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Market Cap 672.16M P/E - EPS this Y -5.10% Ern Qtrly Grth -
Income -157.35M Forward P/E -3.53 EPS next Y -6.10% 50D Avg Chg 17.00%
Sales 6.85M PEG - EPS past 5Y - 200D Avg Chg 60.00%
Dividend N/A Price/Book 2.28 EPS next 5Y - 52W High Chg -19.00%
Recommedations 1.60 Quick Ratio 12.78 Shares Outstanding 113.31M 52W Low Chg 134.00%
Insider Own 1.55% ROA -24.54% Shares Float 76.09M Beta 1.45
Inst Own 77.59% ROE -55.84% Shares Shorted/Prior 1.97M/1.38M Price 7.03
Gross Margin 100.00% Profit Margin - Avg. Volume 183,362 Target Price 24.00
Oper. Margin -2,268.45% Earnings Date - Volume 2,271,839 Change -5.13%
About Centessa Pharmaceuticals plc

Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines for patients. Its products pipeline includes SerpinPC, an activated protein C inhibitor for the treatment of hemophilia A and B; and ORX750, an orally administered OX2R agonist for the treatment of narcolepsy and other sleep disorders. The company also develops LB101, a PD-L1xCD47 LockBody, a bi-specific monoclonal antibody for solid tumors, which is designed to selectively drive potent CD47 and CD3 effector function activity while avoiding systemic toxicity; and OX2R Agonists compounds are currently in development for the treatment of narcolepsy. In addition, its products pipeline comprises ORX750, an orally administered selective orexin receptor-2 (OX2R) agonist for the treatment of narcolepsy and other sleep disorders; and earlier-stage preclinical assets and discovery-stage programs. Centessa Pharmaceuticals plc was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Centessa Pharmaceuticals plc News
09/12/24 Centessa Pharmaceuticals Announces Pricing of Upsized $225,000,000 Public Offering of American Depositary Shares
09/11/24 Centessa Pharmaceuticals Announces $150,000,000 Proposed Public Offering of American Depositary Shares
09/10/24 Centessa Reverses Lower Despite $5 Billion Narcolepsy Opportunity
09/10/24 Top Midday Gainers
09/10/24 Sleep-Disorder Focused Centessa Pharmaceuticals Unveils Interim Data From Lead Program In Acutely Sleep-Deprived Healthy Volunteers
09/10/24 Investors are waking up to Centessa’s sleepiness drug
09/10/24 Centessa Announces Positive Interim Phase 1 Clinical Data with its Novel Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Volunteers
08/27/24 Centessa Pharmaceuticals Announces Late-Breaking Poster Presentation of Non-Human Primate Data for ORX142, a Novel Orexin Receptor 2 (OX2R) Agonist, at the 27th Congress of the European Sleep Research Society (Sleep Europe 2024)
08/24/24 Insider Sale: Chief Business Officer Gregory Weinhoff Sells 30,000 Shares of Centessa ...
08/21/24 Centessa Pharmaceuticals to Participate in the Morgan Stanley 22nd Annual Global Healthcare Conference
01:17 PM Centessa Pharmaceuticals plc's (NASDAQ:CNTA) high institutional ownership speaks for itself as stock continues to impress, up 18% over last week
08/13/24 Centessa Pharmaceuticals Reports Financial Results and Business Highlights for the Second Quarter of 2024
07/31/24 Are Medical Stocks Lagging Stryker (SYK) This Year?
07/16/24 Wall Street Analysts Believe Centessa Pharmaceuticals (CNTA) Could Rally 48.85%: Here's is How to Trade
06/10/24 Centessa Pharmaceuticals Strengthens Executive Leadership with Appointment of John Crowley CPA, as Chief Financial Officer and Gregory Weinhoff MD MBA, as Chief Business Officer
05/28/24 Down -10.98% in 4 Weeks, Here's Why You Should You Buy the Dip in Centessa Pharmaceuticals (CNTA)
05/21/24 Centessa Pharmaceuticals to Participate in Upcoming Investor Conferences
05/13/24 Centessa Pharmaceuticals Reports Financial Results and Business Highlights for the First Quarter of 2024
04/23/24 Centessa Pharmaceuticals Announces Pricing of $100 Million Public Offering of American Depositary Shares
04/23/24 Centessa Pharmaceuticals Announces $100 Million Proposed Public Offering of American Depositary Shares
CNTA Chatroom

User Image DonCorleone77 Posted - 8 hours ago

$CNTA Morgan Stanley upgrades Centessa on 'best-in-class' potential of ORX750 Morgan Stanley upgraded Centessa to Overweight from Equal Weight with a price target of $26, up from $11. The firm had been "cautiously optimistic heading" into the Phase 1 readout based on safety signals seen with competing candidates in the space, but it now contends following the recent report of topline ORX750 Phase 1 results in healthy volunteers that the data "remove the largest overhang on the orexin 2 field and confirm it has potential to be best-in-class for treating narcolepsy." The firm updated its model and now includes market models for ORX750 in narcolepsy type 2 and idiopathic hypersomnia, the analyst noted.

User Image basscat12 Posted - 17 hours ago

$DASH $PRLD $CNTA Pre-Market Mash-Up, page 4, Highlighted Analyst Activity, courtesy @TheTradeXchange , the Best Squawk On The Street, and presented with @Vegas1 to help prepare for today's market!

User Image AnaChart Posted - 3 days ago

$CNTA https://anachart.com/wp-content/uploads/ana_temp/1726491703_soc-img.jpg

User Image tradingtwenty Posted - 6 days ago

$CNTA has trended 21 times in the past 24 hours (based on 5 minute intervals). Latest press release on Sep 12, 2024 10:34 PM: Centessa Pharmaceuticals Announces Pricing of Upsized $225,000,000 Public Offering of American Depositary Shares Link: https://tradingtwenty.com/news/620806/centessa-pharmaceuticals-announces-pricing-of-upsized-225000000-public-offering-of-american-depositary-shares

User Image DonCorleone77 Posted - 6 days ago

$CNTA Centessa 15.25M share Spot Secondary priced at $14.75 The deal size was increased to 15.2M shares from 10.9M and priced below last closing price of $15.10. Goldman Sachs, Leerink, Evercore ISI, Guggenheim and BMO Capital acted as joint book running managers for the offering.

User Image insiderbuyingselling Posted - 1 week ago

$CNTA new insider selling: 30000 shares. http://insiderbuyingselling.com/?t=CNTA

User Image Stock_Titan Posted - 1 week ago

$CNTA Centessa Pharmaceuticals Announces Pricing of Upsized $225,000,000 Public Offering of American Depositary Shares https://www.stocktitan.net/news/CNTA/centessa-pharmaceuticals-announces-pricing-of-upsized-225-000-000-nzivvvv3kw2a.html

User Image StockInvest_us Posted - 1 week ago

Signal alert: $CNTA - Overbought Trend Short (Overvalued) https://stockinvest.us/l/qS6ND51Dl4

User Image Stock_Titan Posted - 1 week ago

$CNTA Centessa Pharmaceuticals Announces $150,000,000 Proposed Public Offering of American Depositary Shares https://www.stocktitan.net/news/CNTA/centessa-pharmaceuticals-announces-150-000-000-proposed-public-65fqu0xjmriq.html

User Image Thestocktraderhubzee Posted - 1 week ago

$CNTA Guggenheim Maintains Buy on Centessa Pharmaceuticals, Raises Price Target to $24

User Image 30DeltaSpy Posted - 1 week ago

$CNTA $5 billion dollar narcolepsy opportunity

User Image 1UpOnWallStreet Posted - 1 week ago

$CNTA Good buy here. Reversal now.

User Image Will2ride1 Posted - 1 week ago

$CNTA congrats if you followed 🍻

User Image GetVector Posted - 1 week ago

Vector Intelligence (VI) is an algorithm designed to predict potential outsized intraday moves. VI will select up to 4 stocks per day. Today's VI stocks: $CNTA, $VRDN.

User Image DonCorleone77 Posted - 1 week ago

$CNTA Centessa announces interim data from ongoing Phase 1 trial of ORX750 Centessa Pharmaceuticals announced positive interim data from an ongoing Phase 1 trial of its highly potent and selective orexin receptor 2 agonist, ORX750, in acutely sleep-deprived healthy volunteers. ORX750 showed clinically meaningful and statistically significant improvements in mean sleep latency at the first two doses evaluated in the Maintenance of Wakefulness Test, MWT, compared to placebo. More specifically, the 2.5 mg dose was shown to restore normative wakefulness2 with a mean sleep latency of 32 minutes as measured by the MWT. ORX750 was also shown to have a favorable safety and tolerability profile with no observations of frequently reported on-target adverse events, AEs, associated with other OX2R agonists, and no cases of hepatotoxicity or visual disturbances across all three dose levels tested, as of the data cutoff date.1 Based on the interim data, the Company plans to rapidly advance ORX750 into Phase 2 studies in patients with narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia beginning in the fourth quarter of 2024.

User Image briefingcom Posted - 1 week ago

Gapping up: $AVO +21.1% $CNTA +15.2% $VRDN +12.7% $MTRX +8.3% $ORCL +8.2%

User Image Thestocktraderhubzee Posted - 1 week ago

$CNTA Centessa Pharmaceuticals Announced Interim Data From An Ongoing Phase 1 Trial Of ORX750, In Acutely Sleep-deprived Healthy Volunteers, Showing Clinically Meaningful And Statistically Significant Improvements In Mean Sleep Latency At The First Two Doses Evaluated Vs. Placebo

User Image Stock_Titan Posted - 1 week ago

$CNTA Centessa Announces Positive Interim Phase 1 Clinical Data with its Novel Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Volunteers https://www.stocktitan.net/news/CNTA/centessa-announces-positive-interim-phase-1-clinical-data-with-its-0e5y8o18asqn.html

User Image AnaChart Posted - 1 week ago

$CNTA https://anachart.com/wp-content/uploads/ana_temp/1725886890_soc-img.jpg

User Image PenkeTrading Posted - 2 weeks ago

I found you an Overbought RSI (Relative Strength Index) on the daily chart of Centessa Pharmaceuticals PLC ADR. Is that bullish or bearish? $CNTA #CNTA #nasdaq #tradingsignals #technicalanalysis

User Image QuantData Posted - 08/28/24

We have identified an unusual $CNTA block that expires on September 20, 2024 with a strike price of $15.00 5,000 CALL contracts with a price of $1.20 (Bid) were sold at a $600,000 premium. The price of $CNTA at the time of execution (12:35 PM ET) was $13.60

User Image DonCorleone77 Posted - 08/27/24

$CNTA Centessa to present non-human primate data for ORX142 at Sleep Europe 2024 Centessa Pharmaceuticals announced that preclinical data from a non-human primate study of ORX142, a highly potent and selective orexin receptor 2 agonist being developed to address excessive daytime sleepiness in select neurological, neurodegenerative, and psychiatric disorders, has been accepted for a late- breaking poster presentation at the 27th Congress of the European Sleep Research Society being held September 24-27, 2024, in Seville, Spain. The poster presentation will feature, for the first time, robust preclinical data demonstrating that low doses of ORX142 promoted wakefulness in non-human primates in a highly predictive and translational model. "ORX142 is the second drug candidate from our growing pipeline of potentially best-in-class OX2R agonists that has shown significant activity in promoting wakefulness at very low doses in highly predictive and translational preclinical models," said Saurabh Saha MD PhD, Chief Executive Officer of Centessa. "We believe these non-human primate data are compelling as they demonstrate the potential for ORX142, a highly potent and novel OX2R agonist, to alleviate excessive daytime sleepiness in select neurological, neurodegenerative, and psychiatric disorders with no significant loss of orexin. We are thrilled to be sharing these preclinical data in a late-breaking presentation at Sleep Europe 2024."

User Image Stock_Titan Posted - 08/27/24

$CNTA Centessa Pharmaceuticals Announces Late-Breaking Poster Presentation of Non-Human Primate Data for ORX142, a Novel Orexin Receptor 2 (OX2R) Agonist, at the 27th Congress of the European Sleep Research Society (Sleep Europe 2024) https://www.stocktitan.net/news/CNTA/centessa-pharmaceuticals-announces-late-breaking-poster-presentation-buuuc13w75ph.html

User Image FlynancialAnalyst Posted - 1 month ago

$CNTA ... this one's special Following latest data, Pct of all funds long shares is now at record highs as its rise continues $20+ on deck

User Image Thestocktraderhubzee Posted - 1 month ago

$CNTA Oppenheimer Reiterates Outperform on Centessa Pharmaceuticals, Maintains $14 Price Target

User Image Stock_Titan Posted - 1 month ago

$CNTA Centessa Pharmaceuticals Reports Financial Results and Business Highlights for the Second Quarter of 2024 https://www.stocktitan.net/news/CNTA/centessa-pharmaceuticals-reports-financial-results-and-business-3cakklbz6hvk.html

User Image FlynancialAnalyst Posted - 1 month ago

$CNTA with some fantastic follow thru on volume! $XBI leaders wants $20+ DD ^^ in thread above all the same

User Image Wigglyick Posted - 1 month ago

$CNTA Centessa Pharma, developing therapies for unmed needs in a variety of areas. @FlynancialAnalyst has highlighted this stock a number of times and it has a great chart. So stop drooling into your pillow and do some DD.

User Image FlynancialAnalyst Posted - 1 month ago

$CNTA $1.16B mc $XBI #HiddenGem (only 167 watchers on Stocktwits) with a low volume rinse into rising 10/40 wk SMAs Pct of all funds long shares is at record highs Short float % is at record lows TrendEdge.app/asset/CNTA

User Image NVDAMillionaire Posted - 07/30/24

$CNTA Centessa Pharmaceuticals (CNTA): A Promising Biotech Poised for Transformative Breakthroughs http://beyondspx.com/2024/07/30/centessa-pharmaceuticals-cnta-a-promising-biotech-poised-for-transformative-breakthroughs/

Analyst Ratings
Morgan Stanley Overweight Sep 19, 24
B. Riley Securities Buy Sep 19, 24
BMO Capital Outperform Sep 16, 24
Guggenheim Buy Sep 11, 24
Jefferies Buy Sep 11, 24
BMO Capital Outperform Sep 9, 24
Oppenheimer Outperform Aug 14, 24
Oppenheimer Outperform Jul 18, 24
Morgan Stanley Equal-Weight Jun 21, 24
Insider Trades Relationship Date Transactions Cost($) #Shares Value($) #Share Own SEC Form 4
Rotman Harris SVP Regulatory Affai.. SVP Regulatory Affairs Feb 01 Sell 8.1 4,267 34,563 62,625 02/02/24
Rotman Harris SVP Regulatory Affai.. SVP Regulatory Affairs Sep 20 Sell 6.29 37,484 235,774 33,500 09/22/23
Rotman Harris SVP Regulatory Affai.. SVP Regulatory Affairs Sep 20 Option 4.16 37,484 155,933 70,984 09/22/23
Bush Tia L Chief Quality Office.. Chief Quality Officer May 24 Sell 4.48 8,000 35,840 05/26/23
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Mar 01 Sell 3.4243 7,000 23,970 806,681 03/03/23
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Dec 31 Sell 3.18 6,970 22,165 751,913 01/04/23
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Sep 30 Sell 3.9061 9,500 37,108 780,251 11/23/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Sep 01 Sell 4.4121 10,423 45,987 789,751 09/02/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Aug 01 Sell 4.4522 10,423 46,405 800,174 08/03/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Jul 18 Sell 4.8656 20,000 97,312 810,597 07/20/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Jul 01 Sell 5.03 9,100 45,773 730,597 07/06/22
SAHA SAURABH Chief Executive Offi.. Chief Executive Officer Jun 24 Buy 4.6284 10,000 46,284 38,000 06/27/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development Jun 17 Sell 4.6778 9,200 43,036 739,697 06/21/22
YVER ANTOINE EVP & Chairman of De.. EVP & Chairman of Development May 17 Sell 5.26 85,000 447,100 748,897 05/19/22
SAHA SAURABH Chief Executive Offi.. Chief Executive Officer Feb 02 Buy 9.74 5,000 48,700 28,000 02/04/22
GRAINGER DAVID J Chief Innovation Off.. Chief Innovation Officer Jan 28 Buy 9.0456 27,500 248,754 27,500 02/01/22
De Rubertis Francesco Director Director Nov 30 Buy 12.12 97,151 1,177,470 92,730 12/02/21
De Rubertis Francesco Director Director Nov 26 Buy 11.52 68,523 789,385 90,476 11/30/21