microcapspeculator Posted - 1 day ago

$COYA As mentioned multiple times by management the ALS trial was waiting on alignment with the FDA that required additional preclinical data. We expect our activities in 2025 to be focused on the following indications: ALS (Amyotrophic Lateral Sclerosis) Program: We have alignment with the FDA on the data required to initiate our potentially pivotal COYA 302 Phase 2 double-blind randomized study in patients with ALS. We are targeting the submission of the requested data package by 2Q 2025 and initiation of the clinical trial upon FDA clearance. The roadmap to topline results is now clear with reduced uncertainty. In late 2023, we partnered with Dr. Reddy’s Laboratories, a multi-billion-dollar drug developer, to license COYA 302 in ALS in a deal that is worth up to $700 million. We still retain the rights to COYA 302 in ALS in Japan and South/Central America and Mexico, thus providing us direct upside and optionality in this indication alone.

Jwa68 Posted - 2 days ago

$COYA Just not sure what else you could ask for from a management team. Doing everything right, yet thw shares are 50% off where they reasonably should be in my mind.

microcapspeculator Posted - 2 days ago

$COYA Coya Therapeutics (COYA): Rodman and Renshaw PT $17 Letter to Shareholders November 19th,2024 https://coyatherapeutics.wordpress.com/2024/11/19/coya-therapeutics-coya-rodman-and-renshaw-pt-17-letter-to-shareholders-november-19th2024/

microcapspeculator Posted - 2 days ago

$COYA Shareholders letter. https://ir.coyatherapeutics.com/news/news-details/2024/Coya-Therapeutics-CEO-Dr.-Arun-Swaminathan-Issues-Letter-to-Stockholders/default.aspx

Madmone Posted - 2 days ago

$COYA Another dead day. We need news

Zivnif02 Posted - 6 days ago

$COYA So you have: 1. Insiders buying 2. Recent significant pullback from a general misunderstanding of results that will actually help future trials 3. Another pullback after the original pullback due to fear of a RFK being appointed health secretary. 4. A company that has a significant cash runway and has partnered with a large player in the industry. Sounds like a perfect time to buy.

foreverboner Posted - 6 days ago

$COYA FUD around RFK JR appointment will create a lot of incredible opportunities.

microcapspeculator Posted - 6 days ago

$COYA CFO buying some shares.

EmotionlessRobot Posted - 6 days ago

$COYA Very solid company

VGstocksup Posted - 1 week ago

$COYA Bought

Zivnif02 Posted - 1 week ago

$COYA lots of reasons insiders may sell.. only 1 reason they buy.. ⬆️⬆️⬆️

Jwa68 Posted - 1 week ago

$COYA Always a nice sign and confidence builder when the CEO puts sone money where his mouth is. That's about $75k he has spent in the last two days. Anyone who knows Arun personally knows that he is a world class executive and quality human being.

microcapspeculator Posted - 1 week ago

$COYA More CEO insider buying.

Jwa68 Posted - 1 week ago

$COYA Always nice to see insiders buy in the open market, putting their own money where their mouth is.

microcapspeculator Posted - 1 week ago

$COYA CMO buying shares.

microcapspeculator Posted - 1 week ago

$COYA New CEO buying 5000 shares. Nice.

CN545 Posted - 1 week ago

$GANX $COYA wish the bleeding would end so that I can stop feeling compelled to buy more.

microcapspeculator Posted - 1 week ago

$COYA Full H.C Wainwright report. Coya Therapeutics (COYA): H. C. Wainwright Buy $18 PT - Positive IL-2 Data https://coyatherapeutics.wordpress.com/2024/11/11/coya-therapeutics-coya-h-c-wainwright-buy-18-pt-positive-il-2-data/

microcapspeculator Posted - 1 week ago

$COYA Here is the H.C. Wainwright update. A very busy 2025 and cash into 2026.

Mulhollandr Posted - 1 week ago

@Jethro18 I understand your perspective. I was simply trying to highlight the potential promising treatments coming down the pipe. Though I get that 2 years feels far off. I should have also mentioned $COYA

microcapspeculator Posted - 1 week ago

$COYA I noticed that Howard liked this article. I believe it is since Coya-302 can stop the inflammation it could stop AD. https://www.thetransmitter.org/alzheimers-disease/early-trajectory-of-alzheimers-tracked-in-single-cell-brain-atlases/ The inflammation signal came as no surprise, she adds, but the order in which these changes seem to happen was unexpected. Causal mediation modeling of the data showed a link between the inflammatory response of one microglia subgroup and an increase in plaques, and a connection between the activation of another microglia subgroup and the progression from plaques to tangles. From there, astrocytes mediated a connection between increased tangles and cognitive decline. That means, she says, that this inflammation is not just “collateral damage” but a critical step needed for Alzheimer’s to progress.

DB32022 Posted - 1 week ago

$COYA Has there been any mention lately of participation in Healey? I know that it is common for a public announcement 6-7 months prior to a start date with Healey. This very well could explain the delay of starting the ALS trial. would be nice to participate in healey given that it would save money and significant recruiting patients.

microcapspeculator Posted - 1 week ago

$GANX $COYA Another phase 1 for over a billion. AbbVie is buying Aliada Therapeutics for $1.4 billion. It is AbbVie’s third acquisition this year and its first in the neuroscience space since the firm bought Cerevel Therapeutics and its late-stage antipsychotic for $8.7 billion last year. AbbVie gains ALIA-1758, an anti-amyloid antibody currently in Phase I clinical trials as a treatment for Alzheimer’s disease, as well as Aliada’s modular delivery platform, which uses small proteins to deliver cargoes across the blood-brain barrier.

buffalochips62 Posted - 1 week ago

$COYA hello, near here. What was behind the recent runup and then drastic drop?

microcapspeculator Posted - 1 week ago

$COYA BTIG Report $15 Target. Coya Therapeutics (COYA): BTIG Buy $15 PT - 3Q24 Financials Signs of Efficacy for Coya-301 in AD https://coyatherapeutics.wordpress.com/2024/11/07/coya-therapeutics-coya-btig-buy-15-pt-3q24-financials-signs-of-efficacy-for-coya-301-in-ad/

microcapspeculator Posted - 2 weeks ago

$COYA This slide from BTIG report shows why they think COYA-302 will at least slow down FTD if not actually stop progression. I imagine that could start at any time.

Jwa68 Posted - 2 weeks ago

$COYA Nice report out from BTIG, BUY $15 target. Signs of efficacy in COYA301 in AD at the CTAD Presentation Help Derisk COYA302 in ALS.

kornlover Posted - 2 weeks ago

$COYA Per Fintel, Vanguard Group filed 13G/A for 845K shares and 5.5% ownership....hopefully we see some appreciation in the next 12-18 months.

microcapspeculator Posted - 2 weeks ago

$COYA There is an updated presentation that goes along with today's release. They have around $40m in cash and will receive over $8m when first ALS patient is dosed. Burn rate maybe $3-4m/quarter so they are set for cash for at least next several years. The FTD study looks like 5 to start and another 5 after that.

DB32022 Posted - 2 weeks ago

$COYA ALS not beginning until Q2