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Market Cap 111.07M P/E - EPS this Y 32.40% Ern Qtrly Grth -
Income -161.09M Forward P/E -1.73 EPS next Y 56.30% 50D Avg Chg 35.00%
Sales -333k PEG - EPS past 5Y - 200D Avg Chg 75.00%
Dividend N/A Price/Book N/A EPS next 5Y - 52W High Chg -12.00%
Recommedations 1.30 Quick Ratio 2.21 Shares Outstanding 114.85M 52W Low Chg 284.00%
Insider Own 5.31% ROA -56.90% Shares Float 83.26M Beta 2.03
Inst Own 95.38% ROE -473.39% Shares Shorted/Prior 10.82M/9.56M Price 1.92
Gross Margin - Profit Margin - Avg. Volume 234,882 Target Price 12.80
Oper. Margin -14,194.44% Earnings Date Nov 7 Volume 1,911,233 Change 12.28%
About Applied Therapeutics, Inc.

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. The company's lead product candidate is AT-007 (also called govorestat) that has completed phase 3 for the treatment of galactosemia in healthy volunteers and adults, in pediatric clinical study for the treatment of galactosemia in kids, for treating enzyme sorbitol dehydrogenase, and for the treatment of phosphomannomutase enzyme-CDG. It also develops AT-001 (also called caficrestat) that is in phase 3 clinical trials to treat diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy; and AT-003, which is in preclinical studies for the treatment diabetic retinopathy. The company has exclusive license and supply agreement with Mercury Pharma Group Limited to commercialize drug products containing AT-007. Applied Therapeutics, Inc. was incorporated in 2016 and is headquartered in New York, New York.

Applied Therapeutics, Inc. News
12/20/24 Penny Stock Applied Therapeutics' FDA Troubles Trigger Investor Lawsuit, Shareholders Claim Deception Over Govorestat Clinical Data
12/20/24 Applied Therapeutics Appoints John H. Johnson as Executive Chairman
12/03/24 Will Applied Therapeutics (NASDAQ:APLT) Spend Its Cash Wisely?
12/02/24 Applied Therapeutics Faces Uncertainty After US FDA Rejects NDA for Govorestat in Galactosemia, UBS Says
12/02/24 Company News for Dec 2, 2024
11/30/24 Applied Therapeutics CRL a ‘major setback,’ says William Blair
11/30/24 Applied Therapeutics downgraded to Sector Perform from Outperform at RBC
11/29/24 FDA Rejects Applied Therapeutics' NDA for Govorestat, Citing Flaws; Shares Plunge 76%
11/29/24 Biotech Stock Roundup: BBIO Stock Up on Drug Approval, SAVA, APLT Plunge on Setbacks & More
11/29/24 Top Midday Decliners
11/29/24 Sector Update: Health Care Stocks Rise in Afternoon Trading
11/29/24 Applied Therapeutics' Govorestat Faces 'Significant' Uncertainty in Galactosemia Treatment After FDA Rejection, RBC Says
11/29/24 Applied Therapeutics Stock Plummets 73%. The FDA Delivers This Crushing Blow.
11/29/24 Applied Therapeutics Stock Plummets After FDA Rejects Metabolic Disease Drug
11/29/24 Applied Therapeutics' Govorestat Faces Unclear Regulatory Path After FDA Rejection, RBC Says
11/29/24 RBC downgrades Applied Therapeutics as FDA rejects Govorestat, hacks price target
11/28/24 APLT Stock Plunges 77% After FDA Issues CRL for Galactosemia Drug NDA
11/28/24 Wait for galactosemia therapy goes on after FDA shuns Applied Therapeutics’ govorestat
11/27/24 Applied Therapeutics Receives Complete Response Letter from U.S. FDA Regarding New Drug Application for Govorestat for Classic Galactosemia
11/07/24 Applied Therapeutics Reports Third Quarter 2024 Financial Results
APLT Chatroom

User Image Stonkey Posted - 22 minutes from now

$APLT Racing to zero with the speed of light....

User Image 543688Ireland Posted - 42 minutes ago

$APLT Strategic Partnership news would be awesome! The company has been kinda quiet with top officials stepping down. This is Just speculation but it seems as if something is cooking. 🧑‍🍳

User Image 543688Ireland Posted - 2 hours ago

$APLT I’m not hating on the shorts here, the lower I can add the better. The sell off is ridiculous at this point, but I’m not complaining.

User Image RealInfo Posted - 4 hours ago

$APLT Hey , where are all of the EXPERTS who were saying in October and early November "Don't let THEM steal your shares...We're in this til the end!" I assume you are all buried in a hole somewhere cuz we don't hear you yapping anymore. Unless you're the idiots that keep saying BUY THE DIP everytime this POS goes down another 10 cents.

User Image RockBottomChartz Posted - 4 hours ago

$APLT ehhhh good morning.

User Image investmenteagle Posted - 22 hours ago

$APLT sell and take the tax loss write off. being Shendelman'ed is not cool. She'll be enjoying her Hanukah, while some of us will be in pain this Christmas.

User Image investmenteagle Posted - 22 hours ago

$APLT nobody found it sus that Shoshana Shendelman sold a chunk of her lot before the CRL?

User Image RockBottomChartz Posted - 23 hours ago

$APLT Merry Christmas from the Rock

User Image Article_AI Posted - 1 day ago

$APLT Analysts Are Bullish on Top Healthcare Stocks: Oruka Therapeutics (ORKA), Vertex Pharmaceuticals (VRTX) There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on Oruka Therapeutics (ORKA – Research Report), Vertex ... https://www.stck.pro/news/APLT/96895044/

User Image RealInfo Posted - 1 day ago

$APLT So none of you BULLS are concerned with the 18 law firms soliciting investors to join in a Class Action Lawsuit against Soshanna and her band of idiots? Yes, I realize she has left the building but her stench remains with the company forever. I know your reply is "BUY THE DIP"... The Day Trader's are playing the long term investors for the Fool's they are.

User Image 543688Ireland Posted - 1 day ago

$APLT Now that it’s only .85, I can follow this logic and train of thought. https://www.tipranks.com/news/blurbs/optimistic-outlook-for-applied-therapeutics-despite-fda-setback

User Image Germany2020 Posted - 1 day ago

$APLT what else in their pipeline guys? Wanna b&h for a year / two..

User Image alancg Posted - 1 day ago

$APLT It’s always the same; the time to buy is when everyone else is selling.

User Image DJW009 Posted - 1 day ago

$APLT 87% institutional holdings say you are wrong

User Image DJW009 Posted - 1 day ago

$APLT Let's hold out for $4.

User Image 543688Ireland Posted - 1 day ago

$APLT Taking a flyer here as I believe something positive will come of this soon. Not investment advice, I just have that feeling.

User Image Billions2020 Posted - 1 day ago

$APLT gimme $2.00 i will be gone!

User Image Hayaninvestr85 Posted - 1 day ago

$APLT MAGA (make ALPT great again)

User Image CAMDENBEER Posted - 1 day ago

$APLT tax loss harvesting will be here for the next few years. MANY people need to use losses to offset their winners in 2024. also, smart money needs to get the trash out of their portfolios before year end. you can't tell your investors you own trash like APLT

User Image JackLarson369 Posted - 1 day ago

$APLT Working to bottom here. Reversal risk/reward looks good.

User Image GoldmanSlaps Posted - 1 day ago

$APLT what is this greeen color?!?

User Image showmethemoney75 Posted - 1 day ago

$APLT We got rid of the devil let’s go!!!!

User Image showmethemoney75 Posted - 1 day ago

$APLT Jesus is now super bullish on this stock 20K shares long. Will go green. Looking for 1.25 by first week of new year!!!

User Image RockBottomChartz Posted - 1 day ago

$APLT volume increase.

User Image RockBottomChartz Posted - 1 day ago

$APLT fake sales. Nobody sells at the ATL.

User Image Stonkey Posted - 1 day ago

$APLT Bleeding to death with the speed of light....

User Image RockBottomChartz Posted - 2 days ago

$APLT new ceo. New path forward.

User Image BioIngenieur Posted - 2 days ago

$APLT Applied Therapeutics (APLT) offers an exciting investment opportunity with govorestat and a strong pipeline. Its orphan drug status provides benefits like seven years of market exclusivity, additional FDA support, and tax incentives, reducing regulatory risks and strengthening its market position. An FDA Complete Response Letter (CRL) is not uncommon and often surmountable. Examples like Tresiba and Brilinta demonstrate that approvals can follow after addressing concerns. Applied Therapeutics has strong potential to overcome similar challenges. Beyond classical galactosemia, govorestat is being developed for SORD deficiency (Phase 3) and PMM2-CDG (Phase 2). Additional assets like AT-001 and AT-003 diversify APLT’s portfolio, mitigating risks. With a market valuation of $100 million, APLT appears undervalued. Investors like Janus Henderson show confidence, and despite inherent risks, the company’s opportunities far outweigh the challenges.

User Image ys95 Posted - 2 days ago

$APLT .86 and yet we have buyers. Slowly returning shares too but still have a ways to go. Jmo

User Image mikeyd Posted - 2 days ago

$APLT who’s the co—-k gobbler that has to try and sell AH at .84, jackoff

Analyst Ratings
Citigroup Buy Sep 19, 24
Leerink Partners Outperform Sep 19, 24
Citigroup Buy Aug 27, 24
William Blair Outperform Jul 31, 24
RBC Capital Outperform Jul 17, 24
RBC Capital Outperform Apr 11, 24
RBC Capital Outperform Mar 26, 24
UBS Buy Mar 15, 24
UBS Buy Mar 6, 24
Insider Trades Relationship Date Transactions Cost($) #Shares Value($) #Share Own SEC Form 4
Kanter Stacy J. Director Director Dec 01 Buy 2.1789 30,000 65,367 63,000 12/05/23
Shendelman Shoshana President and CEO President and CEO Nov 30 Sell 1.97 3,968 7,817 2,596,387 12/01/23
Perfetti Riccardo Chief Medical Office.. Chief Medical Officer Nov 30 Sell 1.97 1,583 3,119 692,341 12/01/23
Hansard Adam Chief Commercial Off.. Chief Commercial Officer Nov 30 Sell 1.97 965 1,901 381,790 12/01/23
ALEXANDRIA REAL ESTATE EQUITIE... 10% Owner 10% Owner Nov 02 Sell 2.32 247,258 573,639 5,580,077 11/06/23
Shendelman Shoshana President and CEO President and CEO Sep 27 Sell 2.70 115,632 312,206 2,600,355 09/29/23
Perfetti Riccardo Chief Medical Office.. Chief Medical Officer Sep 27 Sell 2.70 10,932 29,516 693,924 09/29/23
Hansard Adam Chief Commercial Off.. Chief Commercial Officer Sep 27 Sell 2.70 9,720 26,244 382,755 09/29/23
MARCUS JOEL S Director Director Sep 15 Option 1.05 12,375 12,994 453,414 09/19/23
Hansard Adam Chief Commercial Off.. Chief Commercial Officer Jan 11 Sell 0.91 4,495 4,090 92,475 01/13/23
Shendelman Shoshana President and CEO President and CEO Oct 12 Buy 0.5227 38,153 19,943 644,239 10/12/22
MARCUS JOEL S Director Director Apr 14 Option 7.35 48,982 360,018 67,435 09/16/22
MARCUS JOEL S Director Director Sep 14 Option 1.05 38,244 40,156 421,039 09/16/22
ALEXANDRIA REAL ESTATE EQUITIE... 10% Owner 10% Owner Jun 27 Buy 1 3,500,000 3,500,000 4,555,077 06/29/22
Mahadevan Chids See Remarks See Remarks May 16 Sell 1.65 905 1,493 9,800 05/18/22
Perfetti Riccardo Chief Medical Office.. Chief Medical Officer Mar 21 Buy 1.93 64,509 124,502 160,909 03/23/22
Shendelman Shoshana President and CEO President and CEO Sep 14 Buy 14.59 10,001 145,915 364,286 09/14/21