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Market Cap 80.70M P/E - EPS this Y 58.50% Ern Qtrly Grth -
Income -10.08M Forward P/E -1.85 EPS next Y 5.90% 50D Avg Chg -3.00%
Sales 54.23M PEG -0.07 EPS past 5Y - 200D Avg Chg -10.00%
Dividend N/A Price/Book 1.24 EPS next 5Y 36.90% 52W High Chg -52.00%
Recommedations 2.20 Quick Ratio 4.61 Shares Outstanding 52.72M 52W Low Chg 116.00%
Insider Own 18.94% ROA -10.19% Shares Float 36.87M Beta 0.89
Inst Own 27.24% ROE -22.24% Shares Shorted/Prior 1.14M/1.17M Price 1.54
Gross Margin 24.51% Profit Margin -18.59% Avg. Volume 312,087 Target Price 6.67
Oper. Margin -24.42% Earnings Date Nov 13 Volume 258,744 Change 0.99%
About Spero Therapeutics, Inc.

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adults; SPR206, a direct acting IV-administered agent to treat MDR Gram-negative bacterial infections in the hospital; and SPR720, a novel oral antibiotic for the treatment of non-tuberculous mycobacterial pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; license agreement with Everest Medicines to develop, manufacture, and commercialize SPR206 in China, South Korea, and Southeast Asian countries; collaboration agreement with Bill & Melinda Gates Medical Research Institute to develop SPR720 for the treatment of lung infections caused by Mycobacterium tuberculosis; and license agreement with Vertex Pharmaceuticals Incorporated for patents relating to SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Spero Therapeutics, Inc. News
09/20/23 Spero Therapeutics to Present at Cantor’s Global Healthcare 2023 Investor Conference
09/16/23 Insider Sell: Chief Medical Officer Kamal Hamed Sells 39,496 Shares of Spero Therapeutics Inc
09/12/23 Sensorium Therapeutics Appoints Veteran Life Sciences Executive Mr. David Southwell to its Board of Directors
09/06/23 Spero Therapeutics to Present at H.C. Wainwright 25th Annual Global Investment Conference
08/31/23 Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
08/29/23 Spero Therapeutics, Inc. (SPRO) Upgraded to Strong Buy: What Does It Mean for the Stock?
08/22/23 Down -11.72% in 4 Weeks, Here's Why Spero Therapeutics, Inc. (SPRO) Looks Ripe for a Turnaround
08/13/23 Spero Therapeutics, Inc. (NASDAQ:SPRO) Q2 2023 Earnings Call Transcript
08/11/23 Q2 2023 Spero Therapeutics Inc Earnings Call
08/10/23 Spero Therapeutics, Inc. (SPRO) Reports Q2 Loss, Tops Revenue Estimates
08/10/23 Spero Therapeutics Announces Second Quarter 2023 Operating Results and Provides a Business Update
08/03/23 Spero Therapeutics to Provide Business Update and Report Second Quarter 2023 Financial Results on Thursday, August 10, 2023
07/31/23 Spero Therapeutics Announces Special Protocol Assessment Agreement with FDA for Phase 3 PIVOT-PO Trial of Tebipenem HBr
07/05/23 Investors in Spero Therapeutics (NASDAQ:SPRO) have unfortunately lost 90% over the last three years
06/18/23 Strength Seen in TELA Bio, Inc. (TELA): Can Its 11.4% Jump Turn into More Strength?
06/14/23 Spero Therapeutics Appoints Sath Shukla as President & Chief Executive Officer
05/18/23 Time To Worry? Analysts Are Downgrading Their Spero Therapeutics, Inc. (NASDAQ:SPRO) Outlook
05/16/23 Spero Therapeutics, Inc. (NASDAQ:SPRO) Q1 2023 Earnings Call Transcript
05/12/23 Q1 2023 Spero Therapeutics Inc Earnings Call
05/11/23 Spero Therapeutics, Inc. (SPRO) Reports Q1 Loss, Tops Revenue Estimates
SPRO Chatroom

User Image Dr_My Posted - 2 hours ago

$SPRO Tebi better get approved by FDA this time around - my wife is a nurse practitioner and sees tons of UTI cases per week and many turn into complicated ones. The drug would be very beneficial. They need to get this thing fast track approved! Stock will soon be a penny stock if not!

User Image Caribbe Posted - 3 hours ago

$SPRO

User Image SPERO280 Posted - 5 hours ago

$SPRO you see that 2.00 above on the chart ? that is where she sits in CASH <<<<<<<<<<<<<<<<< and no pipe value on 3 drugs.....in mid/late stage. This is called overlooked and undervalued by Mr Market. BUT <<<< this is only if you are long term. Please sell to me better than gsk.

User Image SPERO280 Posted - 6 hours ago

$SPRO just give me 5 more days at gsk price..adding 50k

User Image NoGainer1 Posted - 2 days ago

$SPRO $ASMB $GLPG $CTMX dummies im no brainer club feiern mittlerweile die 38. verlustwoche in diesem jahr ;D

User Image Caribbe Posted - 2 days ago

$SPRO

User Image BabyMels Posted - 2 days ago

$SPRO Well this is fuckin ridiculous

User Image DummiesNixGerafft Posted - 3 days ago

Diversifikation ist alles. Depot YTD minus 20% $CTMX $GLPG $SPRO

User Image Dr_My Posted - 3 days ago

$SPRO what is the deal here? This will be in penny stock territory soon...

User Image NoGainer1 Posted - 3 days ago

$ASMB $CTMX $GLPG $SPRO gut was los im hauptchat von schrottdeals, jeder weiß bescheid, die zensur hat die arbeit auch eingestellt

User Image Dark_Sider_ Posted - 3 days ago

$SPRO what the F????

User Image SPERO280 Posted - 3 days ago

$SPRO Only questions remains will GSK add 2 pct 17.9 to 19.9 pct based on the max ownership at 1.20. one thing is for sure ...I am trying to get to 2 pct ....funds freeing up soon...to add the blood. Next year this time 3 p3s

User Image SPERO280 Posted - 3 days ago

$SPRO 2.05 cash /1.22 stock price /0 pipe val 3 mid late stage drugs ..targets 6-7 on disc sales est ...makes sense...

User Image SPERO280 Posted - 4 days ago

$SPRO Sitting on 52 week low like most small caps Yet meter is 100pct GREED ....LAUGHABLE......just LAUGHABLE .... Only question , can I add blocks less than GSK 17.9 pct BLOOD in the street.

User Image Caribbe Posted - 4 days ago

$SPRO

User Image mdboss Posted - 4 days ago

$SPRO Who really cares. I love the risk/reward. Why not sell the company to GSK for peanuts and I'll take contingency rewards when the pipeline products get approval. I've got lot's of skin in this game.

User Image Inc82 Posted - 4 days ago

$SPRO We’ll, it looks like they don’t want it to go below $1.20

User Image SPERO280 Posted - 4 days ago

$SPRO

User Image SPERO280 Posted - 4 days ago

$SPRO Just give me 9 more days at GSK price....Big Block coming.....I got time for TEBI 720 to become heros

User Image SPERO280 Posted - 4 days ago

$SPRO NOW the LOW becomes GSK .....we crossed the day.. Now in 1 year with all coming to fruition ...howabout re-test of the high 3.18 ......still only 160 mil .....Tebi and 720 will be in P3s .........no assignment val ......give me more at this level macro market ....love these indicators above ..what a joke

User Image BiotechJedi1728 Posted - 4 days ago

$SPRO Wow. This is insanely low again. SMH 🤦🏻‍♂️ the stock market is a joke. Should be above $2 no problem with Tebipenem trial and SPR206 trial starting soon. Each $1B drugs.

User Image SPERO280 Posted - 4 days ago

$SPRO Going to be interesting to see CANTOR target hopefully raising from i believe 6 to 7 ......for 25 ......MACRO MARKET IS DOMINATING INT RATES etc ...but that will change in time and really does not affect financially current NO BORROWING NEEDED NO DEBT . But in this climate Funds are not buying any bios ....LUMPING them all together ....THAT WILL CHANGE Buy BLOOD sell Euphoria

User Image cctranscripts Posted - 4 days ago

Spero Therapeutics to Present at Cantor’s Global Healthcare 2023 Investor Conference https://conferencecalltranscripts.com/summary/?id=523965&pr=true $SPRO

User Image Quantisnow Posted - 4 days ago

$SPRO 📰 Spero Therapeutics to Present at Cantor's Global Healthcare 2023 Investor Conference https://quantisnow.com/i/4980633?utm_source=stocktwits 45 seconds delayed.

User Image Stock_Titan Posted - 4 days ago

$SPRO Spero Therapeutics to Present at Cantor’s Global Healthcare 2023 Investor Conference https://www.stocktitan.net/news/SPRO/spero-therapeutics-to-present-at-cantor-s-global-healthcare-2023-dpv4f8gh03he.html

User Image SPERO280 Posted - 5 days ago

$SPRO I'd just like to get back to CASH LEVEL 2.00<< by MAR then 720 news take it over starting< to factor SOME value w/Tebi also ...Alot of News coming in the 4th qtr w/all 3 drugs. In a market like this in small cap ...Looks presently like another GAP SCENARIO rather than Walk up.

User Image Stockrocker77 Posted - 5 days ago

$SPRO a seller with huge amount of shares is done with selling. hopefully this will go up again. The Germans among us knows who the shark is. ;)

User Image BabyMels Posted - 5 days ago

$SPRO There, that's better. Sometimes the wheel gotta squeak to get a little grease.

User Image BabyMels Posted - 5 days ago

$SPRO Ok this is just nonsense

User Image NoGainer1 Posted - 5 days ago

$CTMX $SPRO goldener herbst ;D

Analyst Ratings
HC Wainwright & Co. Buy Sep 5, 23
HC Wainwright & Co. Buy Aug 14, 23
HC Wainwright & Co. Buy Aug 1, 23
HC Wainwright & Co. Buy Jul 20, 23
HC Wainwright & Co. Buy Apr 10, 23
HC Wainwright & Co. Buy Sep 26, 22
Evercore ISI Group Outperform Sep 23, 22
HC Wainwright & Co. Buy Aug 15, 22
HC Wainwright & Co. Buy May 23, 22
Insider Trades Relationship Date Transactions Cost($) #Shares Value($) #Share Own SEC Form 4
HAMED KAMAL Chief Medical Office.. Chief Medical Officer Sep 13 Sell 1.27 39,496 50,160 576,461 09/15/23
Keutzer Timothy Chief Operating Offi.. Chief Operating Officer Feb 01 Sell 1.86 3,394 6,313 327,144 02/03/23
JOSEPH TAMARA L Chief Legal Officer Chief Legal Officer Feb 01 Sell 1.86 3,394 6,313 324,644 02/03/23
Shukla Sath Chief Financial Offi.. Chief Financial Officer Feb 01 Sell 1.83 9,504 17,392 312,517 02/03/23
Shukla Sath Chief Financial Offi.. Chief Financial Officer Aug 29 Sell 0.8938 6,017 5,378 56,064 08/30/22
Aquilo Capital Management, LLC 10% Owner 10% Owner Feb 18 Buy 9.2419 14,828 137,039 5,162,963 02/23/22
Aquilo Capital Management, LLC 10% Owner 10% Owner Jan 31 Buy 11.5861 125,000 1,448,262 5,148,135 02/01/22
Aquilo Capital Management, LLC 10% Owner 10% Owner Jan 24 Buy 10.8931 1,599 17,418 5,023,135 01/26/22
Aquilo Capital Management, LLC 10% Owner 10% Owner Jan 18 Buy 12.4147 48,488 601,964 5,021,536 01/20/22
Aquilo Capital Management, LLC 10% Owner 10% Owner Jan 10 Buy 12.9253 8,867 114,609 4,973,048 01/12/22
Mahadevia Ankit CEO and President CEO and President Dec 27 Option 5.9 8,000 47,200 152,036 12/29/21
Mahadevia Ankit CEO and President CEO and President Dec 27 Sell 14.58 8,000 116,640 144,036 12/29/21
Aquilo Capital Management, LLC 10% Owner 10% Owner Sep 15 Buy 18.53 46,366 859,162 4,429,145 09/15/21
Aquilo Capital Management, LLC 10% Owner 10% Owner Aug 27 Buy 16.71 36,939 617,251 4,265,343 08/27/21
- - - Feb 04 Sell 19.05 100,000 1,905,000 3,832,209 02/04/21
- - - Dec 18 Sell 18.72 264,933 4,959,546 3,932,209 12/18/20
- - - Nov 06 Sell 14 174,100 2,437,400 4,323,042 11/06/20
Mahadevia Ankit CEO and President CEO and President Nov 05 Option 5.9 9,507 56,091 73,187 11/05/20
Mahadevia Ankit CEO and President CEO and President Nov 05 Sell 14.35 9,507 136,425 65,817 11/05/20
Mahadevia Ankit CEO and President CEO and President Oct 27 Option 5.9 20 118 65,837 10/27/20
Mahadevia Ankit CEO and President CEO and President Oct 27 Sell 14.25 20 285 65,817 10/27/20
Mahadevia Ankit CEO and President CEO and President Oct 15 Option 5.9 14,472 85,385 65,922 10/15/20
Mahadevia Ankit CEO and President CEO and President Oct 15 Sell 14.27 14,472 206,515 65,817 10/15/20
Mahadevia Ankit CEO and President CEO and President Sep 10 Sell 14.25 774 11,030 65,817 09/10/20
Mahadevia Ankit CEO and President CEO and President Sep 10 Option 5.9 774 4,567 66,591 09/10/20