Aprea Therapeutics Inc (APRE) Stock Price, Quote & News

Company Profile

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers; and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid...

Industry: Biotechnology

Sector: Healthcare

Phone: 215 948 4119

Website: aprea.com

Address:

3805 Old Easton Road, Doylestown, United States

BootyEater69 Dec. 4 at 4:22 PM

$APRE trash

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TezBunny Dec. 4 at 12:28 PM

$APRE I told you back in September, under a dollar 🤣 We can do better than that tho, let’s tear this sucker down

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NewsAndFilings Dec. 2 at 8:23 PM

$1 Stocks to Watch: $TOON $PRSO $APRE $PNPNF $PNPN.V December 2025 More Inside https://thestreetreports.com/1-stocks-to-watch-jspr-ftel-bynd-toon-december-2025-more-inside/

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FloFloFloFlo Dec. 2 at 6:23 PM

$APRE what’s going on at this company? What are they actually doing day to day?

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topstockalerts Nov. 24 at 1:57 PM

Pre Market Top Gainers PT2 $GELS $BRLS $APRE $CHSN $VSA

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Bulltrader988 Nov. 18 at 7:55 PM

$APRE 13 G filled yesterday: LYTTON LAURENCE W 681,837 shares = 9.9 % ownership 👃👀 https://www.sec.gov/Archives/edgar/data/1105806/000093583625000708/xslSCHEDULE_13G_X01/primary_doc.xml

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NewsAndFilings Nov. 17 at 8:32 PM

$APRE 3Q25 Review & Outlook: Synthetic Lethality Programs Around The WEE1i and ATRi Continue to Progress https://thestreetreports.com/wp-content/uploads/2025/11/APRE-Report.pdf

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MsGrumpy Nov. 17 at 5:11 PM

$APRE Maxim Group: Issued A Buy Rating ($10 Price Target) Aprea Therapeutics https://thestreetreports.com/wp-content/uploads/2025/11/APRE-Report.pdf

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NewsAndFilings Nov. 13 at 12:37 PM

Yesterday's Recap: $APRE Q3 Financials $CBDL Secures Major Hemp Flower Order $KRTL Publishes Investor Presentation $KARX and Hockey Canada Partnership

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d_risk Nov. 12 at 4:30 PM

$APRE - Aprea Therapeutics, Inc. - 10Q - Updated Risk Factors APRE’s latest 10-Q flags heightened risk from paused and early-stage trials, limited clinical experience, expanded financial and regulatory uncertainties, IP and commercialization threats, global pricing pressures, and reputational risks tied to synthetic lethality therapies. #Biotechnology #MarketPricingPressure #IntellectualProperty #RegulatoryRisk #ClinicalTrials 🟢 Added 🟠 Removed https://d-risk.ai/APRE/10-Q/2025-11-12

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Aprea Therapeutics Reports Third quarter 2025 Financial Results and Provides a Clinical Update

Oct 24, 2025, 8:30 AM EDT - 6 weeks ago

Aprea Therapeutics Provides Clinical Update from ACESOT-1051 Trial Showing Early Signals of Activity for WEE1 Kinase Inhibitor APR-1051

Oct 15, 2025, 8:00 AM EDT - 7 weeks ago

Aprea Therapeutics Establishes Recommended Phase 2 Dose (RP2D) for ATRN-119, Considering Combination Therapies

Oct 14, 2025, 8:00 AM EDT - 7 weeks ago

Aprea Therapeutics Announces Presentations at EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics

Aug 28, 2025, 8:30 AM EDT - 3 months ago

Aprea Therapeutics to Present at H.C. Wainwright Global Investment Conference

Aug 12, 2025, 8:00 AM EDT - 4 months ago

Aprea Therapeutics Reports Second Quarter 2025 Financial Results and Provides a Clinical Update

Jun 25, 2025, 9:00 AM EDT - 5 months ago

Aprea Reports Anti-Proliferative Results and Promising Early-Stage Clinical Data for Next-Generation WEE1 Inhibitor, APR-1051, in HPV+ Head and Neck Squamous Cell Carcinoma (HNSCC) in Collaboration with MD Anderson Cancer Center

May 14, 2025, 8:00 AM EDT - 7 months ago

Aprea Therapeutics Reports First Quarter 2025 Financial Results and Provides a Clinical Update

Mar 31, 2025, 8:30 AM EDT - 8 months ago

Aprea Therapeutics Announces Dosing of Patient with HPV+ Head and Neck Squamous Cell Carcinoma (HNSCC) in Ongoing ACESOT-1051 Trial

Mar 25, 2025, 8:30 AM EDT - 9 months ago

Aprea Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update

Mar 11, 2025, 8:30 AM EDT - 9 months ago

Aprea Therapeutics Announces Agreement with MD Anderson Cancer Center to Explore APR-1051 as a Potential Treatment for Head and Neck Squamous Cell Carcinoma (HNSCC)

Feb 5, 2025, 8:00 AM EST - 10 months ago

Aprea Therapeutics Announces Strategic IP Portfolio Evolution in DNA Damage Response (DDR) Cancer Therapeutics

Dec 11, 2024, 8:30 AM EST - 1 year ago

Aprea Therapeutics Announces Twice Daily (BID) Dosing of Patients in ABOYA-119 Clinical Trial of ATRN-119 to Potentially Optimize Clinical Outcomes and Strengthen Clinical Path Forward

Oct 23, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Presents Preliminary Findings on Oral WEE1 Inhibitor APR-1051 at EORTC-NCI-AACR International Conference on Molecular Targets and Therapeutics

Oct 14, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics to Present at Maxim 2024 Healthcare Virtual Summit

Oct 10, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Announces Presentations at EORTC-NCI-AACR International Conference on Molecular Targets and Therapeutics

Oct 9, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Engages Philippe Pultar, MD to Serve as Senior Medical Advisor and Lead WEE1 Clinical Development

Sep 9, 2024, 5:15 PM EDT - 1 year ago

UPDATE - Aprea Therapeutics to Present at the H.C. Wainwright Annual Global Investment Conference

Sep 9, 2024, 4:05 PM EDT - 1 year ago

Aprea Therapeutics to Present at the H.C. Wainwright Annual Global Investment Conference

Aug 12, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Reports Second Quarter 2024 Financial Results and Provides Business Update

Jun 21, 2024, 8:00 AM EDT - 1 year ago

Aprea Therapeutics to Host Virtual KOL Event on APR-1051, a Highly Selective and Potentially Best-in-Class Oral WEE1 Inhibitor, on Monday, June 24, 2024

Jun 17, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Announces First Patient Dosed in ACESOT-1051 Phase 1 Trial Evaluating Oral WEE1 Inhibitor APR-1051

May 28, 2024, 8:45 AM EDT - 1 year ago

Aprea Therapeutics Announces that Safety Review Committee (SRC) Endorses Dosing of Patients with ATRN-119 at 800 mg Once Daily in Ongoing ABOYA-119 Clinical Trial

May 14, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Reports First quarter 2024 Financial Results and Provides a Business Update

May 13, 2024, 4:01 PM EDT - 1 year ago

Aprea Therapeutics to Attend the 2024 RBC Capital Markets Global Healthcare Conference

May 2, 2024, 9:15 AM EDT - 1 year ago

Aprea Therapeutics Announces Appointment of Nadeem Q. Mirza, M.D.

Apr 10, 2024, 12:00 PM EDT - 1 year ago

Aprea Therapeutics Announces Presentations on its Next Generation WEE1 Inhibitor, APR-1051, and A Novel Macrocyclic ATR Inhibitor, ATRN-119, at AACR Annual Meeting 2024

Mar 26, 2024, 7:45 AM EDT - 1 year ago

Aprea Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides a Business Update

Mar 14, 2024, 7:48 AM EDT - 1 year ago

Karolinska Development's portfolio company Aprea Therapeutics receives FDA IND approval and secures funding of USD 34 million

Mar 11, 2024, 8:30 AM EDT - 1 year ago

Aprea Therapeutics Announces Private Placement Financing of up to $34.0 Million

Mar 11, 2024, 8:29 AM EDT - 1 year ago

Aprea Therapeutics Announces FDA Clearance of IND for APR-1051, its Next Generation WEE1 Kinase Inhibitor for Cyclin E Overexpressing Cancers

Mar 5, 2024, 4:45 PM EST - 1 year ago

Aprea Therapeutics Announces Acceptance of Abstracts at American Association of Cancer Research Annual Meeting 2024

Feb 6, 2024, 8:01 AM EST - 1 year ago

Aprea Therapeutics Announces Submission of IND Application for APR-1051, a Next Generation WEE1 Kinase Inhibitor

Jan 30, 2024, 8:00 AM EST - 2 years ago

Aprea Therapeutics to Present at DDR Inhibitors Summit 2024

Jan 4, 2024, 4:05 PM EST - 2 years ago

Aprea Therapeutics Provides Corporate Update and Announces Development Plans for 2024

Nov 9, 2023, 4:05 PM EST - 2 years ago

Aprea Therapeutics Reports Third Quarter 2023 Financial Results and Provides a Business Update

Oct 16, 2023, 8:30 AM EDT - 2 years ago

Aprea Unveils Initial Clinical Data on ATRi, ATRN-119, and Pre-Clinical Data on WEE1i, ATRN-1051, at AACR-NCI-EORTC International Conference Supporting Highly Differentiated Synthetic Lethality Portfolio

Sep 19, 2023, 8:00 AM EDT - 2 years ago

Aprea Therapeutics Announces Two Posters at the Upcoming 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Sep 11, 2023, 8:00 AM EDT - 2 years ago

Aprea Announces Preclinical Data Supporting Highly Differentiated WEE1 Inhibitor, ATRN-1051, Relative To Other WEE1 Inhibitors

Sep 6, 2023, 4:05 PM EDT - 2 years ago

Aprea Therapeutics to Present at the H.C. Wainwright 25th Annual Global Investment Conference

Aug 24, 2023, 7:30 AM EDT - 2 years ago

Aprea Therapeutics Appoints Dr. Jean-Pierre Bizzari to its Board of Directors and Names Dr. Richard Peters as Chairman

Aug 10, 2023, 7:30 AM EDT - 2 years ago

Aprea Therapeutics Reports Second Quarter 2023 Financial Results and Provides Update on Business Operations

Jun 14, 2023, 8:00 AM EDT - 2 years ago

Aprea Therapeutics to Present at Maxim Virtual Healthcare Conference

May 30, 2023, 8:30 AM EDT - 2 years ago

Aprea Therapeutics to Present at BIO International Convention

May 15, 2023, 4:05 PM EDT - 2 years ago

Aprea Therapeutics Reports First Quarter 2023 Financial Results and Provides Update on Business Operations

May 8, 2023, 8:00 AM EDT - 2 years ago

Aprea Therapeutics Appoints Gabriela Gruia, M.D. to Board of Directors

Mar 30, 2023, 4:05 PM EDT - 2 years ago

Aprea Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Update on Business Operations

Mar 16, 2023, 8:00 AM EDT - 2 years ago

Aprea Therapeutics Announces Presentation of Preclinical Data on Pipeline Programs at the AACR 2023 Annual Meeting

Mar 1, 2023, 4:05 PM EST - 3 years ago

Aprea Therapeutics Regains Compliance with Nasdaq Minimum Bid Price Requirement

Feb 27, 2023, 4:05 PM EST - 3 years ago

Aprea Therapeutics Announces Closing of $5.5 Million Underwritten Public Offering of Common Stock

BootyEater69 Dec. 4 at 4:22 PM

$APRE trash

0 · Reply

TezBunny Dec. 4 at 12:28 PM

$APRE I told you back in September, under a dollar 🤣 We can do better than that tho, let’s tear this sucker down

1 · Reply

NewsAndFilings Dec. 2 at 8:23 PM

$1 Stocks to Watch: $TOON $PRSO $APRE $PNPNF $PNPN.V December 2025 More Inside https://thestreetreports.com/1-stocks-to-watch-jspr-ftel-bynd-toon-december-2025-more-inside/

0 · Reply

FloFloFloFlo Dec. 2 at 6:23 PM

$APRE what’s going on at this company? What are they actually doing day to day?

0 · Reply

topstockalerts Nov. 24 at 1:57 PM

Pre Market Top Gainers PT2 $GELS $BRLS $APRE $CHSN $VSA

0 · Reply

Bulltrader988 Nov. 18 at 7:55 PM

$APRE 13 G filled yesterday: LYTTON LAURENCE W 681,837 shares = 9.9 % ownership 👃👀 https://www.sec.gov/Archives/edgar/data/1105806/000093583625000708/xslSCHEDULE_13G_X01/primary_doc.xml

1 · Reply

NewsAndFilings Nov. 17 at 8:32 PM

$APRE 3Q25 Review & Outlook: Synthetic Lethality Programs Around The WEE1i and ATRi Continue to Progress https://thestreetreports.com/wp-content/uploads/2025/11/APRE-Report.pdf

0 · Reply

MsGrumpy Nov. 17 at 5:11 PM

$APRE Maxim Group: Issued A Buy Rating ($10 Price Target) Aprea Therapeutics https://thestreetreports.com/wp-content/uploads/2025/11/APRE-Report.pdf

1 · Reply

NewsAndFilings Nov. 13 at 12:37 PM

Yesterday's Recap: $APRE Q3 Financials $CBDL Secures Major Hemp Flower Order $KRTL Publishes Investor Presentation $KARX and Hockey Canada Partnership

0 · Reply

d_risk Nov. 12 at 4:30 PM

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MsGrumpy Nov. 12 at 2:40 PM

$APRE Aprea Therapeutics Clinical Progress: Reported along with 3Q https://www.globenewswire.com/news-release/2025/11/12/3186275/0/en/Aprea-Therapeutics-Reports-Third-quarter-2025-Financial-Results-and-Provides-a-Clinical-Update.html

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Giants67 Nov. 12 at 1:59 PM

$APRE Aprea Therapeutics Reports Third quarter 2025 Financial Results and Provides a Clinical Update https://www.globenewswire.com/news-release/2025/11/12/3186275/0/en/Aprea-Therapeutics-Reports-Third-quarter-2025-Financial-Results-and-Provides-a-Clinical-Update.html

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Bulltrader988 Nov. 12 at 1:52 PM

$APRE 👃👀 https://www.stocktitan.net/news/APRE/aprea-therapeutics-reports-third-quarter-2025-financial-results-and-wppb94fqbath.html

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NewsAndFilings Nov. 12 at 1:47 PM

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Love_To_Learn Nov. 10 at 1:15 PM

$SBEV using your 1.09* side note $APRE (A) KBA (P)STV (R) $BRTX (E) $POET using code ET from poet for world events space *THeme*

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Bdtmandate Nov. 10 at 7:10 AM

$APRE Been waiting for 5 months… And all it does it keep going down… Guess imma just take the loss here

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FloFloFloFlo Nov. 6 at 8:18 PM

$APRE any other disappointed bag holders in here?

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NewsAndFilings Nov. 3 at 8:28 PM

$APRE Aprea Therapeutics (Nasdaq: APRE) Transforms Cutting-Edge Science into Next-Generation Cancer Therapies – More Stocks Inside https://thestreetreports.com/aprea-therapeutics-nasdaq-apre-transforms-cutting-edge-science-into-next-generation-cancer-therapies-more-stocks-inside/

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Jtree123 Oct. 28 at 2:28 PM

$APRE $SIGL $SNYR $SPTY $TOON

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Bulltrader988 Oct. 25 at 8:17 PM

$APRE 👃👀 https://finviz.com/quote.ashx?t=APRE&ty=c&ta=1&p=d

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NewsAndFilings Oct. 25 at 2:28 PM

Weekly Rundown: $APRE Clinical Update $SNYR FOCUSfactor® Expansion $TOON $7.3 Million Financing $SIGL Major Encryption Milestone $SPTY Appoints Robert Fedder as CEO

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Bulltrader988 Oct. 24 at 2:36 PM

$APRE 👃👀 https://www.stocktitan.net/news/APRE/aprea-therapeutics-provides-clinical-update-from-acesot-1051-trial-zv04tgf74l20.html

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Market Cap	6.44M
Revenue (ttm)	1.50M
Net Income (ttm)	-12.96M
EPS (ttm)	N/A
PE Ratio	0.00
Forward PE	N/A
Profit Margin	-864.00%
Debt to Equity Ratio	0.00

Volume	88,300
Avg Vol	96,052
Day's Range	N/A - N/A
Shares Out	6.31M
Stochastic %K	21%
Beta	1.23
Analysts	Strong Sell
Price Target	$13.67