Market Cap | 23.29B | P/E | - | EPS this Y | 29.30% | Ern Qtrly Grth | - |
Income | -72.94M | Forward P/E | -81.66 | EPS next Y | 43.80% | 50D Avg Chg | -4.00% |
Sales | 2.34B | PEG | 0.62 | EPS past 5Y | - | 200D Avg Chg | -10.00% |
Dividend | N/A | Price/Book | N/A | EPS next 5Y | -177.50% | 52W High Chg | -23.00% |
Recommedations | 2.00 | Quick Ratio | 2.78 | Shares Outstanding | 128.38M | 52W Low Chg | 4.00% |
Insider Own | 0.42% | ROA | 1.73% | Shares Float | 127.84M | Beta | 0.38 |
Inst Own | 95.62% | ROE | - | Shares Shorted/Prior | 4.45M/4.52M | Price | 187.01 |
Gross Margin | 87.00% | Profit Margin | -3.11% | Avg. Volume | 556,961 | Target Price | 289.58 |
Oper. Margin | 7.37% | Earnings Date | Oct 31 | Volume | 618,142 | Change | -1.08% |
Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. Its marketed products include ONPATTRO (patisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; AMVUTTRA for the treatment of hATTR amyloidosis with polyneuropathy in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria; and OXLUMO for the treatment of primary hyperoxaluria type 1. In addition, the company develops patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; Belcesiran for the treatment of alpha-1 liver disease; Elebsiran to treat chronic HBV infection; Zilebesiran to treat hypertension; ALN-APP to treat Alzheimer's disease and cerebral amyloid angiopathy; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Roche to develop pharmaceutical products containing zilebesiran. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.
Insider Trades | Relationship | Date | Transactions | Cost($) | #Shares | Value($) | #Share Own | SEC Form 4 |
---|---|---|---|---|---|---|---|---|
Garg Pushkal | CMO & EVP Dev & Med.. CMO & EVP Dev & Med Affairs | Aug 03 | Sell | 186.14 | 7,627 | 1,419,690 | 4,345 | 08/07/23 |
Poulton Jeffrey V. | EVP, Chief Financial.. EVP, Chief Financial Officer | Aug 03 | Sell | 186.95 | 3,460 | 646,847 | 15,873 | 08/07/23 |
Greenstreet Yvonne | Chief Executive Offi.. Chief Executive Officer | Aug 03 | Sell | 186.95 | 4,057 | 758,456 | 35,216 | 08/07/23 |
Vaishnaw Akshay | President President | Aug 03 | Sell | 186.95 | 4,057 | 758,456 | 22,774 | 08/07/23 |
Greenstreet Yvonne | Chief Executive Offi.. Chief Executive Officer | Apr 26 | Sell | 194.96 | 7,615 | 1,484,620 | 30,332 | 04/28/23 |
Poulton Jeffrey V. | EVP, Chief Financial.. EVP, Chief Financial Officer | Apr 26 | Sell | 194.96 | 977 | 190,476 | 11,706 | 04/28/23 |
Tanguler Tolga | EVP, Chief Commercia.. EVP, Chief Commercial Officer | Apr 26 | Sell | 194.96 | 1,476 | 287,761 | 1,801 | 04/28/23 |
Vaishnaw Akshay | President President | Apr 26 | Sell | 194.96 | 2,392 | 466,344 | 17,890 | 04/28/23 |
Garg Pushkal | CMO & EVP Dev & Med.. CMO & EVP Dev & Med Affairs | Apr 26 | Sell | 196.92 | 4,294 | 845,574 | 4,345 | 04/28/23 |
Franchini Indrani Lall | EVP, CLO & Secretary EVP, CLO & Secretary | Feb 01 | Sell | 225.94 | 1,675 | 378,450 | 3,500 | 02/03/23 |
Franchini Indrani Lall | EVP, CLO & Secretary EVP, CLO & Secretary | Feb 01 | Option | 0 | 5,175 | 5,175 | 02/03/23 | |
Tanguler Tolga | EVP, Chief Commercia.. EVP, Chief Commercial Officer | Feb 01 | Sell | 228.76 | 5,025 | 1,149,519 | 02/03/23 | |
Tanguler Tolga | EVP, Chief Commercia.. EVP, Chief Commercial Officer | Feb 01 | Option | 0 | 5,025 | 5,025 | 02/03/23 | |
Tanguler Tolga | EVP, Chief Commercia.. EVP, Chief Commercial Officer | Jul 05 | Sell | 150.0 | 1,754 | 263,100 | 1,754 | 07/07/22 |
Vaishnaw Akshay | President, R&D President, R&D | Dec 21 | Sell | 190.24 | 2,879 | 547,701 | 11,215 | 12/23/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Nov 12 | Sell | 172.3 | 33,978 | 5,854,409 | 214,765 | 11/12/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Nov 12 | Option | 7.1 | 33,978 | 241,244 | 248,743 | 11/12/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | May 17 | Option | 7.1 | 33,979 | 241,251 | 248,744 | 05/17/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | May 17 | Sell | 131.34 | 33,979 | 4,462,802 | 214,765 | 05/17/21 |
Vaishnaw Akshay | President, R&D President, R&D | Apr 21 | Sell | 137.67 | 6,438 | 886,319 | 14,119 | 04/21/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Feb 26 | Option | 7.1 | 33,979 | 241,251 | 240,015 | 02/26/21 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Feb 26 | Sell | 149.18 | 33,979 | 5,068,987 | 206,036 | 02/26/21 |
KEATING LAURIE | EVP, Chief Legal Off.. EVP, Chief Legal Officer | Jan 15 | Option | 81.2 | 9,027 | 732,992 | 11,261 | 01/15/21 |
KEATING LAURIE | EVP, Chief Legal Off.. EVP, Chief Legal Officer | Jan 15 | Sell | 171 | 9,027 | 1,543,617 | 2,234 | 01/15/21 |
PAUL STEVEN M | Director Director | Dec 22 | Option | 9.3 | 15,000 | 139,500 | 16,000 | 12/22/20 |
PAUL STEVEN M | Director Director | Dec 22 | Sell | 140 | 15,000 | 2,100,000 | 1,000 | 12/22/20 |
SHARP PHILLIP A | Director Director | Nov 30 | Option | 9.3 | 30,000 | 279,000 | 265,633 | 11/30/20 |
SHARP PHILLIP A | Director Director | Nov 30 | Sell | 125.74 | 30,000 | 3,772,200 | 235,633 | 11/30/20 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Nov 20 | Option | 9.14 | 34,765 | 317,752 | 232,354 | 11/20/20 |
MARAGANORE JOHN | Chief Executive Offi.. Chief Executive Officer | Nov 20 | Sell | 125 | 34,765 | 4,345,625 | 197,589 | 11/20/20 |
Vaishnaw Akshay | President, R&D President, R&D | Oct 01 | Option | 42.22 | 971 | 40,996 | 15,090 | 10/01/20 |
Vaishnaw Akshay | President, R&D President, R&D | Oct 01 | Sell | 140 | 971 | 135,940 | 14,119 | 10/01/20 |