · Reply
neuroinvestor3
neuroinvestor3 Jan. 30 at 2:51 PM
$CLNN i want to see EAP data on PALS disease progression for the newly diagnosed… will that be presented to the FDA? also, remember the optimism and joy when this was at $13? lets get that back!
1 · Reply
aletz
aletz Jan. 30 at 1:03 PM
$CLNN On top of this week's AI scanner https://www.biostockinfo.com/biotech-catalyst-ai-scanner-february-wk1/
0 · Reply
GJ_Rockabilt
GJ_Rockabilt Jan. 30 at 11:41 AM
$CLNN Today is last day to sign up to for FREE Warrants with every Share of Cancer fighting $TPST . Acquisition in process. Do your own Due Diligence.
0 · Reply
GJ_Rockabilt
GJ_Rockabilt Jan. 30 at 11:15 AM
$CLNN Today is last day since up to for FREE Warrants with every Share of Cancer fighting $TPST . Acquisition in process. Do your own Due Diligence.
0 · Reply
LXP
LXP Jan. 29 at 8:03 PM
$CLNN this price movement fcks with even the most rational scientifically- based investors. If there is something to this, we will hear at the close or before open tomorrow. I agree with prior posts-- timing doesn't make sense for any bad news.
2 · Reply
neuroinvestor3
neuroinvestor3 Jan. 29 at 6:45 PM
$CLNN macro trends not good for pre-revenue small/microcaps.. especially those with short cash runway. insider dumping (Chidozie) combined with speculators who probably bought at $10 cutting their losses is apparent. As is the risk of a government shutdown again and HHS/FDA staffing issues. Are there enough competent feds left to have a meeting, review data, move forward with AA decision? Do people think that rising gold prices impact CNM-Au8 production costs? FYI... an ounce of gold is around 850 doses.
0 · Reply
Takeover24
Takeover24 Jan. 29 at 5:17 PM
$CLNN Hard to reconcile the fact that 3 sophisticated biotech funds bought in at $6.50 just a few weeks ago and stock is now trading in low $4's heading into pivotal FDA news as to whether the NDA can be filed. Those funds were obv betting on "yes" and now the market appears to be pricing in a "no" or at least a "not yet as we need more info" (meaning FDA does not close the door but requests new analyses that further delays the timeline and will require more cash)
1 · Reply
Ravery
Ravery Jan. 29 at 4:23 PM
$CLNN What happened for ransoms? He was an active poster on this board and a good one. He erased all of his prior messages and disappeared.
1 · Reply
Acx21
Acx21 Jan. 29 at 3:51 PM
$CLNN just told a friend to calm down. Don't rate a company by its stock price. Rather focus on facts. And fact is that CLNN has kept delivering good news and handled the capital requirements very good. The possibility of a successful NDA/acceralerated approval is way higher than in October. But the stock price isnt. It's contradictory but well, thats part of the small caps game
1 · Reply
Takeover24
Takeover24 Jan. 29 at 3:50 PM
$CLNN Management posted the following on LinkedIn yesterday. Hard to believe they would do this if Type C already took place and outcome was negative... Clene’s recent analyses demonstrate strong alignment with the FDA’s accelerated approval framework for ALS. Across large, independent patient cohorts, longitudinal increases in neurofilament light chain (NfL) were consistently associated with higher mortality risk, while CNM-Au8 produced reproducible and statistically significant NfL reductions across multiple studies. Quantitative modeling shows that these NfL reductions are associated with improved survival, supporting NfL trajectory as a clinically meaningful biomarker to inform regulatory decision-making.
0 · Reply