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Market Cap 35.64M P/E - EPS this Y 44.70% Ern Qtrly Grth -
Income -28.18M Forward P/E -1.39 EPS next Y 5.20% 50D Avg Chg -15.00%
Sales - PEG - EPS past 5Y - 200D Avg Chg -33.00%
Dividend N/A Price/Book 1.11 EPS next 5Y - 52W High Chg -64.00%
Recommedations 2.20 Quick Ratio 0.95 Shares Outstanding 2.25M 52W Low Chg 8.00%
Insider Own 0.53% ROA -68.43% Shares Float 39.21M Beta 1.02
Inst Own 15.49% ROE -180.77% Shares Shorted/Prior 62.45K/44.11K Price 0.68
Gross Margin - Profit Margin - Avg. Volume 42,411 Target Price 87.84
Oper. Margin - Earnings Date Nov 14 Volume 137,843 Change -9.29%
About NuCana plc

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company, through its technology, is developing ProTides medicines to overcome the limitations of nucleoside analogs and generate much higher concentrations of anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer, Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer, and Phase 1b/2 modular clinical trial for patients with advanced solid tumors and lung cancer. It is also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. The company has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is headquartered in Edinburgh, the United Kingdom.

NuCana plc News
11/11/24 NuCana Announces Encouraging Initial Data from Phase 1b/2 Modular Study of NUC-3373 in Combination with Pembrolizumab or Docetaxel
09/25/24 NuCana Announces Grant of Composition-of-Matter Patent for NUC-7738 in the United States
09/17/24 NuCana Stock Soars 151% on Upbeat Efficacy Data From Melanoma Study
09/16/24 NuCana's Encouraging Data From Resistant Melanoma Treatment Provides Some Relief After Disappointing Colorectal Cancer Data, Stock Surges
09/14/24 NuCana Presents Encouraging Data on NUC-7738 in Combination with Pembrolizumab in PD-1 Inhibitor Refractory and Resistant Melanoma Patients at the ESMO Congress 2024
08/30/24 Top Midday Decliners
08/30/24 NuCana Stock Plunges On Colorectal Combo Therapy Trial Setback, Ends Mid-Stage Study After Disappointing Data
08/30/24 NuCana discontinues Phase II NuTide:323 colorectal cancer study
08/29/24 NuCana Announces Update for Phase 2 Randomized Colorectal Cancer Study
07:16 AM We're A Little Worried About NuCana's (NASDAQ:NCNA) Cash Burn Rate
08/15/24 NuCana Reports Second Quarter 2024 Financial Results and Provides Business Update
05/30/24 NuCana to Present at the Jefferies Global Healthcare Conference
07:00 AM NuCana to Present at TD Cowen’s 5th Annual Oncology Innovation Summit
05/16/24 NuCana Reports First Quarter 2024 Financial Results and Provides Business Update
05/01/24 NuCana Regains Compliance with Nasdaq Minimum Bid Price Requirement
04/16/24 NuCana Announces Completion of ADS Ratio Change
04/09/24 NuCana Presents Data at the AACR 2024 Annual Meeting Highlighting the Ability of NUC-7738 to Profoundly Alter Tumor Biology in a Paired Biopsy Clinical Study
03/27/24 NuCana Announces Plan to Implement ADS Ratio Change
03/20/24 NuCana Reports Fourth Quarter and Year-End 2023 Financial Results and Provides Business Update
03/14/24 NuCana (NASDAQ:NCNA) Will Have To Spend Its Cash Wisely
NCNA Chatroom

User Image GuineaPigForever Posted - 6 hours ago

$NCNA I find myself hoping this drops more because it is so great getting so many more shares even cheaper. With this float size, all this needs is a successful phase 2 and I believe it goes crazy. I believe it has been shorted hard in the dark pool and they are droping this on low volume with 100 share lot trades and small 1 share trades to "ping" the dark pool for liquidity. I have been early on a few of these now and they are great when fomo sets in.

User Image frontiere Posted - 7 hours ago

@Tjhale88 FYI your source is wrong (or that field means smth different from sell-side targets?) Here’s all the sell-side targets for $NCNA NuCana. Also FYi — ignore sell-side altogether, in 90% cases it’s irrelevant. They serve as feeders for other business within those shops (usually to win deals / advisory). But as you’ve seen we at @frontiere are bullish and long for other, fundamental reasons.

User Image frontiere Posted - 1 day ago

$NCNA NuCana ref=$1.30 — buying more on the way down. 👍Good news from ClinicalTrials gov : they updated on 2024-11-08 the NuTide701 Ph1/2 open label Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma 2024-11-08 (prior change in April) Study Status Study Description Study Design Eligibility https://clinicaltrials.gov/study/NCT03829254?term=Nucana&rank=5&tab=history&a=10&b=11#version-content-panel 👍+ other catalysts and neg EV as per prior post:

User Image PenkeTrading Posted - 1 day ago

I found you an Oversold RSI (Relative Strength Index) on the daily chart of NuCana PLC. Is that bullish or bearish? $NCNA #NuCana #RsiOversold #NASDAQ

User Image Tjhale88 Posted - 2 days ago

$NCNA still holding on for a reversal

User Image pee_dee Posted - 2 days ago

$TLRY $NCNA New all time lows day after day. The arteries have been cut and the only good news is that there’s not much blood left. Now cautiously short-term bullish (for a change) here for a reversal. But long-term still bearish for both.

User Image frontiere Posted - 2 days ago

$NCNA NuCana ref=$1.33 — a small clumsy sale order of 46000 shares into a low depth book gets us down 7% 🤪 Bought a bit more ! Prior post https://stocktwits.com/frontiere/message/592050090

User Image Lostwizard Posted - 2 days ago

$NCNA well, better safe than sorry, not more on this one. Good luck with a miracle.

User Image Itinerant Posted - 2 days ago

$NCNA I said the other day: I think this company is fucked by tax loss selling until late December. I am out. It can easily drop 75% IMO.

User Image HoHoHoHum Posted - 2 days ago

$NCNA collapsing. Wow!

User Image MadMaverick Posted - 2 days ago

⚡MORNING WATCHLIST⚡ $NCNA Entry above: $.263 🎯 $.285/$.30 🛑 $.25 $PRFX Entry above: $1.40 🎯 $1.55/$1.70 🛑 $1.32 $TRNR Entry above: $4.15 🎯 $4.30/$4.50 🛑 $4.05 $WBUY Entry above: $.23 🎯 $.25/$.27 🛑 $.215 Note: These are trade ideas based on break-out levels, once they hit entry & start moving up, consider raising your stops to protect your profits and protect your downside according to your own trading plan :). I personally trade these on either the 2 or 3 minute timeframes, waiting for a candle to close over the entry level.

User Image Itinerant Posted - 3 days ago

$NCNA I suspect that this name is in tax loss selling mode until the New Year, regrettably.

User Image David_Shitchery Posted - 3 days ago

$NCNA Very reminiscent of WHLR a couple months ago. https://seekingalpha.com/article/4638508-elevai-labs-seeks-micro-ipo-despite-little-revenue

User Image Bulltrader988 Posted - 3 days ago

$NCNA good news and this is gone...

User Image Tjhale88 Posted - 3 days ago

$NCNA I get the vibe this is purposely being forced to stay down

User Image GuineaPigForever Posted - 1 week ago

$NCNA of the last 20 trades I can see 19 of them were in round lots of 100. I am just guessing here, but it looks like someone is keeping price right here and loading up. I am likely wrong though.

User Image GuineaPigForever Posted - 1 week ago

$NCNA most trades are showing in lots of 100 shares. I think this indicates mostly institutions and funds trading this. They lot them for many reasons (give it a read about why they do this its interesting stuff). Also read about the many 1 share trades. Interesting reasons they do that too (they are "pinging" for liquidity) at different prices.

User Image Tjhale88 Posted - 1 week ago

$NCNA price target just doubled overnight. Was a consistent $22.50 for the last 2-3 weeks

User Image GuineaPigForever Posted - 1 week ago

$NCNA I have a feeling something is happening after hours today.

User Image Bulltrader988 Posted - 1 week ago

$NCNA Corporate presentation was updated this month https://ir.nucana.com/static-files/192fe3fc-979e-4de2-be34-aa2ee85b481f

User Image RollingDollars Posted - 1 week ago

$NCNA

User Image GREGORYARCHANGEL Posted - 1 week ago

$NCNA Look at the last three daily candles.

User Image Cruso Posted - 1 week ago

$NCNA NuCana’s recent Phase 1b/2 study results reveal promising efficacy of its new drug NUC-3373 in combination with pembrolizumab and docetaxel for patients with advanced solid tumors and lung cancer, respectively. Notably, patients who had exhausted other treatments demonstrated significant tumor reduction and prolonged progression-free survival. These developments could position NUC-3373 as a valuable option for hard-to-treat cancer cases, potentially impacting NuCana’s market performance.

User Image frontiere Posted - 1 week ago

$NCNA NuCana ref=$1.56 — LONG and added more here for our 5th spin of the roulette 👍Neg EV — 3.79m sh outst, cash=$18m pro forma as of 2024-09-30 =$4.77 per sh=3.1x mkt price (since 30 June till today raised ~$6.52m on spikes issuing 1.52m new shs at weighted-ave $4.29 per sh not bad👍, burn per Qtr=$2.44m, ~7 Qtrs runway). If nothing happens for this and a next Qtr, after 2025-03-31 cash per sh=$3.46 still 2.2x today’s mkt price!👍 Catalysts into end 2024 + early 2025 (precise timing unclear): 👍NUC-3373 NuTide:303 Ph1b/2 combo w pembrolizumab / docexatel — announce data (open label👍) — last updated 2024-09-26 https://clinicaltrials.gov/study/NCT05714553 👍NUC-7738 NuTide:701 Ph1/2 (open label👍) — initiate expansion, announce data, pivotal study — last updated 2024-04-04 https://clinicaltrials.gov/study/NCT03829254 . Updated Oct deck https://ir.nucana.com/static-files/97bb2838-ada0-4b88-8212-10d8d24b6f8c Today’s publ https://www.medrxiv.org/content/10.1101/2024.11.07.24316829v1

User Image Barker2258 Posted - 1 week ago

$NCNA $AREB

User Image WolfofFraudStreet Posted - 1 week ago

$NCNA The new is not great but they still may want to squeeze this one more time as most reailers are shorting this and the low float may go balistic

User Image Barker2258 Posted - 1 week ago

$NCNA $CERO

User Image Stocktwit247 Posted - 1 week ago

$NCNA should pump on the open.. UK stock, listed on Nasdaq.. US traders aren't interested in pre-market. ON WATCH

User Image buythedip_not_the_rip Posted - 1 week ago

$NCNA same news like CERO and no movement here ! Weird

User Image G101SPM Posted - 1 week ago

CORRECTION $NCNA SPM 85.95 tag not SPM 75.95 tag.

Analyst Ratings
Oppenheimer Outperform Aug 19, 24
Oppenheimer Outperform Jul 23, 24
Oppenheimer Outperform Jul 22, 24
Oppenheimer Outperform Apr 1, 24
Oppenheimer Outperform Nov 21, 23
Truist Securities Buy Sep 6, 23
Oppenheimer Outperform Aug 18, 23
Oppenheimer Outperform May 22, 23
Jefferies Buy Sep 22, 22