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Market Cap 659.53M P/E - EPS this Y -159.40% Ern Qtrly Grth -
Income -32.18M Forward P/E -7.95 EPS next Y -13.90% 50D Avg Chg 24.00%
Sales 58.88M PEG - EPS past 5Y - 200D Avg Chg 67.00%
Dividend N/A Price/Book 3.87 EPS next 5Y - 52W High Chg -
Recommedations 2.40 Quick Ratio 7.82 Shares Outstanding 65.56M 52W Low Chg 185.00%
Insider Own 4.65% ROA -8.30% Shares Float 44.94M Beta 1.17
Inst Own 91.10% ROE -12.69% Shares Shorted/Prior 4.74M/5.61M Price 13.75
Gross Margin -37.41% Profit Margin -54.66% Avg. Volume 216,427 Target Price 61.50
Oper. Margin 5.01% Earnings Date May 9 Volume 182,773 Change 3.62%
About Alpine Immune Sciences, Inc.

Alpine Immune Sciences, Inc. operates as a clinical-stage biopharmaceutical company. It focuses on the discovery and development of immunotherapies through protein engineering technologies for treating autoimmune and inflammatory diseases. The company's product pipeline includes Povetacicept, a dual B cell cytokine antagonist, which is in Phase 2 clinical trial for the treatment of multiple autoimmune and inflammatory diseases; and Acazicolcept, a dual inhibitor of the CD28 and ICOS T cell costimulatory pathways that is in preclinical trial for the treatment of systemic lupus erythematosus. It is also developing RUBY-3 that has completed Phase 1 clinical trial for the treatment of glomerulonephritis; and RUBY-4, which has completed Phase 1 clinical trial for the treatment of cytopenias. The company was incorporated in 2007 and is headquartered in Seattle, Washington.

Alpine Immune Sciences, Inc. News
04/18/24 Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?
04/15/24 Can You Afford to Ignore These 3 Biotech Stocks Up Over 160% in 2024?
04/15/24 Here's (at Least) 1 new Reason to Buy Vertex Pharmaceuticals Stock
04/13/24 Could This Stock Be the Next Biotech Buyout?
04/12/24 Alpine (ALPN) Surges 37% on $4.9B Buyout Offer From Vertex
04/12/24 Health Care Roundup: Market Talk
04/11/24 These Stocks Moved the Most Today: CarMax, Apple, Fastenal, Rivian, Alpine Immune, Nike, Robinhood, Constellation Brands, and More
04/11/24 Vertex Pharmaceuticals to buy Alpine Immune Sciences in $4.9B deal
04/11/24 Alpine Catapults 37% After Vertex Pledges $4.9 Billion To Buy It
04/11/24 Stocks to Watch Thursday: Robinhood, Alpine Immune, Constellation Brands
04/11/24 Vertex Pharmaceuticals Seeks a Second Act With Alpine Immune Deal. What Wall Street Says.
04/11/24 The $5 BILLION Reason Alpine Immune Sciences (ALPN) Stock Is Up 30% Today
04/11/24 These Stocks Are Moving the Most Today
04/11/24 Vertex to Pay $4.9 Billion for Kidney Disease Drug Developer
04/10/24 Vertex Pharmaceuticals to Acquire Alpine Immune Sciences for $4.9 Billion
04/10/24 Vertex Pharma bets on kidney disease treatment with $4.9 billion Alpine Immune deal
04/10/24 UPDATE 3-Vertex Pharma bets on kidney disease treatment with $4.9 bln Alpine Immune deal
04/10/24 Alpine Immune Sciences Shares Updated Clinical Data from Povetacicept in IgA Nephropathy
04/10/24 Vertex Enters Into Agreement to Acquire Alpine Immune Sciences
04/10/24 Vertex to buy kidney disease drugmaker Alpine for $4.9B
ALPN Chatroom

User Image NinjaXLightning Posted - 1 day ago

$HCP For recent reference, $ALPN accepted a $65 per share cash buyout from $VRTX a couple of weeks ago and has been trading at about $64.50 per share. Should see this trading over $34.

User Image Aigner_Andreas Posted - 2 days ago

#TrendFollowing #TOP10 WK 17 BUY US $VST $AYX $NRG $ALPN $CAT RSG SLM WAB AXP SFM

User Image intratio Posted - 2 days ago

$ALPN https://www.intratio.com/stock-forecast/ALPN The predictive algorithm is predicting that this stock s price will quickly deteriorate in the near future and has a dramatic negative long-term outlook

User Image DiorCapital Posted - 6 days ago

$ALPN BIG BIG BIG GREEN CANDLE

User Image hospitalphysician Posted - 1 week ago

@biotechdollars Personally, I feel a little ripped off on $ALPN. The price was a little low. Are you looking at anything else right now?. It is a tough market. I’m 80% cash, 10% long (9% is in one company) , and 10% short

User Image krayzk4 Posted - 1 week ago

$ALPN if market has a big correction does this fall with it?

User Image Aigner_Andreas Posted - 1 week ago

#TrendFollowing #TOP10 WK 16 BUY US $VST $EME $ALPN $NRG $WAB HIG SPOT TRV CAT THC

User Image Blue_pineslapel Posted - 1 week ago

$ALPN why do I see big short coming🧐

User Image RonIsWrong Posted - 1 week ago

$ALPN $XBI $MRUS $SWTX $FUSN FUSN ☑️ ALPN ☑️ SNDX _?_ SWTX - bring it !! KRYS _?_

User Image Robbullishious Posted - 1 week ago

$VKTX the Effin market is relapsing the past few weeks.. MMs and retail taking profits.. It will re-correct itself soon.. Even $ALPN down after the 1st day back on the market after being bought out! That ought to tell you something is squirrelly with the market! On that note, ALPN is sitting where it needs to be at its current PP. however VKTX on the other hand is way to cheap for having the Best In Class Oral (Glp1/GIP) weight loss & top notch NASH/MASH upcoming drugs! We longs know what we have. The only thing holding the current PP down is the MM / bots as well as 18-24 months to FDA approval!

User Image hospitalphysician Posted - 1 week ago

@LongInvestor2 Agreed. On the data alone, I think the stock could have hit $70. $ALPN was a big win for me, but I felt shortchanged.

User Image AlertsAndNews Posted - 1 week ago

And that's a wrap for the week! Stellar plays on $PXMD $RLYB $ALPN $CADL $MGRM to name a few. Signing off on another productive week! Link in bio for more! All trading/investing involves a risk of loss. Do your own due diligence always!

User Image knows_nothing Posted - 1 week ago

$ALPN is this call option a dud? Breakeven is 65.20 and exp is 11/15. But I don’t understand with the acquired news?

User Image Capitulation_0 Posted - 1 week ago

$CYTK has 13.3% shorts.. that's 13.2m shares, rather high I'd say on the verge of a $13+B Buyout. $ALPN had 11.2% shorts. $CYTK shorts about to join $ALPN shorts on that pain ride.

User Image erevnon Posted - 1 week ago

Leerink Partners downgrades Alpine Immune Sciences $ALPN from Outperform to Market Perform and raises the price target from $42 to https://marketsblock.com/stock-upgrades-and-downgrades/

User Image FE123 Posted - 1 week ago

$JANX $ALPN Buyout offer can come on any Monday for $IOVA now that we are FDA Approved for Melanoma! $IOVA

User Image Sakthi87 Posted - 1 week ago

$ALPN so what happens to the calls and puts booked on this stock? Looks like the price is going to stay the same per the below. “Alpine Immune Sciences, Inc. has agreed to be acquired by Vertex Pharmaceuticals Incorporated. Under the proposed transaction, Alpine shareholders will receive $65.00 per share.”

User Image TheDayTradingAcademy Posted - 1 week ago

Alpine Immune Sciences shares based in Seattle, skyrocketed +36.90% on Thursday at $64.40, after Vertex Pharmaceuticals agreed to buy the biotech firm for $4.9B in cash. The deal values Alpine shares at $65, roughly 67% above its close on Tuesday, the day before reports that $ALPN was considering its options. Alpine stock is up +237.88% in 2024 & +780.98% y/y, with a market cap of $4.22B.

User Image cholle Posted - 2 weeks ago

$ALPN +49.19%

User Image Sakthi87 Posted - 2 weeks ago

$ALPN can someone please explain what will happen to calls and puts booked today on this stock? Looks like this stocks price is not going to move either way.

User Image Iglorious18 Posted - 2 weeks ago

$IPA i feel like a hedge fund with just 4 shares moved the price up by 7.30% $ALPN

User Image BioRich Posted - 2 weeks ago

$MLTX bought the news. This is a big deal and future is definitely north of 100$. My Scwab account shows $47.99 already. We may have a runner. Bios and BOs are hot right now. $ALPN $MRNA and $PFE bring that money over here for a nice 2x.

User Image jitendermahajan Posted - 2 weeks ago

$ALPN so what happens next ? since they agreed to offer do I sell and move on ?

User Image patatechaude Posted - 2 weeks ago

@Machman1 Tell that to the $ALPN long term holders. You hold and then it happens. $CAPR turn is coming.

User Image CycleTrade Posted - 2 weeks ago

$ALPN oh boy

User Image Alphasearch Posted - 2 weeks ago

$ALPN Congrats. Had this on my watch for months after showing up on a volume scan. Didn't pull the trigger due to it being a biotech, but should have given the last ER.

User Image kokooo Posted - 2 weeks ago

$ALPN RIGL=3 approved drugs 120 million in revenue =and huge contract with LLY .good luck and stay safe.

User Image Finnisher2M Posted - 2 weeks ago

$RLYB $ELYM $ALPN $RENT 👈👑 Crazy run

User Image kokooo Posted - 2 weeks ago

$ALPN i believe they will pay around 1.5 to 2 billion for RIGL

User Image kokooo Posted - 2 weeks ago

$ALPN for who asked me why i think lly will buy RIGL Lilly will pay an upfront cash payment to Rigel of $125 million. Rigel may also be eligible to receive up to $835 million in potential development, regulatory, and commercial milestone payments, as well as tiered royalties ranging from the mid-single digit to high-teens that will vary depending upon Rigel's clinical development investment. Lilly and Rigel will co-develop R552 at specified contribution levels. Lilly will be responsible for all costs of global commercialization for R552, and Rigel will have the right to co-commercialize R552 in the U.S. Lilly will be solely responsible for all clinical development and commercialization of brain penetrating RIPK1 inhibitors in CNS indications.

Analyst Ratings
TD Cowen Hold Apr 16, 24
Leerink Partners Market Perform Apr 12, 24
Wedbush Neutral Apr 11, 24
Wolfe Research Peer Perform Apr 11, 24
RBC Capital Sector Perform Apr 11, 24
Morgan Stanley Equal-Weight Apr 11, 24
Guggenheim Buy Apr 9, 24
HC Wainwright & Co. Buy Mar 21, 24
Morgan Stanley Overweight Mar 19, 24
Insider Trades Relationship Date Transactions Cost($) #Shares Value($) #Share Own SEC Form 4
Rickey James Paul See Remarks See Remarks Jan 25 Sell 23.1 118,000 2,725,800 01/29/24
Rickey James Paul See Remarks See Remarks Jan 25 Option 8.11 118,000 956,980 44,000 01/29/24
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 28 Sell 20.04 1,016 20,361 12/29/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 28 Option 6.7 75,457 505,562 2,675,421 12/29/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 22 Sell 20.23 91,884 1,858,813 12/27/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 22 Option 0.55 91,884 50,536 29,573 12/27/23
Rickey James Paul See Remarks See Remarks Dec 19 Sell 19.21 15,213 292,242 12/21/23
Rickey James Paul See Remarks See Remarks Dec 19 Option 5.02 15,213 76,369 15,213 12/21/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 19 Sell 20.01 2,402 48,064 12/21/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 19 Option 0.45 2,402 1,081 2,402 12/21/23
Rickey James Paul See Remarks See Remarks Dec 14 Option 5.02 58,787 295,111 1,800 12/18/23
Rickey James Paul See Remarks See Remarks Dec 14 Sell 19.03 58,787 1,118,717 12/18/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 08 Sell 17.24 118,000 2,034,320 12/12/23
GOLD MITCHELL Executive Chairman a.. Executive Chairman and CEO Dec 08 Option 0.45 8,613 3,876 8,613 12/12/23
Rickey James Paul See Remarks See Remarks Dec 04 Sell 16.05 70,811 1,136,517 12/06/23
Rickey James Paul See Remarks See Remarks Dec 04 Option 3.23 70,811 228,720 6,446 12/06/23
Rickey James Paul See Remarks See Remarks Nov 30 Sell 16 700 11,200 12/01/23
Rickey James Paul See Remarks See Remarks Nov 30 Option 3.23 700 2,261 700 12/01/23
Rickey James Paul See Remarks See Remarks Nov 06 Sell 16.03 18,003 288,588 11/08/23
Rickey James Paul See Remarks See Remarks Nov 06 Option 3.23 10,989 35,494 18,003 11/08/23
Venkatesan Jay Director Director Jul 15 Option 0.45 20,063 9,028 238,126 07/19/22
Frazier Life Sciences VIII, L.... 10% Owner 10% Owner Feb 11 Buy 7.1006 112,665 799,989 1,484,115 02/15/22