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Market Cap 92.31B P/E 28.51 EPS this Y 10.10% Ern Qtrly Grth 18.30%
Income 3.62B Forward P/E 22.18 EPS next Y 8.60% 50D Avg Chg 4.00%
Sales 9.87B PEG 1.83 EPS past 5Y 29.84% 200D Avg Chg 12.00%
Dividend N/A Price/Book 5.97 EPS next 5Y 12.80% 52W High Chg -2.00%
Recommedations 2.20 Quick Ratio 3.60 Shares Outstanding 258.46M 52W Low Chg 32.00%
Insider Own 0.11% ROA 13.17% Shares Float 257.56M Beta 0.37
Inst Own 97.27% ROE 22.99% Shares Shorted/Prior 3.98M/4.05M Price 358.40
Gross Margin 55.16% Profit Margin 36.68% Avg. Volume 1,274,488 Target Price 466.14
Oper. Margin 37.97% Earnings Date May 6 Volume 2,166,599 Change 3.07%
About Vertex Pharmaceuticals Incorpor

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Vertex Pharmaceuticals Incorpor News
04/18/24 Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?
04/18/24 Vertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic Pain
04/18/24 Vertex begins bid for US approval of non-opioid painkiller
04/16/24 Vertex Pharmaceuticals (VRTX) Stock Falls Amid Market Uptick: What Investors Need to Know
04/15/24 Vertex Pharma scientist talks about the long road to developing non-addictive painkillers
04/15/24 Here's (at Least) 1 new Reason to Buy Vertex Pharmaceuticals Stock
04/15/24 Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
04/13/24 3 Magnificent Stocks That Could Double or More by 2030
04/13/24 Could This Stock Be the Next Biotech Buyout?
04/12/24 Alpine (ALPN) Surges 37% on $4.9B Buyout Offer From Vertex
04/12/24 Health Care Roundup: Market Talk
04/11/24 Vertex Pharmaceuticals to buy Alpine Immune Sciences in $4.9B deal
04/11/24 Alpine Catapults 37% After Vertex Pledges $4.9 Billion To Buy It
04/11/24 Stocks to Watch Thursday: Robinhood, Alpine Immune, Constellation Brands
04/11/24 Vertex Pharmaceuticals Seeks a Second Act With Alpine Immune Deal. What Wall Street Says.
04/11/24 Dow Jones Lower Despite PPI Inflation Relief; Nvidia, Microsoft Price Targets Raised
04/11/24 The $5 BILLION Reason Alpine Immune Sciences (ALPN) Stock Is Up 30% Today
04/11/24 These Stocks Are Moving the Most Today
04/11/24 Vertex to Pay $4.9 Billion for Kidney Disease Drug Developer
04/11/24 Vertex Pharmaceuticals: Buy, Sell, or Hold?
VRTX Chatroom

User Image themarker Posted - 1 hour ago

Cathie Wood and Ark Invest's trade activity from 2024/04/18 $STNE $TWLO $VRTX

User Image kamenrider888 Posted - 5 hours ago

$VRTX not worth more than $280..still even under $400 now is still overvalued like Purdue was as they try to sweep all the patient serious bad side effects under their bankers and analysts rugs...reminds me of early days MBOT. Vertex products are being very overrated.

User Image ElijahJobs Posted - 9 hours ago

$VRTX Accumulating shares whenever it dips below 400. Very nice bargains, indeed. Next year when non-addictive pain killer gets approved, will see this in the 600’s. JMO

User Image BosFreedom Posted - 12 hours ago

$VRTX will they have any crispr sales for Q1?

User Image Real_Men_of_Genius Posted - 15 hours ago

$VRTX is one of the best large biotechs, perhaps the top company, if their pain med can get approved and not end up like $NKTR

User Image cambob Posted - 16 hours ago

$VRTX Historically high ROIC and significant increase in invested capital this past year. Pharma is a slow industry so the returns on the newly invested capital probably won’t be realized immediately but I have faith that this is a top quality healthcare company and capital allocator.

User Image TradingUK Posted - 16 hours ago

$DFLI $INDO $HUSA $VRTX $HNRA ENERGY BACK ON THE RISE = BUY 🚨

User Image DonCorleone77 Posted - 18 hours ago

$VRTX Vertex Pharmaceuticals announces advancements in suzetrigine pain program Vertex Pharmaceuticals announced important advancements across its suzetrigine pain program, which has the potential to be the first new class of medicine for acute and neuropathic pain in more than two decades. Suzetrigine is an oral selective NaV1.8 pain signal inhibitor. Following the positive Phase 3 results in acute pain announced in January, the FDA has granted a rolling New Drug Application (NDA) submission for suzetrigine in moderate-to-severe acute pain. Vertex has started the rolling submission process and is on track to complete the submission in the second quarter of 2024. Suzetrigine was previously granted FDA Fast Track and Breakthrough Therapy designations in moderate-to-severe acute pain. In neuropathic pain, Vertex released positive results from its Phase 2 study in December 2023 and recently completed a successful end-of-phase 2 meeting with the FDA. Vertex is now preparing to initiate a Phase 3 pivotal program of suzetrigine in patients with DPN in 2H 2024. In addition, the FDA recently granted suzetrigine Breakthrough Therapy designation for the treatment of pain associated with DPN. The Phase 3 program will include two identical 12-week randomized, double-blind, placebo-controlled studies evaluating the efficacy and safety of suzetrigine in patients with DPN. The primary endpoint for both studies will be the change from baseline in weekly average of daily pain intensity on the numeric pain rating scale, or NPRS, assessed at Week 12 compared to placebo. Both studies will also include a key secondary endpoint of change from baseline in the weekly average of daily pain intensity on the NPRS at Week 12 compared to pregabalin. Approximately 1,100 patients are expected to enroll in each Phase 3 study. After completing participation in the randomized controlled studies, patients may roll over into an open-label study to evaluate the long-term safety and effectiveness of suzetrigine in DPN. Additionally, Vertex continues to enroll its Phase 2 study of suzetrigine in patients with lumbosacral radiculopathy, or LSR, which is pain caused by impairment or injury to nerve roots in the area of the lumbar spine. The company is on track to complete enrollment in the Phase 2 LSR study by the end of the year.

User Image kagrawala Posted - 18 hours ago

$VRTX nice news on VX-548 today. https://news.vrtx.com/news-releases/news-release-details/vertex-announces-advancements-suzetrigine-vx-548-acute-and

User Image Stock_Titan Posted - 19 hours ago

$VRTX Vertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic Pain https://www.stocktitan.net/news/VRTX/vertex-announces-advancements-of-suzetrigine-vx-548-in-acute-and-bl8k4guie2x1.html

User Image Thestocktraderhubzee Posted - 19 hours ago

$VRTX Guggenheim Maintains Buy on Vertex Pharmaceuticals, Raises Price Target to $450

User Image Rubiks_KubeMD Posted - 1 day ago

$VRTX when this breaks north of about 425 on the way back up punch your tickets... No idea exactly when but before eoy an epic run is in the cards.

User Image Rubiks_KubeMD Posted - 1 day ago

$VRTX wow... It's going to head even deeper into oversold territory here 👀 Long term am super bullish but in the short term yikes... 😬

User Image stubbybrown Posted - 1 day ago

$VRTX very close to oversold territory. Will consider adding if the 24hr RSI drops below 30 down to 25.

User Image kamenrider888 Posted - 2 days ago

$VRTX still too overvalued

User Image JFDI Posted - 3 days ago

$VRTX back thru 400

User Image kamenrider888 Posted - 4 days ago

$VRTX as predicted..below $400 already lol

User Image cuttail07 Posted - 5 days ago

$VRTX Regarding the Alpine acquisition: Reshma is a board certified nephrologist. Her excitement about the prospects for Povetacicept in various nephropathies (most notably IgAN at this time) was palpable on the conference call. I trust her on this one. But I’m putting this on the back burner for the next 18-24 months. What I really want to hear about is a strong focus on Vanza triple and VX-548 approvals and launches. These will be the main revenue adds to the company over the next 2 years.

User Image Timefortendies77 Posted - 5 days ago

$VRTX Once we get a PDUFA data for the pain drug, and that date gets closer the party will begin again--until then not worth the investment.

User Image cuttail07 Posted - 6 days ago

$VRTX 15% increase in my position today.

User Image GreenGoblin_ Posted - 6 days ago

@BioRunner9 wrong stock $VRTX

User Image russellkbrett Posted - 6 days ago

$EDIT What a walk down! Market cap getting closer to the $427M they have just in cash & cash equivalents. 6-straight weeks down -46% off post Q4 ER high where they beat estimates for the 3rd consecutive quarter narrowing EPS loss to -$0.23 from -$0.55 prev and blew out the revenue estimates ($60M vs $3.70M est) due to $VRTX licensing deal. Short interest has grown to more than 20% of float now (over 16M shares). Last time SI was this high, it preceded a big multiweek rally. We'll see. Holding on here..

User Image blueb22 Posted - 6 days ago

$BLUE $vrtx $crsp - CMS CGT Access model (SCD Gene therapies at this time) home page (Looks like they are continuing to update this with milestone reached and many links and all that -- good to bookmark this page for easy reference) for those invested in SCD Gene therapies (Lyfgenia and Casgevy) https://www.cms.gov/priorities/innovation/innovation-models/cgt

User Image UncleStock Posted - 1 week ago

$FANG $VRTX $MNST $META suggested for $NDX US NASDAQ 100 - value screen: https://zpr.io/tk2Y7

User Image SemisbullWatermelon Posted - 1 week ago

$VRTX any body has any idea why VRTX down so much recently?

User Image svertical1 Posted - 1 week ago

$CRSP $VRTX No small benefit for VRTX success as well.

User Image svertical1 Posted - 1 week ago

$CRSP $VRTX Important for VRTX results as well!

User Image DoctrBenway Posted - 1 week ago

$BLUE $CRSP $VRTX https://endpts.com/cms-to-increase-reimbursement-for-new-sickle-cell-gene-therapies/

User Image ProKnifeCatcher87 Posted - 1 week ago

$REGN politicians are crooked Shame Shame Shame on them This is a life saving game changing company Thankyou for the dip !!! Added $235k to 401 today $VRTX $AMGN

User Image theflynews Posted - 1 week ago

Analyst thinks this drugmaker could be next after Alpine's $4.9B acquisition - $VRTX - https://thefly.com/permalinks/entry.php/VRTXid389582

Analyst Ratings
Guggenheim Buy Apr 18, 24
UBS Buy Apr 17, 24
Oppenheimer Outperform Apr 15, 24
Canaccord Genuity Sell Apr 12, 24
HC Wainwright & Co. Buy Apr 11, 24
Evercore ISI Group Outperform Apr 11, 24
Cantor Fitzgerald Overweight Feb 20, 24
Wolfe Research Outperform Feb 15, 24
Cantor Fitzgerald Overweight Feb 6, 24
Insider Trades Relationship Date Transactions Cost($) #Shares Value($) #Share Own SEC Form 4
Bozic Carmen EVP and CMO EVP and CMO Oct 03 Sell 345.28 5,651 1,951,177 46,254 10/05/23
Ambrose Kristen SVP & Chief Accounti.. SVP & Chief Accounting Officer May 30 Sell 329.82 289 95,318 6,838 06/01/23
Tatsis Ourania EVP, Chief Reg. & Qu.. EVP, Chief Reg. & Quality Off. Feb 24 Sell 288.27 354 102,048 56,805 02/28/23
Arbuckle Stuart A EVP, COO EVP, COO Feb 24 Sell 287.89 5,034 1,449,238 56,556 02/28/23
Ambrose Kristen SVP & Chief Accounti.. SVP & Chief Accounting Officer Feb 24 Sell 288.52 1,207 348,244 7,303 02/28/23
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Feb 24 Sell 288.52 4,238 1,222,748 32,038 02/28/23
Arbuckle Stuart A EVP, COO EVP, COO Feb 22 Sell 294.14 2,401 706,230 66,304 02/24/23
Arbuckle Stuart A EVP, COO EVP, COO Feb 17 Sell 293.03 2,402 703,858 68,705 02/22/23
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Feb 17 Sell 293.13 4,002 1,173,106 40,246 02/22/23
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Feb 06 Sell 304.48 1,304 397,042 68,645 02/08/23
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Feb 06 Option 187.53 1,304 244,539 69,949 02/08/23
Kewalramani Reshma CEO & President CEO & President Jan 25 Sell 315.05 10,000 3,150,500 89,598 01/27/23
Lee Yuchun Director Director Jan 17 Sell 312.1 4,442 1,386,348 1,875 01/19/23
Lee Yuchun Director Director Jan 17 Option 72.14 4,442 320,446 2,317 01/19/23
Sanna Bastiano EVP, Cell & Genetic.. EVP, Cell & Genetic Therapies Oct 18 Sell 300.93 1,791 538,966 39,192 10/20/22
Kewalramani Reshma CEO & President CEO & President Aug 15 Sell 305.06 11,689 3,565,846 99,598 08/17/22
Arbuckle Stuart A EVP, COO EVP, COO Aug 15 Option 155.57 6,571 1,022,250 67,451 08/17/22
Arbuckle Stuart A EVP, COO EVP, COO Aug 15 Sell 303.05 22,173 6,719,528 45,278 08/17/22
Liu Joy SVP, General Counsel SVP, General Counsel Aug 15 Sell 303.14 3,747 1,135,866 9,605 08/17/22
Bhatia Sangeeta N. Director Director Aug 08 Sell 292.97 621 181,934 4,661 08/10/22
Liu Joy SVP, General Counsel SVP, General Counsel Aug 09 Sell 300.00 946 283,800 13,388 08/10/22
Tatsis Ourania EVP, Chief Reg. & Qu.. EVP, Chief Reg. & Quality Off. Aug 09 Sell 299.68 1,400 419,552 46,090 08/10/22
Arbuckle Stuart A EVP, COO EVP, COO Aug 09 Option 155.57 1,926 299,628 66,686 08/10/22
Arbuckle Stuart A EVP, COO EVP, COO Aug 09 Sell 300.98 5,690 1,712,576 60,996 08/10/22
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Aug 08 Sell 292.8 1,304 381,811 36,077 08/10/22
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Aug 08 Option 187.53 1,304 244,539 37,381 08/10/22
Bhatia Sangeeta N. Director Director Jul 29 Sell 279.58 621 173,619 5,282 08/02/22
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Jul 19 Option 171.55 17,765 3,047,586 53,942 07/21/22
ALTSHULER DAVID EVP, Global Research.. EVP, Global Research and CSO Jul 19 Sell 288.18 17,865 5,148,336 36,077 07/21/22
Arbuckle Stuart A EVP, COO EVP, COO May 02 Sell 263.98 306 80,778 64,760 05/04/22
Sanna Bastiano EVP, Cell & Genetic.. EVP, Cell & Genetic Therapies May 02 Sell 259.66 320 83,091 41,696 05/04/22
Bhatia Sangeeta N. Director Director May 02 Sell 259.81 737 191,480 5,903 05/04/22
WAGNER CHARLES F JR EVP & Chief Financia.. EVP & Chief Financial Officer May 02 Sell 259.61 343 89,046 42,730 05/04/22
Lee Yuchun Director Director Apr 18 Option 81.54 2,000 163,080 3,875 04/20/22
Lee Yuchun Director Director Apr 18 Sell 284.68 2,000 569,360 1,875 04/20/22
Lee Yuchun Director Director Apr 14 Option 81.54 2,000 163,080 3,875 04/18/22
Lee Yuchun Director Director Apr 14 Sell 289.45 2,000 578,900 1,875 04/18/22
LEIDEN JEFFREY M Executive Chairman Executive Chairman Apr 13 Sell 289.04 15,789 4,563,653 74,160 04/14/22
Lee Yuchun Director Director Apr 12 Option 81.54 4,000 326,160 3,875 04/14/22
Lee Yuchun Director Director Apr 12 Sell 284.86 4,000 1,139,440 1,875 04/14/22
Lee Yuchun Director Director Apr 08 Option 81.54 4,000 326,160 3,875 04/12/22
Lee Yuchun Director Director Apr 08 Sell 279.38 4,000 1,117,520 1,875 04/12/22
Bhatia Sangeeta N. Director Director Apr 08 Option 125.71 1,907 239,729 7,098 04/12/22
Bhatia Sangeeta N. Director Director Apr 08 Sell 280.2 1,907 534,341 5,191 04/12/22
MCGLYNN MARGARET G Director Director Apr 08 Option 127.54 5,000 637,700 6,099 04/12/22
MCGLYNN MARGARET G Director Director Apr 08 Sell 280.84 5,000 1,404,200 1,099 04/12/22
Lee Yuchun Director Director Apr 06 Option 81.54 4,000 326,160 3,875 04/08/22
Lee Yuchun Director Director Apr 06 Sell 273.12 4,000 1,092,480 1,875 04/08/22
Sanna Bastiano EVP, Cell & Genetic.. EVP, Cell & Genetic Therapies Apr 07 Sell 276.37 561 155,044 42,782 04/08/22
Sanna Bastiano EVP, Cell & Genetic.. EVP, Cell & Genetic Therapies Apr 04 Sell 270.25 3,725 1,006,681 43,343 04/06/22