Market Cap 55.51M
Revenue (ttm) 200,000.00
Net Income (ttm) -26.17M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -13,085.00%
Debt to Equity Ratio -0.25
Volume 28,800
Avg Vol 76,778
Day's Range N/A - N/A
Shares Out 12.85M
Stochastic %K 32%
Beta 0.96
Analysts Strong Sell
Price Target $32.00

Company Profile

Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The company's lead drug candidate is CNM-Au8, which is being studied in various clinical trials, including a completed Phase 2 platform trial to evaluate the safety and efficacy of CNM-Au8 in patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic...

Industry: Packaged Foods
Sector: Consumer Defensive
Phone: 801 676 9695
Website: clene.com
Address:
6550 South Millrock Drive, Suite G50, Salt Lake City, United States
LXP
LXP Aug. 21 at 10:45 PM
$CLNN how much do you think the Healy results will hurt us in the eyes of the ADCOM? Clearly, the FDA has been supportive in the construction of the NDA AA opportunity
0 · Reply
Mulhollandr
Mulhollandr Aug. 21 at 7:18 PM
$CLNN tried 3 times to post this in here but for some reason it isn’t showing up. 🤔
4 · Reply
Mulhollandr
Mulhollandr Aug. 21 at 4:39 PM
$CLNN posts haven’t been posting. So just a test here.
0 · Reply
Takeover24
Takeover24 Aug. 21 at 1:41 PM
$CLNN I have been thinking about one interesting nugget from the recent presentations that hasn't been discussed yet: Rob said they are including the MS data in the NDA at the FDA's request. Why would FDA specifically want to see the MS data as it evaluates the ALS NDA? Think about the question FDA has to answer for AA: Is the NfL signal in ALS a real biological effect that is reasonably likely to predict clinical benefit? That's where the MS data could potentially be meaningful. In MS, CNM-Au8 has shown a notable degree of concordance across multiple measures: randomized clinical data, VEP/neurophysiology, MRI/DTI and other objective measures. The primary LCLA endpoint was borderline, so this isn't a slam-dunk Phase 3 efficacy package. But multiple independent measures moving in the same direction provides evidence that CNM-Au8 is doing something biologically meaningful in the human nervous system. (con't)
2 · Reply
neuroinvestor3
neuroinvestor3 Aug. 21 at 2:00 AM
$CLNN Board Chair and billionaire David Matlin owns approximately 477,824 direct shares of Clene Inc. (CLNN).📊 Breakdown of HoldingsDirect Ownership: 477,824 shares (following his purchase of 33,333 shares on January 13, 2026).Indirect Ownership: 7,500 shares held via the Matlin Family Trust 2020 (where he serves as trustee).Total Stake: Roughly 3.74% ownership of the company's common stock. I’m guessing he’ll make sure they have the resources to get through FDA approval.
2 · Reply
Woodman7
Woodman7 Aug. 20 at 11:40 PM
$CLNN - 😢😢 https://share.google/NkSffJkcZMM9klfhN
1 · Reply
Sterling100
Sterling100 Aug. 20 at 4:01 PM
$CLNN At $4.21 and ~$54M market cap, work backwards to what the market is implying. Approval scenario: sell-side targets sit around $31–32 (Benchmark at $31, consensus ~$32.20). Those aren't crazy — an approved ALS drug at Relyvrio-like pricing supports a $500M–1.5B enterprise value, and even on a diluted count of ~20M shares that lands in the $25–75 range. CRL scenario: probably $1.00–1.50, maybe lower. Run it. At a 25% approval probability: 0.25 × $35 + 0.75 × $1$9.50. At 15%: 0.15 × $35 + 0.85 × $1$6.10. Both above $4.21. The market at $4.21 is implying roughly 10–13% approval odds. But the real odds is around 50%. Even if you would put it somewhere around 20–30%, the stock is cheap at these levels and the expected value is positive. Boxer, Vivo, Coastlands got shares at $6.50 in Jan; a single buyer took 1M shares at $7 in April/May. Also, they are not going to go a full-blown offering, maybe around $10M -$20 m to cover until 1H 2027. I wouldn't mind such scenario, would you?
4 · Reply
BenKaitz
BenKaitz Aug. 20 at 3:04 PM
$CLNN $EYPT $ALT are the three bio’s I’m scooping shares of. All three have tremendous upside and are undervalued in my opinion. There are others, but those are my top three currently.
1 · Reply
Woodman7
Woodman7 Aug. 20 at 10:50 AM
$CLNN - The next $MRNA ?? “Clene plans to submit an NDA for CNM-Au8 in ALS at the start of Q4 after completing FDA-requested analyses linking neurofilament light-chain changes to clinical benefits. The FDA indicated the data may support accelerated approval review if that connection is demonstrated. Among patients whose neurofilament levels declined or stabilized, Clene reported a 74% lower 12-month mortality risk versus controls, along with statistically significant improvements in ALS functional scores and breathing capacity. The company expects an FDA filing decision and potential PDUFA date by year-end, with a possible commercialization decision by early summer 2027; its safety database represents approximately 1,250 patient-years of exposure.” $MRK
3 · Reply
Woodman7
Woodman7 Aug. 20 at 10:46 AM
$CLNN https://finance.yahoo.com/healthcare/articles/clene-eyes-q4-nda-als-220316789.html
0 · Reply
Latest News on CLNN
Clene Transcript: Emerging Growth Conference

Aug 19, 2026, 3:10 PM EDT - 4 days ago

Clene Transcript: Emerging Growth Conference


Clene to Present at the Emerging Growth Conference

Aug 17, 2026, 8:30 AM EDT - 6 days ago

Clene to Present at the Emerging Growth Conference


Clene reports Q2 EPS ($1.08), consensus (26c)

2026-08-16T13:18:33.000Z - 7 days ago

Clene reports Q2 EPS ($1.08), consensus (26c)


Clene Quarterly report: Q2 2026

Aug 14, 2026, 7:00 AM EDT - 9 days ago

Clene Quarterly report: Q2 2026


Clene Earnings release: Q2 2026

Aug 14, 2026, 7:00 AM EDT - 9 days ago

Clene Earnings release: Q2 2026


Clene to Present at The Canaccord 46th Annual Growth Conference

Jul 29, 2026, 8:30 AM EDT - 25 days ago

Clene to Present at The Canaccord 46th Annual Growth Conference


Clene reports Q1 EPS (69c), consensus (70c)

2026-05-14T16:30:10.000Z - 3 months ago

Clene reports Q1 EPS (69c), consensus (70c)


Clene Quarterly report: Q1 2026

May 14, 2026, 7:00 AM EDT - 3 months ago

Clene Quarterly report: Q1 2026


Clene Earnings release: Q1 2026

May 14, 2026, 7:00 AM EDT - 3 months ago

Clene Earnings release: Q1 2026


Clene price target raised to $50 from $48 at Canaccord

2026-05-08T11:23:32.000Z - 3 months ago

Clene price target raised to $50 from $48 at Canaccord


Clene Transcript: Emerging Growth Conference 92

May 6, 2026, 3:25 PM EDT - 3 months ago

Clene Transcript: Emerging Growth Conference 92


Clene to Present at Upcoming May Conferences

May 5, 2026, 8:00 AM EDT - 3 months ago

Clene to Present at Upcoming May Conferences


Clene Proxy statement: Proxy filing

Apr 10, 2026, 8:00 AM EDT - 4 months ago

Clene Proxy statement: Proxy filing


Clene Proxy statement: Proxy filing

Apr 10, 2026, 8:00 AM EDT - 4 months ago

Clene Proxy statement: Proxy filing


Clene reports FY25 EPS ($2.65), consensus ($2.35)

2026-03-12T12:12:18.000Z - 5 months ago

Clene reports FY25 EPS ($2.65), consensus ($2.35)


Clene Annual report: Q4 2025

Mar 12, 2026, 8:00 AM EDT - 5 months ago

Clene Annual report: Q4 2025


Clene Annual report: Q4 2025

Mar 12, 2026, 8:00 AM EDT - 5 months ago

Clene Annual report: Q4 2025


Clene Earnings release: Q4 2025

Mar 12, 2026, 8:00 AM EDT - 5 months ago

Clene Earnings release: Q4 2025


Clene Transcript: Emerging Growth Virtual Conference

Feb 25, 2026, 1:45 PM EST - 6 months ago

Clene Transcript: Emerging Growth Virtual Conference


Clene issues letter to shareholders on CNM-Au8 2026 catalysts

2026-02-24T13:13:07.000Z - 6 months ago

Clene issues letter to shareholders on CNM-Au8 2026 catalysts


Clene Transcript: Emerging Growth Conference 89

Jan 21, 2026, 3:10 PM EST - 7 months ago

Clene Transcript: Emerging Growth Conference 89


Clene announces over $28M registered direct offering

2026-01-09T13:41:01.000Z - 8 months ago

Clene announces over $28M registered direct offering


Clene Announces Registered Direct Offering of Over $28 Million

Jan 9, 2026, 8:30 AM EST - 8 months ago

Clene Announces Registered Direct Offering of Over $28 Million


Clene Transcript: Emerging Growth Conference 88

Dec 10, 2025, 4:25 PM EST - 9 months ago

Clene Transcript: Emerging Growth Conference 88


Clene price target raised to $30 from $20 at Maxim

2025-12-03T18:15:36.000Z - 9 months ago

Clene price target raised to $30 from $20 at Maxim


Clene Transcript: Study Update

Dec 3, 2025, 8:30 AM EST - 9 months ago

Clene Transcript: Study Update


Clene Press release: Study Update

Dec 3, 2025, 8:30 AM EST - 9 months ago

Clene Press release: Study Update


Clene Slides: Study Update

Dec 3, 2025, 8:30 AM EST - 9 months ago

Clene Slides: Study Update


Clene to Provide CNM-Au8® ALS Program Update

Dec 2, 2025, 5:39 PM EST - 9 months ago

Clene to Provide CNM-Au8® ALS Program Update


Clene reports Q3 EPS (85c), consensus (56c)

2025-11-13T13:10:28.000Z - 10 months ago

Clene reports Q3 EPS (85c), consensus (56c)


Clene sees cash runway into 2Q26

2025-11-13T13:10:16.000Z - 10 months ago

Clene sees cash runway into 2Q26


Clene Earnings release: Q3 2025

Nov 13, 2025, 8:00 AM EST - 10 months ago

Clene Earnings release: Q3 2025


Clene Quarterly report: Q3 2025

Nov 13, 2025, 8:00 AM EST - 10 months ago

Clene Quarterly report: Q3 2025


Clene Transcript: Emerging Growth Conference

Oct 23, 2025, 3:10 PM EDT - 10 months ago

Clene Transcript: Emerging Growth Conference


Clene announces presentation of combined REPAIR-MS results

2025-09-25T12:10:32.000Z - 11 months ago

Clene announces presentation of combined REPAIR-MS results


Clene price target lowered to $31 from $33 at Benchmark

2025-09-10T12:00:43.000Z - 1 year ago

Clene price target lowered to $31 from $33 at Benchmark


Clene Registration statement: Registration Filing

Sep 5, 2025, 8:00 AM EDT - 1 year ago

Clene Registration statement: Registration Filing


Clene Transcript: Emerging Growth Conference 85

Aug 20, 2025, 2:20 PM EDT - 1 year ago

Clene Transcript: Emerging Growth Conference 85


Clene price target lowered to $48 from $83 at Canaccord

2025-08-18T10:40:11.000Z - 1 year ago

Clene price target lowered to $48 from $83 at Canaccord


Clene Earnings release: Q2 2025

Aug 14, 2025, 8:30 AM EDT - 1 year ago

Clene Earnings release: Q2 2025


Clene Quarterly report: Q2 2025

Aug 14, 2025, 8:30 AM EDT - 1 year ago

Clene Quarterly report: Q2 2025


Clene Transcript: Emerging Growth Conference 84

Jul 17, 2025, 3:10 PM EDT - 1 year ago

Clene Transcript: Emerging Growth Conference 84


Clene Transcript: Q2 Virtual Investor Summit Event

Jun 10, 2025, 1:00 PM EDT - 1 year ago

Clene Transcript: Q2 Virtual Investor Summit Event


Clene Transcript: Emerging Growth Conference 82

May 21, 2025, 3:10 PM EDT - 1 year ago

Clene Transcript: Emerging Growth Conference 82


Clene Slides: Investor Presentation

May 14, 2025, 7:00 AM EDT - 1 year ago

Clene Slides: Investor Presentation


Clene Earnings release: Q1 2025

May 7, 2025, 8:00 AM EDT - 1 year ago

Clene Earnings release: Q1 2025


Clene Quarterly report: Q1 2025

May 7, 2025, 8:00 AM EDT - 1 year ago

Clene Quarterly report: Q1 2025


Clene Proxy statement: Proxy Filing

Apr 8, 2025, 8:00 AM EDT - 1 year ago

Clene Proxy statement: Proxy Filing


Clene Proxy statement: Proxy Filing

Apr 8, 2025, 8:00 AM EDT - 1 year ago

Clene Proxy statement: Proxy Filing


Clene Proxy statement: Proxy Filing

Mar 28, 2025, 8:00 AM EDT - 1 year ago

Clene Proxy statement: Proxy Filing


Clene Annual report: Q4 2024

Mar 24, 2025, 9:00 AM EDT - 1 year ago

Clene Annual report: Q4 2024


Clene Earnings release: Q4 2024

Mar 24, 2025, 9:00 AM EDT - 1 year ago

Clene Earnings release: Q4 2024


Clene Registration statement: Registration Filing

Mar 24, 2025, 8:00 AM EDT - 1 year ago

Clene Registration statement: Registration Filing


Clene Transcript: 37th Annual ROTH Conference

Mar 18, 2025, 12:30 PM EDT - 1 year ago

Clene Transcript: 37th Annual ROTH Conference


Clene to Present at the 37TH Annual Roth Conference

Mar 6, 2025, 8:30 AM EST - 1 year ago

Clene to Present at the 37TH Annual Roth Conference


Clene Registration statement: Registration Filing

Jan 24, 2025, 7:00 AM EST - 1 year ago

Clene Registration statement: Registration Filing


Clene Slides: Investor Presentation

Dec 10, 2024, 7:00 AM EST - 1 year ago

Clene Slides: Investor Presentation


Clene Quarterly report: Q3 2024

Nov 13, 2024, 7:00 AM EST - 1 year ago

Clene Quarterly report: Q3 2024


Clene Earnings release: Q3 2024

Nov 13, 2024, 7:00 AM EST - 1 year ago

Clene Earnings release: Q3 2024


Clene Registration statement: Registration Filing

Nov 13, 2024, 7:00 AM EST - 1 year ago

Clene Registration statement: Registration Filing


Clene Quarterly report: Q2 2024

Aug 7, 2024, 7:00 AM EDT - 2 years ago

Clene Quarterly report: Q2 2024


Clene Earnings release: Q2 2024

Aug 7, 2024, 7:00 AM EDT - 2 years ago

Clene Earnings release: Q2 2024


Clene Announces 1-for-20 Reverse Stock Split

Jul 9, 2024, 8:00 AM EDT - 2 years ago

Clene Announces 1-for-20 Reverse Stock Split


Clene Quarterly report: Q1 2024

May 8, 2024, 7:00 AM EDT - 2 years ago

Clene Quarterly report: Q1 2024


Clene Earnings release: Q1 2024

May 8, 2024, 7:00 AM EDT - 2 years ago

Clene Earnings release: Q1 2024


Clene Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Clene Proxy statement: Proxy Filing


Clene Proxy statement: Proxy Filing

Apr 16, 2024, 8:00 AM EDT - 2 years ago

Clene Proxy statement: Proxy Filing


Clene Proxy statement: Proxy Filing

Apr 5, 2024, 8:00 AM EDT - 2 years ago

Clene Proxy statement: Proxy Filing


Clene Annual report: Q4 2023

Mar 13, 2024, 8:00 AM EDT - 2 years ago

Clene Annual report: Q4 2023


Clene Earnings release: Q4 2023

Mar 13, 2024, 8:00 AM EDT - 2 years ago

Clene Earnings release: Q4 2023


LXP
LXP Aug. 21 at 10:45 PM
$CLNN how much do you think the Healy results will hurt us in the eyes of the ADCOM? Clearly, the FDA has been supportive in the construction of the NDA AA opportunity
0 · Reply
Mulhollandr
Mulhollandr Aug. 21 at 7:18 PM
$CLNN tried 3 times to post this in here but for some reason it isn’t showing up. 🤔
4 · Reply
Mulhollandr
Mulhollandr Aug. 21 at 4:39 PM
$CLNN posts haven’t been posting. So just a test here.
0 · Reply
Takeover24
Takeover24 Aug. 21 at 1:41 PM
$CLNN I have been thinking about one interesting nugget from the recent presentations that hasn't been discussed yet: Rob said they are including the MS data in the NDA at the FDA's request. Why would FDA specifically want to see the MS data as it evaluates the ALS NDA? Think about the question FDA has to answer for AA: Is the NfL signal in ALS a real biological effect that is reasonably likely to predict clinical benefit? That's where the MS data could potentially be meaningful. In MS, CNM-Au8 has shown a notable degree of concordance across multiple measures: randomized clinical data, VEP/neurophysiology, MRI/DTI and other objective measures. The primary LCLA endpoint was borderline, so this isn't a slam-dunk Phase 3 efficacy package. But multiple independent measures moving in the same direction provides evidence that CNM-Au8 is doing something biologically meaningful in the human nervous system. (con't)
2 · Reply
neuroinvestor3
neuroinvestor3 Aug. 21 at 2:00 AM
$CLNN Board Chair and billionaire David Matlin owns approximately 477,824 direct shares of Clene Inc. (CLNN).📊 Breakdown of HoldingsDirect Ownership: 477,824 shares (following his purchase of 33,333 shares on January 13, 2026).Indirect Ownership: 7,500 shares held via the Matlin Family Trust 2020 (where he serves as trustee).Total Stake: Roughly 3.74% ownership of the company's common stock. I’m guessing he’ll make sure they have the resources to get through FDA approval.
2 · Reply
Woodman7
Woodman7 Aug. 20 at 11:40 PM
$CLNN - 😢😢 https://share.google/NkSffJkcZMM9klfhN
1 · Reply
Sterling100
Sterling100 Aug. 20 at 4:01 PM
$CLNN At $4.21 and ~$54M market cap, work backwards to what the market is implying. Approval scenario: sell-side targets sit around $31–32 (Benchmark at $31, consensus ~$32.20). Those aren't crazy — an approved ALS drug at Relyvrio-like pricing supports a $500M–1.5B enterprise value, and even on a diluted count of ~20M shares that lands in the $25–75 range. CRL scenario: probably $1.00–1.50, maybe lower. Run it. At a 25% approval probability: 0.25 × $35 + 0.75 × $1$9.50. At 15%: 0.15 × $35 + 0.85 × $1$6.10. Both above $4.21. The market at $4.21 is implying roughly 10–13% approval odds. But the real odds is around 50%. Even if you would put it somewhere around 20–30%, the stock is cheap at these levels and the expected value is positive. Boxer, Vivo, Coastlands got shares at $6.50 in Jan; a single buyer took 1M shares at $7 in April/May. Also, they are not going to go a full-blown offering, maybe around $10M -$20 m to cover until 1H 2027. I wouldn't mind such scenario, would you?
4 · Reply
BenKaitz
BenKaitz Aug. 20 at 3:04 PM
$CLNN $EYPT $ALT are the three bio’s I’m scooping shares of. All three have tremendous upside and are undervalued in my opinion. There are others, but those are my top three currently.
1 · Reply
Woodman7
Woodman7 Aug. 20 at 10:50 AM
$CLNN - The next $MRNA ?? “Clene plans to submit an NDA for CNM-Au8 in ALS at the start of Q4 after completing FDA-requested analyses linking neurofilament light-chain changes to clinical benefits. The FDA indicated the data may support accelerated approval review if that connection is demonstrated. Among patients whose neurofilament levels declined or stabilized, Clene reported a 74% lower 12-month mortality risk versus controls, along with statistically significant improvements in ALS functional scores and breathing capacity. The company expects an FDA filing decision and potential PDUFA date by year-end, with a possible commercialization decision by early summer 2027; its safety database represents approximately 1,250 patient-years of exposure.” $MRK
3 · Reply
Woodman7
Woodman7 Aug. 20 at 10:46 AM
$CLNN https://finance.yahoo.com/healthcare/articles/clene-eyes-q4-nda-als-220316789.html
0 · Reply
josh77
josh77 Aug. 20 at 2:17 AM
$CLNN i hope this works out one day...
1 · Reply
BenKaitz
BenKaitz Aug. 19 at 7:53 PM
0 · Reply
Acx21
Acx21 Aug. 19 at 7:32 PM
$CLNN summing up the very recent emerging growth call: Most importany, Morgan wasnt part of it, consequently no news about the measure to be expected to close the cash gap up to the FDA acceptance of the NDA. Still, the call was very encouraging. Rob again proved himself being a convincing speaker. For my understanding he basically said: The last 90 days we have been working on the NDA, clearing the FDA checklist what they want us to prove step by step. And they succeeded in every point. He seemed like there is no doubt in the NDA acceptance and probably also not in the accelerated approval (which of course he didnt mention like this). He mentioned a potential PDUFA date in early summer 2027. He also specifically pointed out, that CLNN succeeded in proving things other company failed in ALS for decades. All in all, I feel like if the manage to handle the financial issues, it all about waiting for summer 2027 for our big paycheck. Any thoughts (especially different ones) about it?
1 · Reply
Chris150
Chris150 Aug. 19 at 7:32 PM
$CLNN Clene Inc. presentation at Emerging Growth Conference 95. https://www.youtube.com/watch?v=rx2vb6-QD4I
0 · Reply
Bbbb44444
Bbbb44444 Aug. 19 at 7:17 PM
$CLNN For those smarter than me, how do you feel about the current risk of dilution and their ability to clear the bar the FDA has set (showing that the magnitude of NfL change is reasonably likely to predict clinical benefit)?
1 · Reply
BenKaitz
BenKaitz Aug. 19 at 6:59 PM
$CLNN 1,000 shares added today
0 · Reply
Mulhollandr
Mulhollandr Aug. 19 at 2:30 PM
$CLNN for what it’s worth. Scoggin Management doubled their holding in Q2 from 300k shares to 600k shares. They are a fairly sophisticated firm and have been around for 40 years or so. Just nice to see that is not just us in the peanut gallery here that are noticing Clene.
0 · Reply
Takeover24
Takeover24 Aug. 19 at 1:46 PM
$CLNN So AMLX fails its Phase 3 ALS trial and pulls its ALS drug from the market. It then acquires an asset out of bankruptcy for $35M—and that asset has now helped turn the company into a ~$4B market cap story just a few years later. Meanwhile, CLNN has defied the odds to advance CNM-Au8 this far with the FDA and is now on the cusp of filing its NDA. I believe the odds of Accelerated Approval by mid-2027 are >50%, particularly given that the FDA has essentially provided a roadmap for what it needs to see and CLNN appears to have delivered on that roadmap. And yet CLNN remains stuck at roughly a $50M market cap. The AMLX story is also a reminder that cash is king in biotech. AMLX was able to build a meaningful cash position through commercialization of its ALS drug before it ultimately had to be pulled. That cash gave the company the ability to acquire another asset when the opportunity presented itself. (1/2)
1 · Reply
Sterling100
Sterling100 Aug. 19 at 1:52 AM
$CLNN How is this thing $4 with a $54M valuation? The execs’ personal real estate probably outweighs the value of the entire business. One of them could sell a house and scoop up the whole company. I might tap in a bit tomorrow just for fun.
0 · Reply
Bobfree
Bobfree Aug. 18 at 7:43 PM
$CLNN sold half my rvmd, half went in here and half went in prqr this morning. Clene has some catching up to do.
0 · Reply
neuroinvestor3
neuroinvestor3 Aug. 18 at 7:26 PM
$CLNN Video on Coya ALS therapy - https://www.cbsnews.com/philadelphia/video/promising-research-for-als-treatment-underway-at-temple-health-in-philadelphia/
0 · Reply
neuroinvestor3
neuroinvestor3 Aug. 18 at 6:08 PM
$CLNN check out $AMLX today...nice to see them recover and pivot from their ALS experience. Also, we havent seen any our Clene bashers in awhile....good sign?
1 · Reply