Jul. 17 at 3:25 PM
$BCAB Low grade adverse effects. All (8/8) metastatic and unresectable melanoma pts safely achieved tumor reduction with evalstotug + anti-PD-1, including patients with only 1 scan, which will be further updated. It was notable that intrapatient evalstotug dose escalation safely re-attained tumor control, suggesting increasing evalstotug exposure can drive improved antitumor activity, even after months on anti-CTLA4 therapy.
https://www.researchgate.net/publication/389268223_Abstract_A107_Updated_results_from_a_study_of_evalstotug_BA3071_an_anti-CTLA-4_conditionally_active_biologic_in_melanoma